Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   B7P03_RS09365 Genome accession   NZ_CP020618
Coordinates   1878187..1878816 (-) Length   209 a.a.
NCBI ID   WP_002450048.1    Uniprot ID   A0A1L8Y4G9
Organism   Staphylococcus hominis subsp. hominis strain K1     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1873187..1883816
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  B7P03_RS09335 (B7P03_09265) - 1873884..1874417 (-) 534 WP_087436988.1 acyl-CoA thioesterase -
  B7P03_RS09340 (B7P03_09270) - 1874450..1875697 (-) 1248 WP_087436989.1 aminopeptidase -
  B7P03_RS09345 (B7P03_09275) - 1875709..1875915 (-) 207 WP_002450082.1 DUF1128 domain-containing protein -
  B7P03_RS09350 (B7P03_09280) - 1876057..1876521 (+) 465 WP_002455129.1 low molecular weight protein-tyrosine-phosphatase -
  B7P03_RS09355 (B7P03_09285) - 1876527..1876808 (+) 282 WP_002450075.1 hypothetical protein -
  B7P03_RS09360 (B7P03_09290) - 1876941..1878107 (+) 1167 WP_087436990.1 YihY/virulence factor BrkB family protein -
  B7P03_RS09365 (B7P03_09295) vraR 1878187..1878816 (-) 630 WP_002450048.1 two-component system response regulator VraR Regulator
  B7P03_RS09370 (B7P03_09300) vraS 1878818..1879852 (-) 1035 WP_049415634.1 sensor histidine kinase Regulator
  B7P03_RS09375 (B7P03_09305) liaF 1879849..1880550 (-) 702 WP_087436991.1 cell wall-active antibiotics response protein LiaF -
  B7P03_RS09380 (B7P03_09310) - 1880571..1880957 (-) 387 WP_087436992.1 hypothetical protein -
  B7P03_RS09385 (B7P03_09315) - 1881185..1882195 (+) 1011 WP_087436993.1 HoxN/HupN/NixA family nickel/cobalt transporter -
  B7P03_RS09390 (B7P03_09320) map 1882244..1882996 (-) 753 WP_002450057.1 type I methionyl aminopeptidase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23592.26 Da        Isoelectric Point: 5.3673

>NTDB_id=225045 B7P03_RS09365 WP_002450048.1 1878187..1878816(-) (vraR) [Staphylococcus hominis subsp. hominis strain K1]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGSSGKEAIEKAHTLNPDLILMDLLMNDMDGVEATTQIKKDLPHIKVV
MLTSFIEDKEVYRALDAGVDSYILKTTSASDIAEAVRKTYRGESVFEPEVLVKMRNRMKKKAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=225045 B7P03_RS09365 WP_002450048.1 1878187..1878816(-) (vraR) [Staphylococcus hominis subsp. hominis strain K1]
ATGACGATTAAAGTATTATTTGTAGATGATCATGAAATGGTTAGAATTGGTATTTCAAGTTATTTATCTACTCAATCTGA
TATTGAAGTAGTAGGGGAAGGATCATCAGGAAAAGAGGCAATTGAAAAAGCACATACGTTAAATCCTGATTTAATTTTAA
TGGATTTGTTAATGAATGATATGGACGGTGTAGAAGCGACGACACAAATAAAAAAAGATTTGCCTCACATCAAAGTAGTC
ATGTTAACAAGTTTTATAGAAGATAAAGAAGTATATAGGGCACTTGATGCAGGGGTTGATAGTTATATATTAAAAACGAC
AAGTGCAAGTGATATTGCAGAAGCAGTTAGAAAAACATATCGTGGAGAATCTGTATTTGAGCCAGAAGTTTTAGTAAAAA
TGAGAAATAGAATGAAGAAGAAAGCAGAATTATATGAAATGCTCACTGAACGTGAAATGGAAATATTGTTATTAATTGCT
AAAGGCTATTCTAATCAAGAAATTGCCAGTGCTTCACATATTACAATTAAAACAGTAAAAACACATGTGAGTAATATTTT
AAGTAAACTAGAGGTACAAGATAGAACACAAGCGGTTATTTATGCATTCCAACATAATTTAATTCAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1L8Y4G9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

94.737

100

0.947
  degU Bacillus subtilis subsp. subtilis str. 168

35.268

100

0.378

Multiple sequence alignment