Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   A6J85_RS01265 Genome accession   NZ_CP020450
Coordinates   241977..242666 (-) Length   229 a.a.
NCBI ID   WP_082307158.1    Uniprot ID   -
Organism   Streptococcus gordonii strain FDAARGOS_257     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 236977..247666
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J85_RS01245 (A6J85_01240) nrdR 237378..237851 (-) 474 WP_008808512.1 transcriptional regulator NrdR -
  A6J85_RS01250 (A6J85_01245) - 238031..238447 (+) 417 WP_061601489.1 hypothetical protein -
  A6J85_RS01255 (A6J85_01250) - 238590..239405 (-) 816 WP_061601490.1 endonuclease/exonuclease/phosphatase family protein -
  A6J85_RS01260 (A6J85_01255) - 239423..241615 (-) 2193 WP_061601491.1 PTS transporter subunit IIBC -
  A6J85_RS01265 (A6J85_01260) covR 241977..242666 (-) 690 WP_082307158.1 response regulator transcription factor Regulator
  A6J85_RS01270 (A6J85_01265) gndA 242679..244103 (-) 1425 WP_061601492.1 NADP-dependent phosphogluconate dehydrogenase -
  A6J85_RS01275 (A6J85_01270) - 244239..245720 (-) 1482 WP_061601493.1 flotillin family protein -
  A6J85_RS01280 (A6J85_01275) - 245823..246353 (-) 531 WP_045505786.1 DUF177 domain-containing protein -
  A6J85_RS01285 (A6J85_01280) - 246451..247320 (+) 870 WP_061601494.1 Rgg/GadR/MutR family transcriptional regulator -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26289.34 Da        Isoelectric Point: 5.4778

>NTDB_id=223154 A6J85_RS01265 WP_082307158.1 241977..242666(-) (covR) [Streptococcus gordonii strain FDAARGOS_257]
MAKRILLVENEKNLARFIMLELQKESYQVDLAETGQEGLALAKENDYDLLLLNNQFADGTAFAFAQQLSLLKPAAVIIVM
VSREEIADSAEEIQQFAVSYMVKPFIISDLVDKISAIFRGRDFIDQKCSRLKVPTAYRNLRVDLKNHTVYRGEEIIALTR
REYDLLVTLMSSNKVMSREQLLDRVWKYESASETNIVDVYIRYLRSKIDLPGQESYIKTVRGIGYSMQG

Nucleotide


Download         Length: 690 bp        

>NTDB_id=223154 A6J85_RS01265 WP_082307158.1 241977..242666(-) (covR) [Streptococcus gordonii strain FDAARGOS_257]
ATGGCGAAGCGGATTTTATTAGTTGAAAATGAAAAGAATCTAGCACGATTTATCATGCTGGAATTACAAAAGGAAAGTTA
TCAAGTAGACCTAGCGGAAACAGGGCAAGAGGGACTAGCTCTAGCAAAGGAAAACGATTATGATTTACTTTTACTAAATA
ATCAGTTTGCTGATGGAACAGCCTTTGCCTTTGCTCAACAATTAAGTTTATTAAAACCAGCTGCAGTAATCATTGTAATG
GTGAGCCGAGAGGAGATTGCGGATTCGGCTGAAGAGATTCAGCAGTTTGCAGTTTCTTATATGGTAAAACCCTTTATTAT
TAGTGATCTGGTTGATAAAATATCTGCTATTTTTCGTGGACGAGATTTTATTGATCAGAAATGTAGCCGGTTAAAAGTTC
CTACTGCTTATCGAAATCTGCGGGTTGATTTGAAAAATCATACGGTTTATCGAGGGGAAGAAATTATTGCTTTGACGAGA
CGAGAGTATGATTTACTAGTGACTCTAATGAGCAGTAATAAGGTGATGAGCCGTGAGCAACTGTTAGATCGAGTGTGGAA
GTATGAAAGTGCATCTGAGACTAATATAGTGGATGTATATATTCGTTACCTCCGTAGTAAAATCGATCTTCCAGGACAAG
AAAGTTATATTAAAACCGTTCGTGGAATTGGTTATTCCATGCAGGGGTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

51.77

98.69

0.511
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.614

99.563

0.454

Multiple sequence alignment