Detailed information NTG0227058

Bioinformatically predicted

Overview

• Name: cytR
• Type: Regulator
• Locus tag: C2Q99_RS21350
• Genome accession: NZ_CP026361
• Coordinates: 4123440..4124465 (-)
• Length: 341 a.a.
• NCBI ID: WP_000644904.1
• Uniprot ID: P0ACN8
• Organism: Escherichia coli strain 1A
• Function: promote competence gene expression (predicted from homology) Competence regulation

Genomic Context

Location: 4118440..4129465

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C2Q99_RS21320	zapB	4118524..4118769 (+)	246	WP_001296623.1	septal ring assembly protein ZapB	-
C2Q99_RS21325	rraA	4118854..4119339 (-)	486	WP_000872908.1	ribonuclease E activity regulator RraA	-
C2Q99_RS21330	menA	4119432..4120358 (-)	927	WP_000139496.1	1,4-dihydroxy-2-naphthoate polyprenyltransferase	-
C2Q99_RS21335	hslU	4120425..4121756 (-)	1332	WP_001293341.1	HslU--HslV peptidase ATPase subunit	-
C2Q99_RS21340	hslV	4121766..4122296 (-)	531	WP_000208242.1	ATP-dependent protease subunit HslV	-
C2Q99_RS21345	ftsN	4122389..4123348 (-)	960	WP_000068828.1	cell division protein FtsN	-
C2Q99_RS21350	cytR	4123440..4124465 (-)	1026	WP_000644904.1	DNA-binding transcriptional regulator CytR	Regulator
C2Q99_RS21355	priA	4124621..4126819 (-)	2199	WP_001301269.1	primosomal protein N'	Machinery gene
C2Q99_RS21360	rpmE	4127022..4127234 (+)	213	WP_000710769.1	50S ribosomal protein L31	-
C2Q99_RS21365	yiiX	4127295..4127903 (-)	609	WP_000797353.1	YiiX family permuted papain-like enzyme	-
C2Q99_RS21370	metJ	4128087..4128404 (-)	318	WP_000852812.1	met regulon transcriptional regulator MetJ	-

Sequence

Protein

• Length: 341 a.a.
• Molecular weight: 37819.78 Da
• Isoelectric Point: 6.3842

>NTDB_id=227058 C2Q99_RS21350 WP_000644904.1 4123440..4124465(-) (cytR) [Escherichia coli strain 1A]
MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRVEKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDP
FFSEIIRGIEVTAANHGYLVLIGDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVDPQYIARGDFTFEAGSKAMQQLL
DLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLSIIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHV
GSGSRLMDCELIIRGSTRALP

Nucleotide

• Length: 1026 bp

>NTDB_id=227058 C2Q99_RS21350 WP_000644904.1 4123440..4124465(-) (cytR) [Escherichia coli strain 1A]
GTGAAAGCGAAGAAGCAGGAAACTGCCGCGACCATGAAAGACGTTGCCCTCAAGGCAAAAGTCTCTACAGCGACCGTCTC
CCGAGCATTAATGAATCCCGATAAAGTCTCCCAGGCCACCCGTAATCGGGTTGAAAAAGCGGCCCGGGAAGTGGGTTATT
TACCGCAGCCTATGGGGCGCAACGTCAAGCGTAATGAATCCCGCACCATTCTGGTGATTGTCCCGGATATCTGCGATCCC
TTCTTTAGCGAAATTATTCGCGGTATCGAAGTTACGGCGGCAAATCACGGATATCTGGTGCTGATTGGCGACTGTGCGCA
TCAAAATCAGCAGGAAAAAACCTTTATCGATTTGATCATCACCAAGCAAATTGATGGCATGTTGTTGCTGGGTTCAAGGC
TGCCGTTTGATGCCAGCATTGAGGAACAGCGTAATCTGCCGCCGATGGTGATGGCGAACGAATTTGCACCGGAGCTGGAG
CTGCCTACAGTTCATATCGACAATCTGACCGCCGCATTTGATGCAGTAAATTATTTATATGAGCAAGGGCATAAACGGAT
TGGCTGTATAGCCGGTCCCGAAGAGATGCCGCTGTGTCACTACCGCCTGCAAGGCTATGTTCAGGCGCTGCGTCGCTGCG
GCATTATGGTTGATCCGCAATACATCGCCCGTGGCGACTTCACCTTCGAAGCCGGAAGCAAAGCGATGCAGCAGCTGCTT
GATCTTCCACAACCGCCTACTGCTGTCTTCTGCCATAGCGATGTGATGGCGCTCGGCGCACTTTCTCAGGCAAAACGCCA
GGGGCTGAAAGTCCCGGAAGACCTTTCCATAATCGGTTTTGATAACATCGACCTGACGCAATTTTGTGATCCGCCGCTGA
CAACCATCGCGCAGCCGCGTTACGAAATCGGTCGGGAAGCTATGCTGTTATTGCTTGATCAAATGCAGGGGCAACACGTT
GGCAGTGGCTCTCGTTTAATGGACTGCGAACTTATCATCCGGGGATCAACACGCGCGTTACCTTAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (11-56)

• Periplasmic binding protein-like domain (Peripla_BP_3) (176-337)

3D structure

• AlphaFold DB: P0ACN8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cytR	Vibrio parahaemolyticus RIMD 2210633	64.179	98.24	0.63
cytR	Vibrio cholerae C6706	65.443	95.894	0.628