Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   CA926_RS07460 Genome accession   NZ_CP021265
Coordinates   1661953..1663173 (+) Length   406 a.a.
NCBI ID   WP_027221710.1    Uniprot ID   A0A2S6EZN5
Organism   Legionella pneumophila subsp. fraseri strain Los Angeles     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1656953..1668173
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CA926_RS07440 - 1658046..1658615 (-) 570 WP_027221706.1 hypoxanthine-guanine phosphoribosyltransferase -
  CA926_RS07445 - 1658658..1658984 (-) 327 WP_028378907.1 DUF1820 family protein -
  CA926_RS07450 - 1659167..1659910 (-) 744 WP_027227021.1 methyltransferase domain-containing protein -
  CA926_RS07455 pilB 1660223..1661947 (+) 1725 WP_027227022.1 type IV-A pilus assembly ATPase PilB Machinery gene
  CA926_RS07460 pilC 1661953..1663173 (+) 1221 WP_027221710.1 type II secretion system F family protein Machinery gene
  CA926_RS07465 pilD 1663219..1664082 (+) 864 WP_027227023.1 A24 family peptidase Machinery gene
  CA926_RS07470 - 1664096..1665301 (-) 1206 WP_028379061.1 cyclic nucleotide-binding domain-containing protein -
  CA926_RS07475 - 1665411..1666004 (-) 594 WP_027227025.1 hypothetical protein -
  CA926_RS07480 - 1666020..1666475 (-) 456 WP_027227026.1 hypothetical protein -
  CA926_RS07485 - 1666623..1667438 (+) 816 WP_028378911.1 pyruvate, water dikinase regulatory protein -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 44641.85 Da        Isoelectric Point: 9.6052

>NTDB_id=229339 CA926_RS07460 WP_027221710.1 1661953..1663173(+) (pilC) [Legionella pneumophila subsp. fraseri strain Los Angeles]
MDKNAPPLLTFHYQGINKAGQKMEGDIQARSLAIAKADLRKQGIVTNKVVKKRKPLLDRKNKKITQADITVFSRQLATMI
ESGIPLVQAFDIVAKGQSNKRLKDLIETIKHDIETGLTLAESLIKHPLYFNELFCNLVDAGEKSGSLDIMLDKVATYKEK
IEIIKKKIKKALTYPIAVMVVALLVTAGLLIYVVPQFESLFKGFGADLPAMTRAVITMSEFMQAYWYIIFGALGGVVYSF
FYAKNHSLDFAQTIDRVMLKFPVIGPILEKAAIARFARTLSITFAAGLPLVEALKSVAGATGNIIYAKATDKIREEVATG
QQMFIAMENTHLFPNMVIQMVAIGEESGALEKMLSKVADFYEEEVNNAVDALSSLLEPIIMSILGILVGGLVVAMYLPIF
KLGSAV

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=229339 CA926_RS07460 WP_027221710.1 1661953..1663173(+) (pilC) [Legionella pneumophila subsp. fraseri strain Los Angeles]
ATGGATAAAAATGCCCCACCTTTATTAACCTTTCATTATCAAGGCATCAATAAAGCTGGTCAAAAAATGGAAGGTGATAT
TCAAGCCAGAAGCTTGGCAATAGCTAAAGCTGATTTGCGTAAACAAGGAATAGTCACTAATAAAGTAGTTAAAAAAAGAA
AACCCTTGTTGGATAGAAAAAATAAAAAAATCACGCAAGCGGATATTACAGTGTTTAGCCGCCAATTAGCTACGATGATA
GAGTCAGGGATACCATTAGTACAAGCGTTTGATATTGTTGCCAAAGGACAAAGTAATAAAAGGCTTAAAGACTTGATAGA
AACAATTAAGCACGATATTGAAACGGGGCTAACGCTAGCAGAATCGTTAATTAAACATCCACTCTATTTTAATGAATTAT
TCTGTAATCTTGTCGATGCAGGTGAAAAATCAGGTTCATTAGATATTATGCTTGACAAGGTTGCAACGTATAAAGAAAAA
ATTGAAATCATAAAAAAGAAAATAAAGAAAGCTTTAACTTACCCAATTGCAGTTATGGTTGTCGCGCTTTTGGTTACTGC
AGGATTGTTAATCTACGTGGTTCCTCAATTTGAATCGCTGTTCAAAGGATTTGGCGCTGATTTGCCAGCGATGACCAGAG
CTGTAATTACTATGTCTGAATTTATGCAGGCCTATTGGTATATTATTTTTGGTGCTTTGGGTGGAGTTGTCTATAGCTTT
TTTTATGCCAAAAATCATTCTTTAGATTTCGCGCAAACCATTGACCGAGTAATGCTAAAGTTTCCTGTGATAGGACCTAT
TTTAGAGAAAGCTGCTATTGCTCGATTTGCGAGGACACTATCTATTACTTTTGCTGCTGGATTACCTTTAGTTGAAGCTT
TGAAATCTGTAGCTGGAGCGACTGGAAATATTATTTATGCCAAGGCAACTGATAAAATAAGAGAGGAAGTTGCCACAGGG
CAGCAAATGTTTATTGCTATGGAAAATACCCATTTATTCCCAAATATGGTAATTCAAATGGTAGCAATTGGTGAGGAATC
AGGTGCCCTTGAGAAAATGTTAAGCAAGGTTGCTGATTTTTATGAGGAAGAAGTAAATAATGCTGTAGATGCTCTGAGTA
GTTTATTGGAGCCTATAATTATGTCAATATTAGGCATCCTTGTTGGGGGATTGGTCGTGGCTATGTATTTGCCTATCTTC
AAACTGGGCTCTGCTGTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(276-398)

Type II secretion system (T2SS), protein F (T2SSF)

(72-195)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2S6EZN5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Legionella pneumophila strain ERS1305867

99.015

100

0.99
  pilC Acinetobacter baumannii D1279779

54.074

99.754

0.539
  pilC Pseudomonas stutzeri DSM 10701

54.293

97.537

0.53
  pilC Acinetobacter baylyi ADP1

53.401

97.783

0.522
  pilG Neisseria meningitidis 44/76-A

45.088

97.783

0.441
  pilG Neisseria gonorrhoeae MS11

44.836

97.783

0.438
  pilC Vibrio cholerae strain A1552

42.5

98.522

0.419
  pilC Vibrio campbellii strain DS40M4

39.409

100

0.394

Multiple sequence alignment