Detailed information NTG0228965

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: CAC37_RS12905
• Genome accession: NZ_CP021178
• Coordinates: 2609882..2610769 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus subsp. aureus ST398 strain 2012-3
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2604882..2615769

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CAC37_RS12875 (CAC37_13370)	-	2604891..2604983 (+)	93	WP_031774855.1	hypothetical protein	-
CAC37_RS12880 (CAC37_13375)	-	2605091..2605588 (-)	498	WP_001065267.1	glutathione peroxidase	-
CAC37_RS12885 (CAC37_13380)	-	2605598..2605858 (-)	261	WP_014937088.1	hypothetical protein	-
CAC37_RS12890 (CAC37_13390)	-	2606240..2606353 (-)	114	WP_014937089.1	hypothetical protein	-
CAC37_RS12895 (CAC37_13395)	-	2607022..2609022 (-)	2001	WP_000776741.1	ABC transporter permease	-
CAC37_RS12900 (CAC37_13400)	-	2609019..2609774 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
CAC37_RS12905 (CAC37_13405)	braS	2609882..2610769 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
CAC37_RS12910 (CAC37_13410)	braR	2610780..2611445 (-)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
CAC37_RS12915 (CAC37_13415)	-	2611471..2611671 (-)	201	WP_000604731.1	hypothetical protein	-
CAC37_RS12920 (CAC37_13420)	-	2611869..2613293 (+)	1425	WP_000953736.1	alkaline phosphatase	-
CAC37_RS13460 (CAC37_13425)	-	2613353..2613454 (-)	102	WP_000731972.1	SE2200 family small protein	-
CAC37_RS12930 (CAC37_13430)	-	2613576..2614031 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
CAC37_RS12935 (CAC37_13435)	-	2614275..2615036 (-)	762	WP_000323448.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=228965 CAC37_RS12905 WP_000143420.1 2609882..2610769(-) (braS) [Staphylococcus aureus subsp. aureus ST398 strain 2012-3]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=228965 CAC37_RS12905 WP_000143420.1 2609882..2610769(-) (braS) [Staphylococcus aureus subsp. aureus ST398 strain 2012-3]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993