Detailed information NTG0229180

Bioinformatically predicted

Overview

• Name: letS
• Type: Regulator
• Locus tag: CA934_RS09955
• Genome accession: NZ_CP021259
• Coordinates: 2171739..2174471 (+)
• Length: 910 a.a.
• NCBI ID: WP_028379420.1
• Uniprot ID: -
• Organism: Legionella pneumophila strain D-7708
• Function: regulate competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2166739..2179471

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CA934_RS09935	gstA	2166887..2167492 (-)	606	WP_028378748.1	glutathione transferase GstA	-
CA934_RS09940	-	2167689..2168684 (-)	996	WP_028379422.1	hypothetical protein	-
CA934_RS09945	-	2168725..2169987 (-)	1263	WP_106225444.1	serine hydrolase domain-containing protein	-
CA934_RS09950	gltX	2170228..2171640 (-)	1413	WP_028378745.1	glutamate--tRNA ligase	-
CA934_RS09955	letS	2171739..2174471 (+)	2733	WP_028379420.1	two-component system sensor histidine kinase LetS	Regulator
CA934_RS09960	-	2174568..2175812 (+)	1245	WP_028378744.1	6-phosphofructokinase	-
CA934_RS09965	pilA2	2175809..2176222 (-)	414	WP_028378743.1	pilin	Machinery gene
CA934_RS09970	pilA2	2176434..2176844 (-)	411	WP_014844212.1	pilin	Machinery gene
CA934_RS09975	-	2177147..2177464 (+)	318	WP_106225445.1	BolA/IbaG family iron-sulfur metabolism protein	-
CA934_RS09980	-	2177539..2178960 (+)	1422	WP_106225446.1	APC family permease	-

Sequence

Protein

• Length: 910 a.a.
• Molecular weight: 103049.52 Da
• Isoelectric Point: 7.6543

>NTDB_id=229180 CA934_RS09955 WP_028379420.1 2171739..2174471(+) (letS) [Legionella pneumophila strain D-7708]
MLKSIGIKYQLRITTLIPAFLVALLFAFFYNGLFGKDLKQHMSRLGEAYIRQLLPAAQYAMLRNDYRTLQGLINASTINP
EVKALAFYNADGRLIAYRGGKHSIHKPFNPPDFTGDYIESKQINPFTINFIAPITIPKFNLYSSTEFKELSTPKIFQADD
ILGWLSIDIDTQSLLIKRYQMLIVTIFITLFGLLMGLTIHYFLSKRIYMPIARLRRSMKQILSNEFETEIRVSSPGELGI
IEKGCAHLQRQYLNTVRDLNHHIEIATADLQQSLELLEEKNIELSLEKKKTEEKSRQKSEFIANMSHEIRTPMNGVIGFT
NVLLESKLDPLQLDYVKTIKSSAQDLLSIINDILDFSKIDAGKLNLDCIPLDIRGCIDEVLSLASPNAHKKGIDLIPITD
INVPKMVLGDPLRIKQIISNLVTNAVKFTDHGYVLIRTKIEQETDKDYTLLFAITDTGIGISPEDQTKLFTAFNQADTSI
TRRYGGSGLGLVICKKLCEEMHGRISLTSEINKGSTFSARIKVEKLIAYEIEKNQTHRFAHLKIICFDDNPLHLEAIGNG
LGFWGIEAIRVDSFNKLSRTLTKHKDCRIAFINVNQGCERQAAELIAKHKQIPFVLISKWPINDFAALGARGFLYKPISI
QKLQDLIESIANENQIEKNTNQELDTLREQLRFLHPDLLIAEDNPVNKMLLTSLLNNNTNITTVDDGEMAVAACEDKKFD
MILLDLQMPKLNGLEAAKMIRQKSLMNKHSPIVLITASSNDLSSIDMKKSGVDFCFQKPIDEKQLLIQILRIVDKTKHAA
IDWQLCVQKVSGNQALAEEFLAKFIEELYKNREEFIQLMHQKNVKGLADLAHKLHGACCFCGVPTLQKRVSQLEKLARRT
ANADNLSEAFTDLIQSIDAVISEYENQYSQ

