Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   C2R14_RS10540 Genome accession   NZ_CP026349
Coordinates   1994703..1995359 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain 6A     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1989703..2000359
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C2R14_RS10510 yecA 1990954..1991619 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  C2R14_RS10530 pgsA 1992269..1992817 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  C2R14_RS10535 uvrC 1992874..1994706 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  C2R14_RS10540 letA 1994703..1995359 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  C2R14_RS24830 - 1995501..1995572 (+) 72 Protein_1951 transcriptional regulator -
  C2R14_RS24190 yecU 1995655..1995831 (+) 177 WP_000590347.1 protein YecU -
  C2R14_RS10545 yecF 1995818..1996042 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  C2R14_RS10550 sdiA 1996110..1996832 (-) 723 WP_001152715.1 transcriptional regulator SdiA -
  C2R14_RS10555 tcyN 1997062..1997814 (-) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  C2R14_RS10560 tcyL 1997811..1998479 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  C2R14_RS10565 dcyD 1998494..1999480 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=226025 C2R14_RS10540 WP_000611335.1 1994703..1995359(-) (letA) [Escherichia coli strain 6A]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=226025 C2R14_RS10540 WP_000611335.1 1994703..1995359(-) (letA) [Escherichia coli strain 6A]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486

Multiple sequence alignment