Detailed information NTG0225823

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: B5P37_RS01855
• Genome accession: NZ_CP020773
• Coordinates: 359771..360814 (-)
• Length: 347 a.a.
• NCBI ID: WP_085236502.1
• Uniprot ID: A0AAC9RN34
• Organism: Staphylococcus lutrae strain ATCC 700373
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 354771..365814

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
B5P37_RS01825 (B5P37_01825)	-	355671..355874 (-)	204	WP_085238397.1	DUF1128 family protein	-
B5P37_RS01830 (B5P37_01830)	-	356007..356465 (+)	459	WP_085236491.1	low molecular weight protein-tyrosine-phosphatase	-
B5P37_RS01835 (B5P37_01835)	-	356473..356760 (+)	288	WP_085236494.1	YtxH domain-containing protein	-
B5P37_RS01840 (B5P37_01840)	-	356977..358299 (+)	1323	WP_085236496.1	YihY/virulence factor BrkB family protein	-
B5P37_RS01845 (B5P37_01845)	-	358328..358909 (+)	582	WP_085236498.1	carbonic anhydrase	-
B5P37_RS01850 (B5P37_01850)	vraR	359152..359781 (-)	630	WP_085236500.1	response regulator transcription factor	Regulator
B5P37_RS01855 (B5P37_01855)	vraS	359771..360814 (-)	1044	WP_085236502.1	sensor histidine kinase	Regulator
B5P37_RS01860 (B5P37_01860)	liaF	360811..361512 (-)	702	WP_085236504.1	cell wall-active antibiotics response protein LiaF	-
B5P37_RS01865 (B5P37_01865)	-	361525..361914 (-)	390	WP_085236506.1	hypothetical protein	-
B5P37_RS01870 (B5P37_01870)	map	362013..362777 (-)	765	WP_085236508.1	type I methionyl aminopeptidase	-
B5P37_RS01875 (B5P37_01875)	-	362873..363871 (+)	999	WP_085236510.1	aromatic acid exporter family protein	-
B5P37_RS01880 (B5P37_01880)	-	364049..365554 (-)	1506	WP_244898625.1	exo-alpha-sialidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39766.26 Da
• Isoelectric Point: 6.0552

>NTDB_id=225823 B5P37_RS01855 WP_085236502.1 359771..360814(-) (vraS) [Staphylococcus lutrae strain ATCC 700373]
MNHYVRAIGSMLILVYSMLTTFFFIDKVFTNIIYFQGMFYTQILGIPVFIFLNLVVIFLCIIVGSVLAYKINQQNDWLKQ
QIERAFEGETVGINDQQIELYNETIELYQALVPLNQSLHKMRIKTQNLTNESYNLNDLKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETELAPPLDQQIPTLEKMIQDSQLEMRALLLHLRPIGLKNKSLGEGIKSLVTDLQRKVPMKVVQEI
DEIEVPKGIEDHLFRITQEAISNTLRHAKGTQVTVELLKLKDHLLLRIQDDGIGFNVNDQLEQSYGLKNMQERAIEIGAT
LHIVSLPDAGTRIEVKAPLEKEAKHDS

Nucleotide

• Length: 1044 bp

>NTDB_id=225823 B5P37_RS01855 WP_085236502.1 359771..360814(-) (vraS) [Staphylococcus lutrae strain ATCC 700373]
ATGAATCATTACGTCCGAGCCATTGGATCGATGTTAATACTCGTTTACAGTATGTTAACGACGTTCTTTTTTATTGATAA
AGTTTTTACTAACATTATTTATTTCCAGGGGATGTTTTATACACAAATTTTAGGGATACCGGTTTTCATATTTTTAAACT
TAGTCGTTATCTTTTTGTGTATTATCGTTGGGAGTGTGCTTGCTTATAAAATTAATCAACAAAACGATTGGCTCAAACAA
CAAATTGAGCGCGCATTTGAAGGTGAGACGGTAGGGATTAATGACCAACAAATTGAACTCTATAATGAAACCATTGAACT
TTATCAAGCATTGGTTCCTCTTAATCAGTCCCTTCATAAAATGCGAATTAAAACTCAAAATTTAACGAATGAATCATATA
ATTTAAATGATTTGAAGGTGAAAAAAATAATTGAAGATGAGCGACAAAGGCTCGCACGTGAATTGCATGACAGTGTCTCT
CAACAGCTTTTTGCAGCTAGTATGATGTTGTCTGCGATTAAAGAAACGGAATTAGCGCCACCCCTTGATCAACAAATTCC
AACACTTGAGAAAATGATTCAAGATTCACAGTTGGAGATGCGTGCGTTGTTGCTTCATTTGAGACCGATTGGATTAAAAA
ATAAATCACTCGGTGAGGGGATTAAATCGCTTGTGACAGATTTACAGCGGAAAGTTCCGATGAAAGTCGTTCAAGAAATT
GATGAAATTGAAGTGCCAAAAGGGATTGAAGATCATTTGTTTAGAATTACACAAGAAGCGATTTCCAATACATTACGCCA
TGCGAAAGGGACTCAAGTGACGGTTGAATTATTAAAACTTAAAGATCATTTGTTGCTCCGTATTCAAGATGATGGGATTG
GATTTAATGTGAATGATCAATTGGAACAAAGTTATGGTTTAAAAAATATGCAAGAGCGTGCCATTGAAATTGGAGCGACA
TTGCATATTGTGTCATTGCCCGATGCAGGAACAAGAATTGAAGTCAAAGCACCACTTGAAAAGGAGGCTAAACATGACAG
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-341)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	81.792	99.712	0.816