Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   CAC37_RS02515 Genome accession   NZ_CP021178
Coordinates   540801..541370 (+) Length   189 a.a.
NCBI ID   WP_000872879.1    Uniprot ID   A0A2S6DF07
Organism   Staphylococcus aureus subsp. aureus ST398 strain 2012-3     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 535801..546370
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CAC37_RS02490 (CAC37_02590) cysE 537013..537660 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  CAC37_RS02495 (CAC37_02595) cysS 537644..539044 (+) 1401 WP_000631961.1 cysteine--tRNA ligase -
  CAC37_RS02500 (CAC37_02600) - 539037..539441 (+) 405 WP_000370181.1 Mini-ribonuclease 3 -
  CAC37_RS02505 (CAC37_02605) rlmB 539449..540195 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  CAC37_RS02510 (CAC37_02610) - 540195..540719 (+) 525 WP_000664738.1 NYN domain-containing protein -
  CAC37_RS02515 (CAC37_02615) sigH 540801..541370 (+) 570 WP_000872879.1 sigma-70 family RNA polymerase sigma factor Regulator
  CAC37_RS02520 (CAC37_02620) rpmG 541485..541628 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  CAC37_RS02525 (CAC37_02625) secE 541684..541866 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  CAC37_RS02530 (CAC37_02630) nusG 541879..542427 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  CAC37_RS02535 (CAC37_02635) rplK 542608..543030 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  CAC37_RS02540 (CAC37_02640) rplA 543238..543930 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  CAC37_RS02545 (CAC37_02645) rplJ 544202..544702 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  CAC37_RS02550 (CAC37_02650) rplL 544745..545113 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  CAC37_RS02555 (CAC37_02655) - 545288..545896 (+) 609 WP_000020293.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23097.02 Da        Isoelectric Point: 9.7681

>NTDB_id=228928 CAC37_RS02515 WP_000872879.1 540801..541370(+) (sigH) [Staphylococcus aureus subsp. aureus ST398 strain 2012-3]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGKQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=228928 CAC37_RS02515 WP_000872879.1 540801..541370(+) (sigH) [Staphylococcus aureus subsp. aureus ST398 strain 2012-3]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAAAGCAGCCTTTCACAAATTATGTTCAGTGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2S6DF07

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979

Multiple sequence alignment