Detailed information NTG0229561

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: RK68_RS12900
• Genome accession: NZ_CP026961
• Coordinates: 2394920..2395633 (-)
• Length: 237 a.a.
• NCBI ID: WP_001031454.1
• Uniprot ID: A0A0H2XG68
• Organism: Staphylococcus aureus strain FDAARGOS_10
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2389920..2400633

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RK68_RS12870 (RK68_12870)	-	2391114..2392319 (-)	1206	WP_000264748.1	tyrosine-type recombinase/integrase	-
RK68_RS12875 (RK68_12875)	-	2392445..2393059 (+)	615	WP_000191459.1	hypothetical protein	-
RK68_RS12880 (RK68_12880)	-	2393056..2393202 (-)	147	WP_001013104.1	hypothetical protein	-
RK68_RS12885 (RK68_12885)	-	2393239..2393421 (-)	183	WP_000705240.1	hypothetical protein	-
RK68_RS12890 (RK68_12890)	-	2393625..2393966 (-)	342	WP_000591749.1	hypothetical protein	-
RK68_RS12895 (RK68_12895)	-	2393972..2394904 (-)	933	WP_000759682.1	exonuclease domain-containing protein	-
RK68_RS12900 (RK68_12900)	irvR	2394920..2395633 (-)	714	WP_001031454.1	XRE family transcriptional regulator	Regulator
RK68_RS12905 (RK68_12905)	-	2395596..2395769 (+)	174	WP_001801500.1	hypothetical protein	-
RK68_RS12910 (RK68_12910)	-	2395766..2396029 (+)	264	WP_000854072.1	helix-turn-helix transcriptional regulator	-
RK68_RS12915 (RK68_12915)	-	2396045..2396290 (+)	246	WP_001025402.1	DUF2829 domain-containing protein	-
RK68_RS12920 (RK68_12920)	-	2396259..2396624 (-)	366	WP_001131647.1	hypothetical protein	-
RK68_RS12925 (RK68_12925)	-	2396679..2396894 (+)	216	WP_001097552.1	hypothetical protein	-
RK68_RS12930 (RK68_12930)	-	2396919..2397182 (+)	264	WP_001124160.1	helix-turn-helix domain-containing protein	-
RK68_RS12935 (RK68_12935)	-	2397195..2397356 (+)	162	WP_001285961.1	DUF1270 domain-containing protein	-
RK68_RS12940 (RK68_12940)	-	2397435..2397758 (+)	324	WP_000174996.1	hypothetical protein	-
RK68_RS12945 (RK68_12945)	-	2397773..2398135 (+)	363	WP_000279452.1	hypothetical protein	-
RK68_RS12950 (RK68_12950)	-	2398132..2399298 (+)	1167	WP_000762540.1	DUF2800 domain-containing protein	-
RK68_RS12955 (RK68_12955)	-	2399324..2399881 (+)	558	WP_000645042.1	DUF2815 family protein	-

Sequence

Protein

• Length: 237 a.a.
• Molecular weight: 27017.58 Da
• Isoelectric Point: 5.0545

>NTDB_id=229561 RK68_RS12900 WP_001031454.1 2394920..2395633(-) (irvR) [Staphylococcus aureus strain FDAARGOS_10]
MNKERNIIIAKNIRKFLNDSNMSQKKLAELINIKPSTLSDYLNLRSNPSHGVIQRIADVFEVGKSDIDTTYKDDNDITSI
YNKLTPPRQENVLNYANEQLEEQNSKGDNVVDINSYKQEKTPVNVNGCVSAGVGERLHDETLFTEMVKGPIPTHDLALKV
NGDSMEPMFKDGEIIFVEKTHNIKNGQIGIFIIEEEAYVKKVFVEDDRLTLVSLNKDYDDLHFYRNESVRLIGKVIL

Nucleotide

• Length: 714 bp

>NTDB_id=229561 RK68_RS12900 WP_001031454.1 2394920..2395633(-) (irvR) [Staphylococcus aureus strain FDAARGOS_10]
ATGAACAAAGAAAGAAATATTATTATAGCCAAAAACATTAGAAAATTTCTCAACGATTCAAATATGTCTCAAAAGAAACT
TGCTGAACTCATTAACATAAAACCATCTACTTTAAGCGATTATTTAAATTTACGTTCCAACCCCTCTCACGGCGTTATAC
AAAGGATAGCTGATGTTTTCGAGGTTGGTAAAAGCGACATAGATACTACATACAAAGACGATAACGACATCACTTCCATA
TACAACAAACTCACACCTCCCCGCCAAGAAAACGTACTTAACTATGCAAATGAACAATTGGAAGAACAGAATTCTAAAGG
AGATAACGTTGTAGATATTAATTCATATAAACAGGAGAAAACTCCAGTTAACGTCAATGGTTGCGTCTCTGCTGGTGTAG
GAGAACGTTTACACGATGAAACGCTATTTACTGAAATGGTTAAAGGACCTATCCCCACACACGATTTAGCGTTAAAAGTA
AATGGTGATTCTATGGAACCTATGTTTAAAGATGGCGAAATCATATTTGTGGAGAAAACTCACAATATAAAGAATGGACA
AATTGGTATATTCATCATTGAAGAAGAAGCGTACGTTAAGAAAGTCTTTGTTGAAGATGATAGATTGACTCTAGTTTCAC
TAAATAAAGATTACGACGATCTACACTTTTATAGAAATGAAAGTGTGAGGTTAATTGGAAAAGTTATTTTATAA

Domains

Predicted by InterProScan.

• Peptidase S24-like (Peptidase_S24) (127-236)

• Helix-turn-helix (HTH_3) (13-63)

3D structure

• AlphaFold DB: A0A0H2XG68

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	33.929	100	0.401