Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   CAC37_RS12910 Genome accession   NZ_CP021178
Coordinates   2610780..2611445 (-) Length   221 a.a.
NCBI ID   WP_000697873.1    Uniprot ID   -
Organism   Staphylococcus aureus subsp. aureus ST398 strain 2012-3     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2605780..2616445
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CAC37_RS12890 (CAC37_13390) - 2606240..2606353 (-) 114 WP_014937089.1 hypothetical protein -
  CAC37_RS12895 (CAC37_13395) - 2607022..2609022 (-) 2001 WP_000776741.1 ABC transporter permease -
  CAC37_RS12900 (CAC37_13400) - 2609019..2609774 (-) 756 WP_000923768.1 ABC transporter ATP-binding protein -
  CAC37_RS12905 (CAC37_13405) braS 2609882..2610769 (-) 888 WP_000143420.1 nisin susceptibility-associated two-component system sensor histidine kinase NsaS Regulator
  CAC37_RS12910 (CAC37_13410) braR 2610780..2611445 (-) 666 WP_000697873.1 nisin susceptibility-associated two-component system response regulator NsaR Regulator
  CAC37_RS12915 (CAC37_13415) - 2611471..2611671 (-) 201 WP_000604731.1 hypothetical protein -
  CAC37_RS12920 (CAC37_13420) - 2611869..2613293 (+) 1425 WP_000953736.1 alkaline phosphatase -
  CAC37_RS13460 (CAC37_13425) - 2613353..2613454 (-) 102 WP_000731972.1 SE2200 family small protein -
  CAC37_RS12930 (CAC37_13430) - 2613576..2614031 (-) 456 WP_000106185.1 MarR family winged helix-turn-helix transcriptional regulator -
  CAC37_RS12935 (CAC37_13435) - 2614275..2615036 (-) 762 WP_000323448.1 alpha/beta hydrolase -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25434.46 Da        Isoelectric Point: 4.6079

>NTDB_id=228966 CAC37_RS12910 WP_000697873.1 2610780..2611445(-) (braR) [Staphylococcus aureus subsp. aureus ST398 strain 2012-3]
MKILIVEDDFVIAESLASELEKWNYGVIVVEQFDDILSIFNQHQPQLVLLDINLPTLNGFHWCQEIRKTSNVPIIFISSR
IDNMDQIMAIQMGGDDFIEKPFNLSLTIAKIQALLRRTYDLSVANDSMTVKGCTLILDEAKVVYQEQNIQLSLTELQILK
LLFQNEDKYVSRTALIEKCWESENFIDDNTLAVNMTRLRKKLNTIGVNDFIITKKNVGYKV

Nucleotide


Download         Length: 666 bp        

>NTDB_id=228966 CAC37_RS12910 WP_000697873.1 2610780..2611445(-) (braR) [Staphylococcus aureus subsp. aureus ST398 strain 2012-3]
ATGAAAATATTAATTGTTGAAGATGATTTTGTTATAGCAGAAAGTTTAGCATCTGAACTTGAAAAATGGAATTACGGTGT
TATTGTCGTTGAACAATTTGATGATATACTGTCTATCTTTAACCAACATCAACCTCAGCTTGTATTGCTAGATATTAATT
TGCCAACGTTAAATGGTTTTCATTGGTGTCAAGAAATCCGAAAAACATCTAATGTGCCAATTATATTTATTAGTTCCCGT
ATTGATAATATGGACCAAATTATGGCAATACAAATGGGGGGAGATGATTTTATCGAAAAGCCATTTAACTTGTCATTAAC
GATTGCCAAAATTCAAGCATTATTGAGACGAACTTATGACTTGTCAGTAGCTAATGATTCGATGACGGTTAAAGGTTGTA
CATTAATATTAGATGAAGCAAAAGTCGTGTATCAAGAACAAAACATACAGCTATCTTTGACTGAATTACAAATATTAAAG
TTATTATTTCAAAATGAAGATAAATATGTAAGTAGAACTGCTTTAATTGAAAAATGTTGGGAATCAGAAAACTTCATAGA
TGATAACACATTAGCTGTTAACATGACTCGCCTGCGTAAAAAATTAAATACTATTGGCGTTAATGATTTTATCATTACAA
AGAAAAATGTCGGATATAAAGTATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-111)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

99.095

100

0.991

Multiple sequence alignment