Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   C1703_RS21675 Genome accession   NZ_CP026121
Coordinates   4699188..4699853 (+) Length   221 a.a.
NCBI ID   WP_114254445.1    Uniprot ID   -
Organism   Streptomyces sp. Go-475     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4694188..4704853
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C1703_RS21655 (C1703_21400) - 4694501..4695709 (+) 1209 WP_114254442.1 acyltransferase -
  C1703_RS21660 (C1703_21405) - 4695702..4697075 (+) 1374 WP_114254443.1 sensor histidine kinase -
  C1703_RS21665 (C1703_21410) vraR 4697072..4697755 (+) 684 WP_114254444.1 response regulator transcription factor Regulator
  C1703_RS21670 (C1703_21415) - 4697878..4699191 (+) 1314 WP_114257529.1 histidine kinase -
  C1703_RS21675 (C1703_21420) vraR 4699188..4699853 (+) 666 WP_114254445.1 response regulator transcription factor Regulator
  C1703_RS21680 (C1703_21425) - 4699917..4701125 (+) 1209 WP_114254446.1 cytochrome P450 -
  C1703_RS21685 (C1703_21430) - 4701211..4701804 (+) 594 WP_114254447.1 Uma2 family endonuclease -
  C1703_RS21690 (C1703_21435) - 4701805..4703403 (-) 1599 WP_114254448.1 ABC transporter permease -
  C1703_RS21695 (C1703_21440) - 4703400..4704296 (-) 897 WP_114254449.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23862.61 Da        Isoelectric Point: 4.6488

>NTDB_id=224780 C1703_RS21675 WP_114254445.1 4699188..4699853(+) (vraR) [Streptomyces sp. Go-475]
MTIRVLIADDQMMVREGFSVLLNAMPDIEVVGEAVNGREAVAKVRELAPDVVLMDIRMPELNGIEATREIVAADGAAKVL
VLTTFDLDEYVYQALRAGASGFLLKDASARQLADGVRVVASGEALLAPSVTRRLITEFSKLSETPRLMPSAQAAYGDLTD
RETEVLVLIAQGLSNAEIAERLVVAESTIKTHVSRILVKLGLRDRTQAAVFAYEARLVTPG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=224780 C1703_RS21675 WP_114254445.1 4699188..4699853(+) (vraR) [Streptomyces sp. Go-475]
ATGACCATCCGGGTCCTGATCGCGGACGACCAGATGATGGTCCGCGAGGGCTTCTCGGTCCTGCTGAACGCGATGCCGGA
CATCGAGGTCGTCGGCGAGGCGGTGAACGGCCGGGAGGCCGTCGCCAAGGTCCGCGAGCTCGCCCCGGACGTCGTGCTCA
TGGACATCCGCATGCCCGAGCTGAACGGCATCGAGGCGACCCGCGAGATCGTCGCCGCCGACGGCGCGGCGAAGGTCCTG
GTCCTCACGACGTTCGACCTCGACGAGTACGTGTACCAGGCGTTGCGCGCGGGAGCCTCCGGCTTCCTCCTCAAGGACGC
CTCGGCCCGCCAGCTCGCCGACGGGGTGCGGGTCGTGGCGTCCGGGGAGGCGCTGCTGGCGCCCTCGGTGACCAGGAGGC
TGATCACCGAGTTCTCCAAGCTCTCCGAGACCCCGCGCCTGATGCCCTCCGCCCAGGCGGCGTACGGCGACCTCACCGAC
CGGGAGACGGAGGTGCTGGTCCTCATCGCGCAGGGCCTGTCGAACGCGGAGATCGCCGAGCGGCTGGTCGTCGCCGAGTC
GACGATCAAGACGCACGTCAGCCGGATCCTGGTGAAGCTGGGCCTCAGGGACCGCACGCAGGCGGCGGTGTTCGCCTACG
AGGCGCGGCTGGTGACCCCCGGCTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-114)

Bacterial regulatory proteins, luxR family (GerE)

(158-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.954

98.643

0.443
  degU Bacillus subtilis subsp. subtilis str. 168

42.857

98.19

0.421

Multiple sequence alignment