Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   A6J87_RS01850 Genome accession   NZ_CP020451
Coordinates   369411..370637 (-) Length   408 a.a.
NCBI ID   WP_002890340.1    Uniprot ID   J7SIE0
Organism   Streptococcus salivarius strain FDAARGOS_259     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 364411..375637
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J87_RS01820 (A6J87_01805) plsY 364759..365400 (+) 642 WP_002886068.1 glycerol-3-phosphate 1-O-acyltransferase PlsY -
  A6J87_RS01825 (A6J87_01810) - 365515..365892 (-) 378 WP_080611483.1 helix-hairpin-helix domain-containing protein -
  A6J87_RS01830 (A6J87_01815) - 365967..366221 (-) 255 WP_002886199.1 DUF1912 family protein -
  A6J87_RS01835 (A6J87_01820) mmuM 366334..367284 (-) 951 WP_080611484.1 homocysteine S-methyltransferase -
  A6J87_RS01840 (A6J87_01825) - 367296..368672 (-) 1377 WP_080611485.1 amino acid permease -
  A6J87_RS01845 (A6J87_01830) yihA 368802..369401 (-) 600 WP_002885996.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  A6J87_RS01850 (A6J87_01835) clpX 369411..370637 (-) 1227 WP_002890340.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  A6J87_RS01855 (A6J87_10760) - 370655..370825 (-) 171 WP_002886174.1 hypothetical protein -
  A6J87_RS01860 (A6J87_01840) - 370830..371333 (-) 504 WP_080611486.1 dihydrofolate reductase -
  A6J87_RS01865 (A6J87_01845) - 371442..372302 (-) 861 WP_002890336.1 thymidylate synthase -
  A6J87_RS01870 (A6J87_01850) - 372775..373941 (+) 1167 WP_080611487.1 hydroxymethylglutaryl-CoA synthase -
  A6J87_RS01875 (A6J87_01855) - 373943..375214 (+) 1272 WP_080611488.1 hydroxymethylglutaryl-CoA reductase, degradative -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 44993.33 Da        Isoelectric Point: 4.3489

>NTDB_id=223223 A6J87_RS01850 WP_002890340.1 369411..370637(-) (clpX) [Streptococcus salivarius strain FDAARGOS_259]
MAGNRNEEMVYCSFCGKNQEEVKKIIAGNGVFICNECVALSQEIIREEMAEEVLADLAETPKPKELLDILNNYVVGQDRA
KRALAVAVYNHYKRINFTESREDNDVDLQKSNILMIGPTGSGKTFLAQTLARSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKN
ILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKAIDDDSSYMQEIVAEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVRIL
TEPRNALVKQYQTLLSYDGVELEFDQDALEAIASKAIERKTGARGLRSIIEEVMMDVMFEIPSQEDVTKVRITKEAVDGT
AAPVLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=223223 A6J87_RS01850 WP_002890340.1 369411..370637(-) (clpX) [Streptococcus salivarius strain FDAARGOS_259]
ATGGCTGGAAATCGTAATGAAGAAATGGTTTATTGTTCATTTTGTGGCAAAAACCAAGAAGAAGTAAAGAAAATTATCGC
TGGGAATGGCGTCTTTATCTGTAACGAATGTGTGGCCTTGTCACAAGAAATCATTCGTGAGGAAATGGCAGAAGAAGTTT
TGGCTGACTTGGCTGAAACTCCAAAGCCAAAAGAACTTTTAGATATTTTGAACAACTATGTCGTGGGGCAGGACCGTGCC
AAACGTGCCTTGGCGGTAGCTGTTTACAATCACTATAAACGTATCAATTTCACAGAAAGTCGTGAAGACAATGATGTGGA
TTTGCAAAAATCAAATATTCTCATGATTGGACCAACTGGTTCAGGGAAGACTTTCTTGGCTCAGACCTTGGCTCGTAGCT
TGAATGTTCCATTTGCGATTGCGGATGCAACATCATTGACAGAGGCAGGTTACGTGGGTGAGGATGTGGAAAATATCCTC
CTCAAACTGATCCAAGCGGCAGACTTCAATATCGAACGTGCGGAACGTGGTATCATCTATGTTGACGAGATTGATAAGAT
TGCTAAAAAGGGTGAAAATGTATCAATCACTCGTGACGTTTCTGGTGAAGGGGTTCAACAAGCTCTCTTGAAGATTATCG
AAGGAACAGTAGCCAGCGTTCCCCCTCAAGGTGGTCGTAAACACCCTAACCAAGAGATGATTCAAATTGATACTAAGAAT
ATTCTCTTTATCGTTGGTGGTGCTTTTGATGGTATCGAAGATATCGTTAAGCAACGTCTTGGTGAGAAAATCATTGGTTT
TGGTCAAAATAATAAGGCAATTGATGATGACTCATCATACATGCAAGAAATTGTGGCTGAAGATATTCAAAAATTCGGTC
TTATCCCTGAGTTTATCGGACGTTTGCCAGTCCTTGCGGCCCTTGAACAGTTAACGGTTGACGACTTGGTTCGTATCTTG
ACAGAGCCTAGAAATGCCTTGGTTAAACAGTACCAAACCCTCTTGTCTTATGATGGGGTTGAACTGGAGTTTGACCAGGA
TGCTCTTGAAGCTATTGCAAGTAAGGCAATTGAACGTAAGACCGGTGCGCGTGGCCTTCGCTCTATCATTGAGGAAGTCA
TGATGGATGTCATGTTTGAAATTCCTAGCCAGGAAGATGTGACTAAGGTTCGTATTACAAAAGAAGCCGTTGACGGCACA
GCTGCTCCAGTTTTGGAAACAGCATAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J7SIE0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

89.976

100

0.902
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.606

98.284

0.566

Multiple sequence alignment