Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   CAC37_RS07445 Genome accession   NZ_CP021178
Coordinates   1572996..1573682 (-) Length   228 a.a.
NCBI ID   WP_001825349.1    Uniprot ID   -
Organism   Staphylococcus aureus subsp. aureus ST398 strain 2012-3     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1567996..1578682
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CAC37_RS07425 (CAC37_07730) rpsT 1568910..1569161 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  CAC37_RS07430 (CAC37_07735) holA 1569206..1570180 (-) 975 WP_001282570.1 DNA polymerase III subunit delta -
  CAC37_RS07435 (CAC37_07740) comEC 1570237..1572438 (-) 2202 WP_001807826.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  CAC37_RS07440 (CAC37_07745) - 1572443..1572904 (-) 462 WP_000439690.1 ComE operon protein 2 -
  CAC37_RS07445 (CAC37_07750) comEA 1572996..1573682 (-) 687 WP_001825349.1 ComEA family DNA-binding protein Machinery gene
  CAC37_RS07450 (CAC37_07755) - 1573722..1574438 (-) 717 WP_000084838.1 class I SAM-dependent DNA methyltransferase -
  CAC37_RS07455 (CAC37_07760) rsfS 1574441..1574794 (-) 354 WP_001088020.1 ribosome silencing factor -
  CAC37_RS07460 (CAC37_07765) yqeK 1574795..1575379 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  CAC37_RS07465 (CAC37_07770) nadD 1575369..1575938 (-) 570 WP_000725164.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  CAC37_RS07470 (CAC37_07775) yhbY 1575941..1576231 (-) 291 WP_000955234.1 ribosome assembly RNA-binding protein YhbY -
  CAC37_RS07475 (CAC37_07780) aroE 1576235..1577041 (-) 807 WP_000666746.1 shikimate dehydrogenase -
  CAC37_RS07480 (CAC37_07785) yqeH 1577055..1578155 (-) 1101 WP_001280151.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25783.41 Da        Isoelectric Point: 9.3305

>NTDB_id=228950 CAC37_RS07445 WP_001825349.1 1572996..1573682(-) (comEA) [Staphylococcus aureus subsp. aureus ST398 strain 2012-3]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRDFENKDTALKQSTSENSSLSKLEDVQVKDGDDSK
NKGPVYVDIKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQFGANSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=228950 CAC37_RS07445 WP_001825349.1 1572996..1573682(-) (comEA) [Staphylococcus aureus subsp. aureus ST398 strain 2012-3]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAGATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATGATTCCAAA
AATAAAGGTCCTGTATATGTCGATATAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTAGATGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATTCCTCATAAAGGACAAAAGAATGTTGAACCACAATTTGGAGCAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

96.476

99.561

0.961
  comEA Staphylococcus aureus N315

96.476

99.561

0.961

Multiple sequence alignment