Detailed information NTG0228825

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: B5M25_RS04970
• Genome accession: NZ_CP021171
• Coordinates: 969096..970082 (+)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain CHU15-056
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 964096..975082

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
B5M25_RS04945 (B5M25_04890)	opp4B	964310..965272 (+)	963	WP_000915997.1	oligopeptide ABC transporter permease	-
B5M25_RS04950 (B5M25_04895)	opp4C	965284..966165 (+)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
B5M25_RS04955 (B5M25_04900)	trpS	966207..967196 (-)	990	WP_000448934.1	tryptophan--tRNA ligase	-
B5M25_RS04960 (B5M25_04905)	spxA	967490..967885 (+)	396	WP_000258003.1	transcriptional regulator SpxA	-
B5M25_RS04965 (B5M25_04910)	mecA	968256..968975 (+)	720	WP_001217728.1	adaptor protein MecA	-
B5M25_RS04970 (B5M25_04915)	coiA	969096..970082 (+)	987	WP_000959282.1	competence protein CoiA family protein	Machinery gene
B5M25_RS04975 (B5M25_04920)	pepF	970130..971938 (+)	1809	WP_000082725.1	oligoendopeptidase F	-
B5M25_RS04980 (B5M25_04925)	yjbH	972398..973204 (-)	807	WP_000896697.1	protease adaptor protein YjbH	-
B5M25_RS04985 (B5M25_04930)	-	973227..973592 (-)	366	WP_000214070.1	truncated hemoglobin YjbI	-
B5M25_RS04990 (B5M25_04935)	-	973696..974289 (-)	594	WP_000224619.1	CYTH domain-containing protein	-
B5M25_RS04995 (B5M25_04940)	-	974475..974822 (+)	348	WP_001242103.1	hypothetical protein	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=228825 B5M25_RS04970 WP_000959282.1 969096..970082(+) (coiA) [Staphylococcus aureus strain CHU15-056]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=228825 B5M25_RS04970 WP_000959282.1 969096..970082(+) (coiA) [Staphylococcus aureus strain CHU15-056]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976