Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   C2E46_RS02110 Genome accession   NZ_CP026082
Coordinates   373137..373778 (+) Length   213 a.a.
NCBI ID   WP_000357891.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain YZ1605     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 368137..378778
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C2E46_RS02090 (C2E46_02140) - 368581..369318 (+) 738 WP_000406233.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  C2E46_RS02095 (C2E46_02145) pknB 369318..371273 (+) 1956 WP_017643472.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  C2E46_RS02100 (C2E46_02150) liaF 371433..372128 (+) 696 WP_000714456.1 cell wall-active antibiotics response protein LiaF -
  C2E46_RS02105 (C2E46_02155) - 372125..373144 (+) 1020 WP_161501796.1 sensor histidine kinase -
  C2E46_RS02110 (C2E46_02160) vraR 373137..373778 (+) 642 WP_000357891.1 response regulator transcription factor Regulator
  C2E46_RS02115 (C2E46_02165) - 373820..375220 (+) 1401 WP_000339135.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  C2E46_RS02120 (C2E46_02170) - 375222..375578 (+) 357 WP_000689608.1 S1 RNA-binding domain-containing protein -
  C2E46_RS02125 (C2E46_02175) - 375624..376400 (-) 777 WP_000180536.1 glycyl-radical enzyme activating protein -
  C2E46_RS02130 (C2E46_02180) - 376521..377276 (+) 756 WP_001080746.1 DeoR/GlpR family DNA-binding transcription regulator -
  C2E46_RS02135 (C2E46_02185) - 377395..378378 (+) 984 WP_161501974.1 sugar-binding transcriptional regulator -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23634.35 Da        Isoelectric Point: 5.0159

>NTDB_id=224474 C2E46_RS02110 WP_000357891.1 373137..373778(+) (vraR) [Streptococcus agalactiae strain YZ1605]
MDKIKIVLVDDHEMVRLGLKSFLNLQADVEVIGEASNGLEGIKKALELRPDVVVMDLVMPEMDGVEATLALLKDWPEAAI
LVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNAIRKVARGEQAIENEVDKKIKAHDKCPALHEGLTARERDILNLLA
KGYDNQRIADELFISLKTVKTHVSNILGKLNVADRTQAVVYAFQHHLVPQDDE

Nucleotide


Download         Length: 642 bp        

>NTDB_id=224474 C2E46_RS02110 WP_000357891.1 373137..373778(+) (vraR) [Streptococcus agalactiae strain YZ1605]
ATGGATAAAATAAAAATTGTACTTGTTGATGACCATGAGATGGTTCGTCTCGGTTTAAAAAGTTTTTTAAACTTACAAGC
TGATGTTGAAGTAATAGGTGAAGCCTCAAATGGTTTAGAAGGCATAAAAAAAGCCCTGGAGTTACGTCCAGACGTTGTTG
TTATGGATTTAGTAATGCCTGAAATGGATGGTGTAGAAGCAACCTTAGCATTATTGAAGGATTGGCCAGAAGCTGCTATT
TTAGTCTTAACATCTTACTTGGATAATGAAAAAATTTACCCTGTTATTGAAGCAGGTGCCAAAGGCTATATGTTAAAGAC
CTCAAGCGCAGCAGAGATTCTTAATGCCATTCGTAAAGTTGCAAGGGGAGAACAAGCTATTGAAAATGAAGTAGATAAGA
AAATTAAGGCTCATGATAAATGTCCAGCTTTACATGAGGGCTTAACAGCAAGGGAACGTGATATTCTTAATTTATTAGCC
AAAGGTTATGACAATCAAAGGATTGCTGATGAATTATTTATCTCGTTAAAGACTGTTAAAACTCATGTTTCTAATATTTT
GGGAAAACTAAATGTAGCAGATCGAACTCAAGCAGTTGTATATGCTTTCCAACACCATTTGGTACCACAAGATGATGAAT
AA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-118)

Bacterial regulatory proteins, luxR family (GerE)

(148-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.369

96.714

0.526
  degU Bacillus subtilis subsp. subtilis str. 168

37.168

100

0.394

Multiple sequence alignment