Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   B5M25_RS02695 Genome accession   NZ_CP021171
Coordinates   540260..540829 (+) Length   189 a.a.
NCBI ID   WP_000872882.1    Uniprot ID   A0A7U7EXA1
Organism   Staphylococcus aureus strain CHU15-056     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 535260..545829
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  B5M25_RS02670 (B5M25_02635) cysE 536473..537120 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  B5M25_RS02675 (B5M25_02640) cysS 537104..538504 (+) 1401 WP_000631969.1 cysteine--tRNA ligase -
  B5M25_RS02680 (B5M25_02645) - 538497..538901 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  B5M25_RS02685 (B5M25_02650) rlmB 538909..539655 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  B5M25_RS02690 (B5M25_02655) - 539655..540179 (+) 525 WP_000664737.1 NYN domain-containing protein -
  B5M25_RS02695 (B5M25_02660) sigH 540260..540829 (+) 570 WP_000872882.1 RNA polymerase sigma factor Regulator
  B5M25_RS02700 (B5M25_02665) rpmG 540944..541087 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  B5M25_RS02705 (B5M25_02670) secE 541143..541325 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  B5M25_RS02710 (B5M25_02675) nusG 541338..541886 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  B5M25_RS02715 (B5M25_02680) rplK 542067..542489 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  B5M25_RS02720 (B5M25_02685) rplA 542697..543389 (+) 693 WP_110228619.1 50S ribosomal protein L1 -
  B5M25_RS02730 (B5M25_02690) rplJ 543661..544161 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  B5M25_RS02735 (B5M25_02695) rplL 544204..544572 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  B5M25_RS02740 (B5M25_02700) - 544747..545355 (+) 609 WP_057485239.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23044.91 Da        Isoelectric Point: 9.4170

>NTDB_id=228819 B5M25_RS02695 WP_000872882.1 540260..540829(+) (sigH) [Staphylococcus aureus strain CHU15-056]
MKYDLTTQDSTIKRNNSINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=228819 B5M25_RS02695 WP_000872882.1 540260..540829(+) (sigH) [Staphylococcus aureus strain CHU15-056]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATTCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EXA1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

100

100

1
  sigH Staphylococcus aureus MW2

97.884

100

0.979

Multiple sequence alignment