Detailed information NTG0224543

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: C2E46_RS10940
• Genome accession: NZ_CP026082
• Coordinates: 2190943..2193519 (-)
• Length: 858 a.a.
• NCBI ID: WP_161501967.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain YZ1605
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2185943..2198519

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C2E46_RS10915 (C2E46_11335)	-	2186054..2186605 (-)	552	WP_000817341.1	DNA-3-methyladenine glycosylase I	-
C2E46_RS10920 (C2E46_11340)	ruvA	2186628..2187218 (-)	591	WP_000272490.1	Holliday junction branch migration protein RuvA	Machinery gene
C2E46_RS10925 (C2E46_11345)	-	2187220..2188452 (-)	1233	WP_000657483.1	MFS transporter	-
C2E46_RS10930 (C2E46_11350)	hexB	2188484..2190457 (-)	1974	WP_000034613.1	DNA mismatch repair endonuclease MutL	Machinery gene
C2E46_RS10935 (C2E46_11360)	-	2190683..2190886 (+)	204	WP_000191849.1	cold-shock protein	-
C2E46_RS10940 (C2E46_11365)	hexA	2190943..2193519 (-)	2577	WP_161501967.1	DNA mismatch repair protein MutS	Machinery gene
C2E46_RS10945 (C2E46_11370)	argR	2193576..2194013 (-)	438	WP_001033152.1	arginine repressor	-
C2E46_RS10950 (C2E46_11375)	argS	2194235..2195926 (+)	1692	WP_000379861.1	arginine--tRNA ligase	-
C2E46_RS10955 (C2E46_11380)	-	2196014..2196322 (+)	309	WP_001138859.1	bacteriocin immunity protein	-
C2E46_RS10960 (C2E46_11385)	-	2196349..2197221 (-)	873	WP_000915474.1	YitT family protein	-
C2E46_RS10965 (C2E46_11390)	-	2197329..2198273 (-)	945	WP_000857770.1	YitT family protein	-

Sequence

Protein

• Length: 858 a.a.
• Molecular weight: 97053.69 Da
• Isoelectric Point: 4.8471

>NTDB_id=224543 C2E46_RS10940 WP_161501967.1 2190943..2193519(-) (hexA) [Streptococcus agalactiae strain YZ1605]
MAKPTISPGMQQYLDIKENYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNAEKPIPMAGVPYHSAQQYIDVLV
ELGYKVAIAEQMEDPKKAVGVVKREVVQVVTPGTVVESTKPDSANNFLVAIDSQDQQTFGLAYMDVSTGEFQATLLTDFE
SVRSEILNLKAREIVVGYQLTDEKNHLLTKQMNLLLSYEDERLKDIHLIDEQLTDLEISAAEKLLQYVHRTQKRELSHLQ
KVVHYEIKDYLQMSYATKNSLDLLENARTSKKHGSLYWLLDETKTAMGTRMLRTWIDRPLVSMNRIKERQDIIQVFLDYF
FERNDLTESLKGVYDIERLASRVSFGKANPKDLLQLGQTLSQIPRIKMILQSFNQPELDIIVNKIDTMPELESLINTAIA
PEAQATITEGNIIKSGFDKQLDNYRTVMREGTGWIADIEAKERAASGIGTLKIDYNKKDGYYFHVTNSNLSLVPEHFFRK
ATLKNSERYGTAELAKIEGEMLEAREQSSNLEYDIFMRVRAQVESYIKRLQELAKTIATVDVLQSLAVVAENHHYVRPKF
NDEHQIKIKNGRHATVEKVMGVQEYIPNSIYFDSQTDIQLITGPNMSGKSTYMRQLALTVIMAQMGGFVSADEVDLPVFD
AIFTRIGAADDLISGQSTFMVEMMEANQAVKRASDKSLILFDELGRGTATYDGMALAQSIIEYIHDRVRAKTMFATHYHE
LTDLSEQLTRLVNVHVATLERDGEVTFLHKIESGPADKSYGIHVAKIAGLPIDLLDRATDVLSQLEADAVQLIVSPSQEA
VTADLNEELDSEKQQGQLSLFEEPSNAGRVIEELEAIDIMNLTPMQAMNAIFDLKKLL

