Detailed information    

insolico Bioinformatically predicted

Overview

Name   comK/comK1   Type   Regulator
Locus tag   CAC37_RS04545 Genome accession   NZ_CP021178
Coordinates   955897..956466 (-) Length   189 a.a.
NCBI ID   WP_096002271.1    Uniprot ID   -
Organism   Staphylococcus aureus subsp. aureus ST398 strain 2012-3     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 950897..961466
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CAC37_RS04525 (CAC37_04715) - 952400..953758 (+) 1359 WP_000021872.1 TrkH family potassium uptake protein -
  CAC37_RS04530 (CAC37_04720) - 953897..955408 (+) 1512 WP_000414168.1 bifunctional metallophosphatase/5'-nucleotidase -
  CAC37_RS04545 (CAC37_04735) comK/comK1 955897..956466 (-) 570 WP_096002271.1 competence protein ComK Regulator
  CAC37_RS04550 (CAC37_04740) - 956676..956894 (+) 219 WP_000876826.1 IDEAL domain-containing protein -
  CAC37_RS04555 (CAC37_04745) - 956975..957961 (-) 987 WP_000668814.1 lipoate--protein ligase -
  CAC37_RS04560 (CAC37_04750) - 958160..958336 (+) 177 WP_000214898.1 YkvS family protein -
  CAC37_RS04565 (CAC37_04755) - 958351..958953 (+) 603 WP_001033867.1 type II CAAX prenyl endopeptidase Rce1 family protein -
  CAC37_RS13435 - 959268..959330 (+) 63 WP_240785570.1 putative holin-like toxin -
  CAC37_RS04570 (CAC37_04765) - 959965..960249 (+) 285 WP_000790905.1 lactococcin 972 family bacteriocin -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 22619.86 Da        Isoelectric Point: 9.6091

>NTDB_id=228936 CAC37_RS04545 WP_096002271.1 955897..956466(-) (comK/comK1) [Staphylococcus aureus subsp. aureus ST398 strain 2012-3]
MYSQNIYVIRKGDMVIRPAFDDDDQRNGSEIIRFDKTRIQNPFKVQKIIERSCKFYGNTYLGKKAETNRITGISSKPPIL
LTPLFPTYFFPTHSDRQNENIWLNMHYIESIKELKNRKCKVTFINNESIILHVSYHSLWHQYNNSIFYYYMVDKQSRMIS
KNPDQPIDYNKATMNVFEALTRYSLFEDK

Nucleotide


Download         Length: 570 bp        

>NTDB_id=228936 CAC37_RS04545 WP_096002271.1 955897..956466(-) (comK/comK1) [Staphylococcus aureus subsp. aureus ST398 strain 2012-3]
ATGTATTCTCAAAATATTTATGTGATACGCAAAGGAGACATGGTTATTCGACCAGCATTTGATGATGACGATCAAAGAAA
TGGTAGTGAAATAATTCGGTTTGACAAAACGCGTATTCAAAATCCTTTTAAAGTCCAGAAAATCATTGAACGCTCTTGCA
AATTTTATGGTAATACTTATCTTGGCAAGAAAGCAGAGACAAACCGCATTACTGGCATTTCTAGTAAACCACCTATTTTA
CTAACACCATTATTTCCAACTTATTTTTTCCCAACACATTCTGACAGACAAAATGAAAATATTTGGTTAAATATGCATTA
TATCGAAAGTATCAAAGAATTAAAAAATCGTAAATGTAAAGTGACATTTATTAATAATGAATCAATCATTCTTCATGTTT
CATACCACAGTTTATGGCATCAATATAACAATTCCATTTTTTACTATTACATGGTAGATAAACAATCTCGCATGATATCA
AAAAATCCCGACCAACCAATAGATTATAATAAAGCCACAATGAATGTGTTTGAAGCATTGACACGCTATTCTTTATTTGA
AGATAAATAA

Domains

Predicted by InterproScan.

ComK protein (ComK)

(5-156)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comK/comK1 Staphylococcus aureus MW2

99.471

100

0.995
  comK/comK1 Staphylococcus aureus N315

99.471

100

0.995

Multiple sequence alignment