Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   C1703_RS04935 Genome accession   NZ_CP026121
Coordinates   1095348..1096010 (+) Length   220 a.a.
NCBI ID   WP_114250725.1    Uniprot ID   -
Organism   Streptomyces sp. Go-475     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1090348..1101010
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C1703_RS04910 (C1703_04860) mug 1091369..1091914 (+) 546 WP_114250721.1 G/U mismatch-specific DNA glycosylase -
  C1703_RS04915 (C1703_04865) - 1091919..1092350 (-) 432 WP_114250722.1 hypothetical protein -
  C1703_RS04920 (C1703_04870) - 1092406..1093131 (-) 726 WP_114250723.1 ABC transporter permease -
  C1703_RS04925 (C1703_04875) - 1093134..1094054 (-) 921 WP_114250724.1 ABC transporter ATP-binding protein -
  C1703_RS04930 (C1703_04880) - 1094163..1095333 (+) 1171 Protein_984 histidine kinase -
  C1703_RS04935 (C1703_04885) vraR 1095348..1096010 (+) 663 WP_114250725.1 response regulator transcription factor Regulator
  C1703_RS04940 (C1703_04890) - 1096100..1097254 (+) 1155 WP_114250726.1 ROK family transcriptional regulator -
  C1703_RS04945 (C1703_04895) - 1097352..1098110 (-) 759 WP_114250727.1 GntR family transcriptional regulator -
  C1703_RS04950 (C1703_04900) sigJ 1098334..1099164 (-) 831 WP_114250728.1 RNA polymerase sigma factor SigJ -
  C1703_RS04955 (C1703_04905) - 1099274..1099927 (+) 654 WP_114250729.1 NAD(P)-binding domain-containing protein -
  C1703_RS04960 (C1703_04910) - 1100033..1100863 (+) 831 WP_114250730.1 alpha/beta fold hydrolase -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23496.09 Da        Isoelectric Point: 4.8664

>NTDB_id=224747 C1703_RS04935 WP_114250725.1 1095348..1096010(+) (vraR) [Streptomyces sp. Go-475]
MPVTVLLVDDEPLVRAGLRAVLEAQPDIEVVGEAADGAAVIPLVRQLRPDVVAMDVRMPLLDGIEATRALLRTVDEPPRI
LVVTTFENDEYVYEALRAGADGFLLKRARPAEIVHAVRLIAEGESLLFPASVRQLAAAYGEGGGNRAARAAMERAQLTER
EAEVLRLMARGLSNAEIAARLVVGTETVKSHVSSVLAKLGARDRTQAVIAAYESGFVAPG

Nucleotide


Download         Length: 663 bp        

>NTDB_id=224747 C1703_RS04935 WP_114250725.1 1095348..1096010(+) (vraR) [Streptomyces sp. Go-475]
ATGCCGGTCACCGTTCTCCTCGTCGACGACGAACCCCTCGTGCGCGCGGGTCTGCGGGCCGTGCTGGAGGCGCAGCCCGA
CATCGAGGTCGTCGGGGAGGCCGCGGACGGTGCGGCGGTGATCCCGCTGGTGCGGCAGCTGCGGCCGGACGTGGTCGCCA
TGGACGTCCGGATGCCGCTGCTGGACGGCATCGAGGCCACCCGGGCGCTGCTGCGGACGGTCGACGAGCCGCCGCGGATC
CTGGTGGTGACGACCTTCGAGAACGACGAGTACGTGTACGAGGCGCTGCGCGCGGGTGCCGACGGGTTTCTGCTGAAGCG
GGCCCGGCCGGCCGAGATCGTGCACGCGGTGCGGCTGATCGCCGAGGGCGAGTCGCTGCTGTTCCCGGCCTCGGTGCGGC
AGCTGGCCGCCGCGTACGGCGAGGGCGGCGGGAACCGCGCGGCGCGGGCCGCGATGGAGCGGGCCCAGCTGACCGAGCGG
GAGGCGGAGGTGCTGCGGCTGATGGCCCGGGGATTGTCGAACGCGGAGATCGCGGCCCGGCTGGTCGTCGGGACGGAGAC
CGTGAAGTCGCACGTCAGCTCCGTGCTGGCGAAGCTGGGCGCCCGGGACCGCACCCAGGCGGTGATCGCCGCGTACGAGT
CGGGGTTCGTGGCGCCGGGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-118)

Bacterial regulatory proteins, luxR family (GerE)

(156-210)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.284

99.091

0.409
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.368

Multiple sequence alignment