Nucleotide

• Length: 2733 bp

>NTDB_id=229180 CA934_RS09955 WP_028379420.1 2171739..2174471(+) (letS) [Legionella pneumophila strain D-7708]
ATGTTGAAAAGTATTGGTATTAAGTATCAGCTAAGAATCACTACTCTTATTCCTGCCTTTTTAGTCGCCTTGCTTTTTGC
CTTTTTTTATAACGGTCTATTTGGTAAAGACCTAAAGCAACATATGTCCAGGCTGGGTGAAGCCTACATTAGACAATTAC
TCCCAGCCGCCCAGTATGCCATGCTTCGCAATGATTATCGTACATTGCAGGGTTTAATCAATGCCTCAACCATTAACCCG
GAGGTAAAGGCTTTGGCATTTTATAATGCCGATGGCCGATTAATTGCTTATCGTGGTGGAAAACACTCTATCCATAAACC
CTTCAATCCCCCTGACTTTACAGGTGACTACATTGAAAGTAAGCAAATTAATCCATTCACCATTAATTTTATAGCGCCGA
TTACTATCCCAAAGTTCAATTTGTACTCCAGCACAGAATTCAAAGAGCTTTCTACGCCTAAAATATTCCAGGCTGACGAT
ATATTAGGCTGGTTATCCATTGACATTGATACGCAATCATTACTTATAAAACGCTATCAAATGCTTATTGTTACCATTTT
CATTACTCTTTTCGGCTTACTGATGGGTTTAACAATTCATTACTTCTTATCTAAACGAATTTACATGCCTATAGCTCGAT
TGCGTCGAAGCATGAAGCAAATTTTAAGTAACGAATTTGAAACCGAAATTCGTGTTTCAAGCCCCGGAGAATTAGGAATA
ATTGAAAAAGGTTGCGCTCATTTGCAACGACAATATTTAAATACGGTTCGTGATCTGAATCACCATATTGAAATCGCTAC
CGCGGATCTGCAACAAAGTCTCGAACTTCTAGAAGAAAAAAATATTGAACTGTCACTGGAGAAGAAAAAAACTGAAGAAA
AAAGCCGACAAAAATCAGAATTTATTGCCAACATGAGTCATGAAATACGCACCCCAATGAATGGAGTGATTGGTTTTACA
AATGTTTTATTGGAAAGCAAGCTGGATCCTTTACAACTGGACTACGTTAAAACAATCAAATCATCAGCGCAGGATTTATT
AAGTATTATCAATGATATTCTGGATTTTTCCAAAATTGATGCGGGCAAATTAAACCTTGATTGCATCCCGCTAGATATAA
GAGGTTGCATTGATGAGGTTTTATCCCTGGCAAGCCCCAATGCCCACAAAAAAGGAATCGATTTAATCCCGATTACAGAC
ATCAATGTGCCCAAAATGGTATTGGGTGACCCTTTAAGAATCAAACAAATCATCAGTAATCTGGTGACCAATGCAGTAAA
ATTTACGGACCATGGATACGTTCTTATACGCACTAAAATCGAGCAAGAGACAGATAAAGATTATACCTTGCTATTTGCCA
TCACGGATACGGGAATAGGCATTTCACCAGAGGATCAAACGAAACTGTTTACCGCCTTCAATCAGGCGGACACCAGCATC
ACACGCCGCTACGGTGGCTCAGGACTAGGCCTGGTTATATGTAAAAAACTATGTGAAGAAATGCATGGACGTATTAGTCT
AACCAGTGAAATCAACAAAGGCTCCACTTTTAGCGCACGCATTAAAGTTGAAAAACTAATCGCTTATGAAATTGAAAAAA
ATCAAACTCATCGTTTCGCCCATTTAAAAATCATTTGCTTTGATGATAATCCCCTCCATTTGGAAGCAATAGGTAATGGT
TTGGGCTTTTGGGGCATAGAGGCTATACGCGTTGATTCATTCAATAAGCTTTCCCGAACATTAACAAAACATAAAGATTG
CAGAATCGCCTTTATTAACGTCAATCAAGGATGTGAGCGTCAAGCTGCTGAACTCATTGCCAAACATAAGCAAATTCCTT
TCGTATTAATTTCCAAATGGCCTATCAATGATTTTGCGGCACTAGGTGCCAGAGGATTTCTTTACAAACCTATCAGCATT
CAAAAACTTCAAGATCTCATCGAATCGATAGCCAATGAAAATCAAATCGAGAAAAATACGAACCAGGAACTGGATACTTT
GCGCGAACAACTTCGCTTTCTTCATCCAGACTTACTGATTGCGGAAGACAATCCCGTCAATAAAATGCTATTAACATCCT
TATTAAACAACAATACCAATATAACAACAGTTGATGATGGTGAAATGGCTGTTGCTGCTTGCGAAGATAAAAAATTTGAC
ATGATTTTACTGGATCTGCAAATGCCAAAACTTAATGGGTTAGAAGCAGCTAAAATGATACGTCAAAAATCCCTGATGAA
TAAACACTCTCCTATCGTTCTCATTACTGCCAGTAGCAATGATCTGAGCTCCATCGATATGAAAAAATCCGGAGTTGATT
TTTGTTTTCAAAAGCCTATAGATGAAAAGCAATTGTTAATCCAAATTCTTCGCATTGTTGATAAAACCAAACATGCTGCC
ATCGATTGGCAATTATGTGTTCAGAAAGTTTCAGGTAATCAAGCGCTTGCTGAAGAGTTCCTCGCCAAATTTATAGAAGA
ATTATATAAGAATCGTGAAGAATTTATTCAGTTAATGCATCAAAAAAACGTAAAGGGCTTGGCTGATTTAGCTCATAAAT
TACATGGTGCCTGTTGTTTTTGTGGTGTGCCTACTTTACAAAAGAGAGTATCTCAATTAGAGAAGCTTGCAAGACGAACA
GCTAATGCTGATAATTTAAGCGAAGCCTTTACCGATTTAATACAAAGTATTGATGCGGTGATTAGTGAATATGAAAATCA
GTACTCACAATAA

Domains

Predicted by InterproScan.

• Hpt domain (Hpt) (819-900)

• His Kinase A (phospho-acceptor) domain (HisKA) (298-362)

• Single cache domain 4 (sCache_4) (36-180)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (409-524)

• Response regulator receiver domain (Response_reg) (679-787)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
letS	Legionella pneumophila strain ERS1305867	98.242	100	0.982