Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   MW_RS08625 Genome accession   NC_003923
Coordinates   1745162..1746424 (-) Length   420 a.a.
NCBI ID   WP_000472304.1    Uniprot ID   Q8NW72
Organism   Staphylococcus aureus subsp. aureus MW2     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1740162..1751424
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MW_RS08600 (MW1613) - 1740360..1741028 (-) 669 WP_000805950.1 uroporphyrinogen-III synthase -
  MW_RS08605 (MW1614) hemC 1741050..1741976 (-) 927 WP_001230226.1 hydroxymethylbilane synthase -
  MW_RS08610 (MW1615) ccsA 1742018..1742833 (-) 816 WP_001157329.1 cytochrome c biogenesis protein -
  MW_RS08615 (MW1616) hemA 1742855..1744201 (-) 1347 WP_000545451.1 glutamyl-tRNA reductase -
  MW_RS08620 (MW1617) yihA 1744418..1745008 (-) 591 WP_000867701.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  MW_RS08625 (MW1618) clpX 1745162..1746424 (-) 1263 WP_000472304.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  MW_RS08630 (MW1619) tig 1746575..1747876 (-) 1302 WP_000127573.1 trigger factor -
  MW_RS08635 - 1747924..1748034 (-) 111 WP_001790560.1 hypothetical protein -
  MW_RS08640 (MW1620) - 1748039..1748968 (-) 930 WP_001280022.1 hypothetical protein -
  MW_RS08645 (MW1621) - 1748987..1749595 (-) 609 WP_000032650.1 NUDIX domain-containing protein -
  MW_RS08655 (MW1622) rplT 1749737..1750093 (-) 357 WP_001138360.1 50S ribosomal protein L20 -
  MW_RS08660 (MW1623) rpmI 1750140..1750340 (-) 201 WP_001125540.1 50S ribosomal protein L35 -
  MW_RS08665 (MW1624) infC 1750369..1750896 (-) 528 WP_001791162.1 translation initiation factor IF-3 -

Sequence

Protein


Download         Length: 420 a.a.        Molecular weight: 46296.49 Da        Isoelectric Point: 4.2827

>NTDB_id=22724 MW_RS08625 WP_000472304.1 1745162..1746424(-) (clpX) [Staphylococcus aureus subsp. aureus MW2]
MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAMTELPTPKEIMDHLNEYVIGQEK
AKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENIL
LRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTN
ILFILGGAFDGIEEVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNIL
TQPKNALVKQYTKMLELDNVDLEFTEEALSAISEKAIERKTGARGLRSIIEESLIDIMFDVPSNENVTKVVITAQTINEE
TEPELYDAEGNLINNSKTSA

Nucleotide


Download         Length: 1263 bp        

>NTDB_id=22724 MW_RS08625 WP_000472304.1 1745162..1746424(-) (clpX) [Staphylococcus aureus subsp. aureus MW2]
ATGTTTAAATTCAATGAAGATGAAGAAAATTTGAAATGCTCTTTCTGCGGAAAAGACCAAGATCAAGTAAAAAAACTTGT
AGCAGGAAGTGGTGTATATATTTGTAATGAGTGTATTGAATTATGCTCAGAAATCGTCGAAGAAGAATTAGCTCAAAACA
CTTCTGAAGCGATGACAGAATTACCTACTCCTAAAGAAATTATGGATCATTTAAACGAATATGTTATTGGTCAAGAAAAA
GCTAAAAAATCTTTAGCTGTAGCTGTTTATAACCACTATAAGCGTATTCAACAATTAGGACCAAAAGAAGATGATGTTGA
ATTACAAAAAAGTAACATTGCATTAATTGGGCCAACAGGTAGTGGTAAAACATTATTAGCTCAAACATTAGCCAAGACGT
TGAATGTACCATTTGCAATTGCAGATGCGACAAGTTTAACTGAAGCTGGTTATGTAGGCGATGATGTTGAAAATATCTTG
TTGAGATTAATTCAAGCAGCTGACTTTGACATTGATAAAGCCGAAAAAGGTATTATTTATGTAGATGAAATTGATAAAAT
TGCACGTAAATCTGAAAACACATCTATAACACGTGACGTTTCAGGTGAAGGTGTTCAACAAGCATTGCTTAAAATCTTAG
AAGGTACGACTGCAAGTGTTCCGCCACAAGGTGGACGCAAACATCCAAACCAAGAAATGATTCAAATTGATACAACAAAT
ATCTTATTTATTCTTGGTGGTGCCTTTGATGGTATTGAAGAAGTGATTAAGCGCCGTCTTGGTGAAAAAGTTATTGGTTT
CTCAAGCAATGAAGCTGATAAATATGACGAACAAGCATTATTAGCACAAATTCGCCCAGAAGATTTGCAAGCCTATGGTT
TGATTCCTGAATTTATCGGACGTGTGCCAATTGTAGCTAATTTAGAAACATTAGATGTAACTGCGTTGAAAAACATCTTA
ACGCAACCTAAAAATGCACTTGTGAAACAATATACTAAAATGCTGGAATTAGATAATGTGGATTTAGAGTTCACTGAAGA
AGCTTTATCAGCAATTAGTGAAAAAGCAATTGAAAGAAAAACAGGTGCGCGTGGTTTACGTTCAATCATAGAAGAATCGT
TAATCGATATTATGTTTGATGTGCCTTCTAACGAAAATGTAACGAAGGTAGTTATTACAGCACAAACAATTAATGAAGAA
ACTGAACCAGAACTATACGACGCAGAAGGCAATTTAATTAATAATAGTAAAACATCAGCTTAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-305)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8NW72

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

66.917

95

0.636
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.456

94.048

0.531

Multiple sequence alignment