Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   A6J85_RS08960 Genome accession   NZ_CP020450
Coordinates   1791364..1792593 (+) Length   409 a.a.
NCBI ID   WP_008808666.1    Uniprot ID   A0AAP2K4Q6
Organism   Streptococcus gordonii strain FDAARGOS_257     
Function   require for competence development (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1777416..1796651 1791364..1792593 within 0


Gene organization within MGE regions


Location: 1777416..1796651
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J85_RS08875 (A6J85_08780) guaC 1777416..1778399 (+) 984 WP_008808651.1 GMP reductase -
  A6J85_RS08880 (A6J85_08785) - 1778580..1779161 (+) 582 WP_008808652.1 xanthine phosphoribosyltransferase -
  A6J85_RS08885 (A6J85_08790) - 1779163..1780428 (+) 1266 WP_037622361.1 nucleobase:cation symporter-2 family protein -
  A6J85_RS08890 (A6J85_08795) - 1780542..1780724 (-) 183 WP_001117401.1 4-oxalocrotonate tautomerase -
  A6J85_RS08895 (A6J85_08800) - 1780846..1781421 (+) 576 WP_008808654.1 thymidine kinase -
  A6J85_RS08900 (A6J85_08805) prfA 1781454..1782533 (+) 1080 WP_048775986.1 peptide chain release factor 1 -
  A6J85_RS08905 (A6J85_08810) prmC 1782533..1783363 (+) 831 WP_048775984.1 peptide chain release factor N(5)-glutamine methyltransferase -
  A6J85_RS08910 (A6J85_08815) - 1783356..1783946 (+) 591 WP_048775981.1 L-threonylcarbamoyladenylate synthase -
  A6J85_RS08915 (A6J85_08820) glyA 1783994..1785256 (+) 1263 WP_002912430.1 serine hydroxymethyltransferase -
  A6J85_RS08920 (A6J85_08825) - 1785258..1786232 (+) 975 WP_061601988.1 nucleoid-associated protein -
  A6J85_RS08925 (A6J85_08830) - 1786232..1786834 (+) 603 WP_082307639.1 lysozyme family protein -
  A6J85_RS08930 (A6J85_08835) - 1786948..1787793 (+) 846 WP_060970606.1 alpha/beta hydrolase -
  A6J85_RS08935 (A6J85_08840) - 1787969..1788928 (+) 960 WP_045774034.1 ROK family glucokinase -
  A6J85_RS08940 (A6J85_08845) - 1789027..1789866 (+) 840 WP_045634818.1 thymidylate synthase -
  A6J85_RS08945 (A6J85_08850) - 1789997..1790497 (+) 501 WP_045634819.1 hypothetical protein -
  A6J85_RS08950 (A6J85_08855) - 1790643..1791155 (+) 513 WP_045634820.1 dihydrofolate reductase -
  A6J85_RS08960 (A6J85_08860) clpX 1791364..1792593 (+) 1230 WP_008808666.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  A6J85_RS08965 (A6J85_08865) yihA 1792602..1793195 (+) 594 WP_045634822.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  A6J85_RS08970 (A6J85_08870) - 1793329..1794018 (+) 690 WP_012000547.1 glucosaminidase domain-containing protein -
  A6J85_RS08975 (A6J85_08875) - 1794146..1794943 (+) 798 WP_060954898.1 formate/nitrite transporter family protein -
  A6J85_RS08980 (A6J85_08880) - 1795037..1795861 (+) 825 WP_060553604.1 alpha/beta hydrolase -
  A6J85_RS08985 (A6J85_08885) - 1795911..1796651 (+) 741 WP_082307796.1 esterase family protein -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 45650.21 Da        Isoelectric Point: 4.4870

>NTDB_id=223206 A6J85_RS08960 WP_008808666.1 1791364..1792593(+) (clpX) [Streptococcus gordonii strain FDAARGOS_257]
MPTNRNEEMMVYCSFCGKNQDEVQKIIAGNNAFICNECVELAQEIIREELAEEVLADLSEVPKPQELLHILNHYVIGQER
AKRALAVAVYNHYKRINFHDSREEDDVELQKSNILMIGPTGSGKTFLAQTLARSLNVPFAIADATALTEAGYVGEDVENI
LLKLLQAADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDTK
NILFIVGGAFDGIEEIVKQRLGEKIIGFGQNNKAIDENESYMQAIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRI
LREPKNALVKQYQALLSYDDVKLEFDDDALQEIANKAIERKTGARGLRSIIEETMMDVMFEVPSKENVKLVRITKEAVDG
TDKPILETA

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=223206 A6J85_RS08960 WP_008808666.1 1791364..1792593(+) (clpX) [Streptococcus gordonii strain FDAARGOS_257]
ATGCCTACAAATCGTAATGAAGAGATGATGGTATATTGTTCATTTTGTGGGAAGAACCAAGATGAGGTTCAAAAGATTAT
TGCGGGTAATAACGCTTTTATTTGTAATGAGTGTGTAGAATTAGCACAAGAAATTATCCGTGAAGAATTAGCCGAAGAAG
TCTTAGCTGACTTGTCAGAGGTTCCAAAACCTCAAGAATTATTGCATATTCTAAACCATTATGTCATCGGTCAAGAGCGC
GCTAAAAGAGCGCTAGCTGTAGCAGTATATAATCACTACAAGCGCATTAATTTTCACGACAGCCGTGAAGAAGATGATGT
TGAATTGCAAAAATCAAATATCTTAATGATCGGTCCAACGGGTTCTGGAAAAACTTTTCTTGCTCAGACCTTGGCTAGAA
GTTTAAATGTACCGTTTGCGATTGCTGATGCGACAGCTTTAACAGAGGCTGGTTATGTCGGAGAAGATGTAGAAAATATT
CTTTTAAAACTTTTGCAGGCGGCTGATTTCAATATCGAACGTGCAGAACGCGGAATCATATACGTAGATGAGATTGATAA
GATCGCTAAAAAGAGTGAAAATGTTTCTATCACGCGCGATGTATCAGGTGAAGGAGTACAGCAGGCTCTCTTAAAAATTA
TTGAGGGTACTGTAGCAAGTGTTCCGCCTCAAGGAGGTCGCAAACATCCGCAGCAAGAGATGATTCAGGTTGATACCAAA
AATATTCTTTTCATCGTTGGTGGTGCCTTTGATGGGATTGAAGAAATTGTAAAACAACGTTTGGGCGAGAAAATTATTGG
TTTTGGTCAAAATAACAAAGCTATCGATGAAAACGAGTCCTACATGCAAGCTATTATTGCTGAAGATATTCAAAAATTTG
GAATTATCCCTGAATTAATTGGTCGTTTGCCTGTTTTTGCTGCTCTGGAACAACTGACTGTAGACGACTTGGTTCGTATT
CTTCGCGAGCCTAAGAATGCTTTGGTTAAACAATACCAGGCTCTCTTGTCTTACGATGATGTTAAACTAGAGTTTGATGA
TGATGCTTTACAGGAAATCGCGAACAAGGCCATTGAGCGCAAAACTGGGGCCCGTGGTCTACGTTCTATCATCGAAGAAA
CAATGATGGATGTTATGTTTGAAGTTCCAAGTAAAGAAAATGTGAAACTTGTCCGAATCACTAAGGAAGCTGTTGATGGT
ACTGATAAGCCAATTTTAGAGACTGCTTGA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(110-305)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(312-389)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

85.575

100

0.856
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.105

98.044

0.57

Multiple sequence alignment