Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   C4962_RS09460 Genome accession   NZ_CP026929
Coordinates   1980510..1981166 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain CFS3246     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1975510..1986166
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C4962_RS09430 (C4962_10190) dcyD 1976389..1977375 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  C4962_RS09435 (C4962_10195) tcyL 1977390..1978058 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  C4962_RS09440 (C4962_10200) tcyN 1978055..1978807 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  C4962_RS09445 (C4962_10205) sdiA 1979037..1979759 (+) 723 WP_001154260.1 transcriptional regulator SdiA -
  C4962_RS09450 (C4962_10210) yecF 1979827..1980051 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  C4962_RS09455 (C4962_26280) yecU 1980038..1980214 (-) 177 WP_000590344.1 protein YecU -
  C4962_RS24825 - 1980252..1980368 (-) 117 WP_001302039.1 hypothetical protein -
  C4962_RS09460 (C4962_10220) letA 1980510..1981166 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  C4962_RS09465 (C4962_10225) uvrC 1981163..1982995 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  C4962_RS09470 (C4962_10230) pgsA 1983052..1983600 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  C4962_RS09490 (C4962_10250) yecA 1984249..1984914 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=228840 C4962_RS09460 WP_000611328.1 1980510..1981166(+) (letA) [Escherichia coli strain CFS3246]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=228840 C4962_RS09460 WP_000611328.1 1980510..1981166(+) (letA) [Escherichia coli strain CFS3246]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482

Multiple sequence alignment