Nucleotide

• Length: 2577 bp

>NTDB_id=224543 C2E46_RS10940 WP_161501967.1 2190943..2193519(-) (hexA) [Streptococcus agalactiae strain YZ1605]
ATGGCCAAGCCAACGATATCACCGGGAATGCAACAGTATCTGGATATAAAAGAGAATTATCCAGATGCTTTTTTGCTTTT
TAGAATGGGTGATTTTTATGAATTATTTTATGATGATGCGGTAAAAGCAGCACAAATCCTGGAAATTAGCTTGACTAGTC
GAAATAAGAACGCAGAAAAGCCAATCCCAATGGCAGGAGTTCCCTATCACTCAGCTCAACAGTATATTGACGTTTTAGTT
GAATTAGGTTACAAAGTAGCCATTGCTGAGCAGATGGAAGATCCTAAAAAAGCTGTGGGAGTGGTCAAGCGTGAGGTAGT
GCAAGTTGTTACCCCAGGAACGGTTGTGGAGTCAACGAAGCCGGATAGTGCTAATAATTTCTTAGTAGCGATTGATTCGC
AAGATCAACAAACATTTGGTCTAGCATATATGGATGTCTCAACTGGAGAGTTTCAGGCAACCCTTTTAACAGATTTTGAG
TCCGTCCGTAGCGAAATACTAAATTTAAAAGCTCGTGAGATTGTAGTAGGATATCAATTGACGGACGAAAAAAATCACCT
ACTGACGAAGCAGATGAACTTGCTTTTATCATACGAAGACGAACGACTTAAAGATATTCATTTGATTGATGAGCAGTTAA
CTGATTTGGAAATATCTGCTGCGGAAAAACTTTTACAATATGTGCATAGAACACAAAAGCGTGAACTTAGTCATTTACAG
AAAGTAGTTCATTATGAAATAAAGGACTATTTACAAATGTCATATGCAACGAAAAATAGTCTAGATTTACTGGAGAATGC
TAGAACAAGCAAGAAGCACGGAAGTCTTTACTGGTTGTTAGATGAGACTAAAACAGCGATGGGAACTCGAATGCTGAGAA
CTTGGATTGACAGGCCTTTGGTAAGTATGAATCGAATCAAGGAACGTCAAGATATTATTCAAGTGTTTCTTGATTATTTT
TTTGAGAGAAACGATCTCACAGAAAGTTTAAAGGGTGTATATGATATTGAACGCCTAGCAAGTCGAGTATCTTTCGGAAA
AGCCAACCCTAAAGATCTATTGCAACTCGGACAGACCTTATCACAAATTCCTCGGATTAAAATGATTTTACAGTCCTTCA
ATCAACCTGAGCTTGACATTATTGTCAACAAAATTGACACTATGCCTGAATTAGAAAGTTTAATTAATACGGCGATAGCC
CCAGAAGCACAGGCTACTATCACTGAGGGAAATATTATCAAGTCTGGATTTGATAAGCAATTGGATAATTATCGAACAGT
GATGCGTGAAGGTACAGGTTGGATTGCTGATATTGAAGCTAAGGAAAGAGCAGCAAGTGGTATCGGTACTCTTAAAATTG
ATTATAATAAAAAAGACGGTTATTACTTCCATGTTACCAATTCCAATTTATCACTAGTACCGGAGCATTTTTTCCGTAAA
GCGACATTAAAAAATTCTGAACGCTATGGAACAGCAGAACTAGCCAAAATTGAAGGTGAAATGCTCGAAGCTCGCGAGCA
ATCTTCAAATTTAGAATATGATATTTTTATGCGTGTTCGTGCTCAAGTAGAATCTTATATTAAACGTCTTCAAGAGTTAG
CAAAGACTATTGCAACCGTTGATGTTCTACAGAGTTTGGCAGTAGTTGCAGAAAATCATCACTATGTTCGTCCCAAATTT
AATGATGAACATCAGATTAAGATTAAGAATGGGCGTCATGCAACTGTTGAAAAAGTGATGGGAGTGCAAGAATATATTCC
CAATAGTATCTATTTTGATAGTCAGACAGATATCCAGTTGATTACAGGACCAAATATGAGTGGTAAGTCGACCTATATGC
GCCAGTTAGCTTTGACAGTTATTATGGCACAAATGGGAGGTTTTGTATCGGCAGACGAAGTTGATTTGCCTGTATTTGAT
GCAATATTTACTAGGATTGGTGCTGCTGATGACTTAATTTCTGGGCAATCAACCTTTATGGTAGAAATGATGGAAGCAAA
TCAAGCTGTAAAACGAGCCAGTGATAAATCTTTGATTCTTTTTGATGAATTAGGTCGAGGGACAGCCACTTATGATGGTA
TGGCATTAGCTCAATCGATTATAGAATATATTCATGACCGTGTTAGGGCAAAAACAATGTTTGCAACTCATTACCATGAG
TTGACAGATTTATCTGAACAATTGACAAGGCTTGTCAATGTACACGTGGCTACTTTAGAGAGAGATGGAGAAGTTACCTT
CTTACATAAAATTGAATCTGGACCTGCGGATAAGTCTTATGGGATACATGTCGCAAAAATAGCTGGTTTACCAATTGACT
TATTGGATAGGGCAACTGATGTTTTATCACAGTTGGAAGCTGATGCAGTACAGTTGATCGTATCGCCCTCCCAAGAAGCT
GTTACTGCTGACTTAAATGAGGAACTAGATTCTGAGAAGCAACAAGGACAATTATCGCTTTTTGAAGAACCTTCAAATGC
AGGTAGGGTTATTGAGGAGTTAGAAGCGATAGATATAATGAATCTAACTCCAATGCAAGCTATGAATGCTATATTTGACT
TAAAGAAATTATTATAA

Domains

Predicted by InterProScan.

• MutS domain V (MutS_V) (600-786)

• MutS domain I (MutS_I) (8-118)

• MutS domain III (MutS_III) (257-547)

• MutS family domain IV (MutS_IV) (416-506)

• MutS domain II (MutS_II) (126-240)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	68.998	100	0.69
mutS	Pseudomonas stutzeri strain ATCC 17587	36.519	100	0.374