Detailed information NTG0228396

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: C4J65_RS13995
• Genome accession: NZ_CP026730
• Coordinates: 3080755..3081879 (+)
• Length: 374 a.a.
• NCBI ID: WP_003975482.1
• Uniprot ID: Q9X8L6
• Organism: Streptomyces sp. CB09001
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3075755..3086879

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C4J65_RS13980 (C4J65_13965)	-	3076002..3076826 (+)	825	WP_115742720.1	hypothetical protein	-
C4J65_RS13985 (C4J65_13970)	-	3077005..3078771 (-)	1767	WP_115742721.1	sigma-70 family RNA polymerase sigma factor	-
C4J65_RS13990 (C4J65_13975)	radA/sms	3079264..3080673 (+)	1410	WP_115742722.1	DNA repair protein RadA	Machinery gene
C4J65_RS13995 (C4J65_13980)	disA	3080755..3081879 (+)	1125	WP_003975482.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
C4J65_RS36055	-	3081916..3082758 (-)	843	WP_162833182.1	hypothetical protein	-
C4J65_RS14010 (C4J65_13995)	-	3082945..3083871 (+)	927	WP_115742725.1	A/G-specific adenine glycosylase	-
C4J65_RS14015 (C4J65_14000)	-	3084161..3084694 (+)	534	WP_003975479.1	SigE family RNA polymerase sigma factor	-
C4J65_RS14020 (C4J65_14005)	-	3084682..3085359 (+)	678	WP_205351008.1	hypothetical protein	-
C4J65_RS14025 (C4J65_14010)	cseB	3085491..3086195 (+)	705	WP_115742727.1	two-component system response regulator CseB	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40043.76 Da
• Isoelectric Point: 5.0058

>NTDB_id=228396 C4J65_RS13995 WP_003975482.1 3080755..3081879(+) (disA) [Streptomyces sp. CB09001]
MAANDRAAAPGKSGGSAGADGLMRASLSAVAPGTSLRDGLERVLRGNTGGLIVLGSDKTVESMCTGGFVLDVEFTATRLR
ELCKLDGGIVLSSDLSKILRAGVQLLPDPTIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALAELDKLSHAELLELSTVARALGYTGSPETLDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=228396 C4J65_RS13995 WP_003975482.1 3080755..3081879(+) (disA) [Streptomyces sp. CB09001]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGAAAGTCCGGTGGGAGTGCCGGTGCCGATGGCCTGATGCGCGCCTCACT
GAGCGCCGTGGCGCCCGGCACCTCCCTGCGCGACGGCCTGGAGCGGGTCCTGCGCGGCAACACCGGCGGTCTGATCGTGC
TGGGTTCCGACAAGACCGTCGAGTCGATGTGCACGGGCGGTTTCGTGCTGGATGTCGAGTTCACCGCGACCCGGCTGCGC
GAGCTGTGCAAGCTCGACGGCGGCATCGTGCTGTCCTCGGACCTGTCGAAGATCCTGCGGGCGGGGGTGCAGCTCCTTCC
GGATCCGACCATTCCGACGGAGGAGACCGGTACGCGGCACCGTACTGCCGACCGGGTGAGCAAGCAGGTCGGCTTCCCCG
TCGTGTCGGTGTCGCAGTCGATGCGGCTGATCGCGTTGTACGTGGACGGGCAGCGGCGGGTGCTGGAGGATTCGGCCGCG
ATTCTGTCGCGGGCCAATCAGGCGCTGGCGACGCTGGAGCGGTACAAGCTGCGCCTCGACGAGGTCGCGGGGACGCTGTC
GGCGTTGGAGATCGAGGACCTGGTGACGGTGCGGGACGTCTCGGCGGTCGCGCAGCGGCTCGAGATGGTGCGCCGGATCG
CCACCGAGATCGCCGAGTACGTGGTGGAGCTGGGGACCGACGGGCGGCTGCTGGCGCTGCAGCTGGACGAGTTGATCGCC
GGTGTGGAGCCGGAGCGCGAGCTGGTCGTGCGGGACTACGTGCCCGAGCCGACCGCGAAGCGCTCGCGGACGGTCGACGA
GGCGCTCGCCGAGCTGGACAAGCTCAGCCATGCCGAGCTGCTGGAGCTGTCCACGGTGGCACGGGCGTTGGGGTACACCG
GGTCGCCCGAGACACTGGACTCCGCGGTGTCGCCGCGCGGGTTCCGGCTGCTGGCCAAGGTGCCGCGGCTGCCGGGCGCG
ATCATCGACCGGCTGGTGGAGCACTTCGGCGGCCTGCAGAAGCTGCTCGCCGCCAGTGTCGACGACCTCCAGACGGTGGA
CGGCGTCGGTGAGGCGCGGGCGCGCAGCGTGCGGGAGGGGCTGTCGCGGCTGGCGGAGTCGTCGATCCTGGAGCGCTACG
TCTGA

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

3D structure

• AlphaFold DB: Q9X8L6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	46.26	96.524	0.447