Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   C5L38_RS00835 Genome accession   NZ_CP027022
Coordinates   181374..182066 (+) Length   230 a.a.
NCBI ID   WP_062760312.1    Uniprot ID   -
Organism   Streptomyces sp. WAC00288     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 176374..187066
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C5L38_RS00825 (C5L38_00825) - 179353..180123 (+) 771 WP_234363691.1 CPBP family intramembrane glutamic endopeptidase -
  C5L38_RS00830 (C5L38_00830) - 180149..181369 (+) 1221 WP_104860316.1 histidine kinase -
  C5L38_RS00835 (C5L38_00835) vraR 181374..182066 (+) 693 WP_062760312.1 response regulator transcription factor Regulator
  C5L38_RS00840 (C5L38_00840) - 182610..183194 (-) 585 WP_234363692.1 TspO/MBR family protein -
  C5L38_RS36445 - 183219..183329 (+) 111 Protein_169 IS5/IS1182 family transposase -
  C5L38_RS36450 - 183404..183549 (-) 146 Protein_170 IS5/IS1182 family transposase -
  C5L38_RS00845 (C5L38_00845) - 183549..183833 (+) 285 WP_062760307.1 hypothetical protein -
  C5L38_RS00850 (C5L38_00850) - 183960..184397 (+) 438 WP_062760304.1 hypothetical protein -
  C5L38_RS00855 (C5L38_00855) - 184454..185386 (-) 933 WP_062760302.1 anti-sigma factor RsbA family regulatory protein -
  C5L38_RS00860 (C5L38_00860) - 185383..185721 (-) 339 WP_062760512.1 STAS domain-containing protein -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 24717.59 Da        Isoelectric Point: 6.4886

>NTDB_id=229848 C5L38_RS00835 WP_062760312.1 181374..182066(+) (vraR) [Streptomyces sp. WAC00288]
MSDAPPPIRVLVCDDQALVRTGYVTIFSAQPDMEVVGEAENGHEAVQSARRLRPDVVVMDIRMPVLDGIQATRQLAGPDT
EGSPKVLVVTTFNVDAYVYDALRAGASGFLLKDAPPAELVNGIRTVARGEALLAPAVTRHLIGHFAQHLRPADTSRPARQ
NVVCALTPRELEVLQLIAEGLSNAEIAAAMFITPETVKTYVSRILAKLGLRDRVQAVVLAYRIGLVPGTP

Nucleotide


Download         Length: 693 bp        

>NTDB_id=229848 C5L38_RS00835 WP_062760312.1 181374..182066(+) (vraR) [Streptomyces sp. WAC00288]
GTGAGCGATGCGCCACCACCGATCCGTGTACTCGTCTGTGACGACCAGGCGCTGGTGCGGACCGGCTACGTCACCATCTT
CTCCGCCCAGCCCGACATGGAGGTCGTCGGAGAGGCCGAGAACGGCCACGAGGCGGTTCAGAGCGCGCGGCGGCTGCGCC
CCGACGTAGTCGTGATGGACATCCGCATGCCCGTGCTCGACGGCATCCAGGCGACGCGGCAGCTTGCCGGTCCCGATACC
GAGGGCTCGCCGAAAGTACTGGTCGTCACCACGTTCAACGTCGACGCCTACGTATACGACGCATTGCGTGCCGGAGCGAG
CGGCTTCCTGCTCAAGGACGCGCCGCCGGCGGAGCTGGTCAACGGTATCCGGACTGTCGCCCGGGGCGAGGCCCTGCTGG
CACCCGCCGTCACCCGCCACCTCATCGGCCACTTCGCCCAGCATCTGCGACCGGCCGACACCTCCCGGCCGGCCAGACAG
AACGTAGTGTGTGCGCTGACCCCCCGCGAGCTGGAAGTGCTCCAACTGATCGCCGAGGGGCTGTCGAACGCGGAGATCGC
CGCGGCGATGTTCATCACGCCCGAGACCGTCAAGACCTACGTGTCGCGCATTCTGGCGAAACTCGGCCTGCGCGACCGCG
TCCAGGCCGTCGTCCTCGCCTACCGGATCGGATTGGTGCCCGGTACGCCGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(10-123)

Bacterial regulatory proteins, luxR family (GerE)

(166-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.183

95.217

0.383
  degU Bacillus subtilis subsp. subtilis str. 168

37.778

97.826

0.37