Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   CA929_RS08735 Genome accession   NZ_CP021277
Coordinates   1886547..1887875 (-) Length   442 a.a.
NCBI ID   WP_027227755.1    Uniprot ID   A0A2S6F2C9
Organism   Legionella pneumophila subsp. fraseri strain D-4058     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1881547..1892875
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CA929_RS08715 - 1882645..1883259 (-) 615 WP_027227758.1 riboflavin synthase -
  CA929_RS08720 ribD 1883244..1884317 (-) 1074 WP_027227757.1 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD -
  CA929_RS08725 - 1884380..1885816 (+) 1437 WP_027227756.1 M48 family metalloprotease -
  CA929_RS08730 - 1886127..1886372 (-) 246 WP_011213531.1 hypothetical protein -
  CA929_RS08735 pilR 1886547..1887875 (-) 1329 WP_027227755.1 sigma-54 dependent transcriptional regulator Regulator
  CA929_RS08740 - 1887872..1889458 (-) 1587 WP_027227754.1 ATP-binding protein -
  CA929_RS08745 lidL 1889557..1891041 (-) 1485 WP_080272128.1 Dot/Icm type IV secretion system effector LidL -
  CA929_RS08750 - 1891191..1891610 (-) 420 WP_027227752.1 lpg1171 family Dot/Icm T4SS effector -
  CA929_RS08755 amrS 1891669..1892745 (-) 1077 WP_027227751.1 AmmeMemoRadiSam system radical SAM enzyme -

Sequence

Protein


Download         Length: 442 a.a.        Molecular weight: 49266.25 Da        Isoelectric Point: 6.9042

>NTDB_id=229553 CA929_RS08735 WP_027227755.1 1886547..1887875(-) (pilR) [Legionella pneumophila subsp. fraseri strain D-4058]
MTKSKVLVIDDEPDIRELLTLTLSRMGLTCDAVSDFKQGIEHIKQNYYSLVLTDMRLPDGDGIEIVKFIQKYKPQVPVAV
ITAYGNVEGAVNTLKAGAFDYVSKPIDLKMLRDLVKTALSMQNPPTEKPDEDLLVGESLVMQQLRENIHKLARSQAPVFI
QGASGVGKELVAQLIHVNGPRKDKPFIPVNCGAIPGELMESEFFGHKKGSFTGAISDKTGLFVAAHGGTLFLDEIAELPL
AMQVKLLRAIQEKAIKPIGELYEVPVDVRILSASHKNLIEEVNAGAFRQDLYYRINVIELRVPTLMERLSDIPCLTEAIL
RKLSKNQNRNLVKINPSCFEILSRYHFPGNVRELENILERAMAMCEGEVIEPSDLHLPRTTITPAVAVPSTSTNLNGYLQ
DQEKELILDALEKTKWNRTAAAQLLGVSFRTLRYRLKKLGLD

Nucleotide


Download         Length: 1329 bp        

>NTDB_id=229553 CA929_RS08735 WP_027227755.1 1886547..1887875(-) (pilR) [Legionella pneumophila subsp. fraseri strain D-4058]
ATGACCAAAAGTAAAGTGCTTGTTATAGATGATGAACCAGATATAAGAGAGTTATTAACTCTTACTTTATCACGCATGGG
TTTAACTTGCGATGCAGTGTCTGACTTTAAGCAAGGCATAGAACATATAAAACAAAATTATTATTCTTTGGTTTTAACCG
ATATGCGTTTACCTGATGGAGATGGTATAGAAATTGTTAAATTCATTCAGAAATACAAACCGCAGGTACCAGTTGCCGTC
ATTACTGCCTATGGAAATGTCGAGGGTGCGGTCAACACTTTAAAGGCGGGTGCATTTGATTACGTATCAAAACCTATAGA
CTTAAAAATGCTTAGAGATCTCGTTAAGACGGCATTATCCATGCAAAACCCGCCTACCGAGAAGCCTGATGAAGATCTAC
TGGTTGGTGAAAGTTTGGTAATGCAACAACTTCGTGAAAACATTCATAAATTAGCTCGCAGTCAGGCACCAGTTTTTATT
CAAGGAGCTTCGGGTGTTGGAAAAGAATTGGTCGCTCAGTTGATCCATGTTAATGGTCCCAGAAAGGATAAGCCATTTAT
TCCTGTAAACTGCGGCGCTATACCTGGTGAGTTGATGGAATCAGAGTTTTTTGGCCATAAAAAAGGGAGCTTTACAGGAG
CGATTTCTGATAAAACAGGGTTGTTTGTTGCGGCTCATGGTGGCACTTTGTTTCTTGATGAAATCGCCGAACTTCCTCTC
GCTATGCAGGTTAAATTGCTACGTGCGATTCAGGAGAAGGCAATTAAGCCGATAGGTGAGTTATATGAAGTTCCTGTGGA
TGTTCGCATCCTAAGTGCAAGTCATAAAAATTTGATTGAGGAAGTTAATGCAGGGGCGTTTCGTCAAGATTTGTATTATC
GAATTAATGTGATTGAATTGCGTGTCCCAACTTTAATGGAAAGGCTTTCAGATATTCCTTGCCTGACAGAGGCGATATTA
AGAAAGTTATCTAAAAATCAAAATAGAAACCTGGTGAAAATAAATCCATCCTGTTTTGAAATATTGAGTCGTTATCATTT
TCCAGGAAATGTCAGAGAACTGGAGAATATCCTCGAGCGTGCTATGGCTATGTGTGAAGGAGAGGTTATAGAACCATCCG
ATTTACATTTGCCAAGAACAACAATAACCCCAGCTGTTGCCGTACCCTCCACGTCAACTAACTTAAATGGTTACCTTCAG
GATCAGGAAAAAGAGTTAATTCTTGATGCGCTTGAGAAAACAAAATGGAACAGAACCGCTGCTGCCCAATTATTAGGTGT
CAGCTTTCGCACTCTCCGTTATCGATTAAAAAAACTGGGACTTGATTAG

Domains

Predicted by InterproScan.

Bacterial regulatory protein, Fis family (HTH_8)

(399-439)

Response regulator receiver domain (Response_reg)

(6-115)

Sigma-54 interaction domain (Sigma54_activat)

(134-300)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2S6F2C9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

59.417

100

0.6
  pilR Acinetobacter baumannii strain A118

48.584

100

0.505

Multiple sequence alignment