Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   C5L38_RS06500 Genome accession   NZ_CP027022
Coordinates   1425022..1425648 (+) Length   208 a.a.
NCBI ID   WP_062751542.1    Uniprot ID   A0AAV4KTT2
Organism   Streptomyces sp. WAC00288     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1420022..1430648
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C5L38_RS06480 (C5L38_06480) - 1420970..1421776 (+) 807 WP_062751538.1 IclR family transcriptional regulator -
  C5L38_RS06485 (C5L38_06485) - 1421845..1422525 (-) 681 WP_062751539.1 ABC transporter ATP-binding protein -
  C5L38_RS06490 (C5L38_06490) - 1422586..1423665 (-) 1080 WP_062751540.1 ABC transporter permease -
  C5L38_RS06495 (C5L38_06495) - 1423778..1425025 (+) 1248 WP_062751541.1 sensor histidine kinase -
  C5L38_RS06500 (C5L38_06500) vraR 1425022..1425648 (+) 627 WP_062751542.1 response regulator transcription factor Regulator
  C5L38_RS06505 (C5L38_06505) - 1425720..1426049 (-) 330 WP_062751543.1 DUF5955 family protein -
  C5L38_RS06510 (C5L38_06510) - 1426266..1426904 (+) 639 WP_062751544.1 nucleotidyltransferase family protein -
  C5L38_RS06515 (C5L38_06515) aceB 1427220..1428842 (+) 1623 WP_062751545.1 malate synthase A -
  C5L38_RS06520 (C5L38_06520) - 1429103..1430248 (+) 1146 WP_062751546.1 GDSL-type esterase/lipase family protein -

Sequence

Protein


Download         Length: 208 a.a.        Molecular weight: 21490.78 Da        Isoelectric Point: 6.0056

>NTDB_id=229853 C5L38_RS06500 WP_062751542.1 1425022..1425648(+) (vraR) [Streptomyces sp. WAC00288]
MTIRLLLADDHPVVRAGLRAVLDTEPDFAVVAEAATAERAVELAAAGGVDVVLMDLQFGAGMHGSEATAAITAAPGGPKV
LVLTTYDTDVDILAAVEAGASGYLLKDAPPEELAAAVRTAAAGQSALAPAVAHRLMDRMRTPAEALTKRELEVLQLVGEG
LSNAQISKALFLSQATVKSHLVHVFAKLGVDSRTAAVAAATARRLIRR

Nucleotide


Download         Length: 627 bp        

>NTDB_id=229853 C5L38_RS06500 WP_062751542.1 1425022..1425648(+) (vraR) [Streptomyces sp. WAC00288]
ATGACCATCCGTCTCCTGCTCGCCGACGACCATCCGGTGGTACGGGCGGGCCTGCGCGCGGTCCTGGACACCGAGCCGGA
CTTCGCGGTCGTCGCGGAGGCCGCCACCGCCGAGCGCGCGGTGGAGCTGGCCGCCGCCGGGGGCGTGGACGTGGTCCTGA
TGGACCTCCAGTTCGGCGCGGGGATGCACGGCTCGGAGGCGACGGCGGCGATCACGGCGGCGCCGGGCGGGCCGAAGGTG
CTGGTCCTGACGACGTACGACACGGACGTGGACATCCTGGCGGCGGTGGAGGCGGGCGCCTCCGGCTACCTCCTGAAGGA
CGCGCCGCCGGAGGAGCTGGCGGCGGCGGTCCGGACGGCGGCGGCCGGCCAGTCGGCGCTCGCGCCGGCGGTGGCGCACC
GGCTGATGGACCGGATGCGGACCCCGGCGGAGGCGCTGACCAAGCGGGAGCTGGAGGTGCTCCAGCTGGTCGGCGAGGGC
CTGTCGAACGCGCAGATCAGCAAGGCGCTGTTCCTGAGCCAGGCGACGGTGAAGTCCCATCTGGTCCACGTCTTCGCGAA
GCTGGGCGTGGACTCCCGCACGGCGGCGGTGGCGGCGGCGACGGCCCGGCGTCTGATCAGGCGGTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-117)

Bacterial regulatory proteins, luxR family (GerE)

(145-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0AAV4KTT2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.095

100

0.385
  degU Bacillus subtilis subsp. subtilis str. 168

34.404

100

0.361