Detailed information NTG0223045

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: A6J74_RS11035
• Genome accession: NZ_CP020437
• Coordinates: 1806100..1808700 (-)
• Length: 866 a.a.
• NCBI ID: WP_000365397.1
• Uniprot ID: A0A2B6H9B6
• Organism: Bacillus sp. FDAARGOS_235
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1801100..1813700

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6J74_RS11005 (A6J74_11015)	fabF	1801401..1802639 (-)	1239	WP_000412641.1	beta-ketoacyl-ACP synthase II	-
A6J74_RS11010 (A6J74_11020)	fabH	1802670..1803602 (-)	933	WP_001100553.1	beta-ketoacyl-ACP synthase III	-
A6J74_RS11015 (A6J74_11025)	comZ	1803847..1804023 (-)	177	WP_001003338.1	ComZ family protein	Regulator
A6J74_RS11020 (A6J74_11030)	-	1804088..1804960 (-)	873	WP_000486174.1	NAD(P)-dependent oxidoreductase	-
A6J74_RS11025 (A6J74_11035)	-	1804990..1805724 (-)	735	WP_000028709.1	hypothetical protein	-
A6J74_RS11030 (A6J74_11040)	-	1805881..1806063 (+)	183	WP_001211112.1	YjzD family protein	-
A6J74_RS11035 (A6J74_11045)	clpC	1806100..1808700 (-)	2601	WP_000365397.1	ATP-dependent chaperone ClpB	Regulator
A6J74_RS11040 (A6J74_11050)	-	1808911..1809090 (-)	180	WP_002093816.1	YjzC family protein	-
A6J74_RS11050 (A6J74_11060)	-	1809583..1810392 (+)	810	WP_000043171.1	Cof-type HAD-IIB family hydrolase	-
A6J74_RS11055 (A6J74_11065)	-	1810497..1810637 (+)	141	WP_000516816.1	hypothetical protein	-
A6J74_RS11060 (A6J74_11070)	-	1810638..1810835 (+)	198	WP_000527396.1	DUF3813 domain-containing protein	-
A6J74_RS11065 (A6J74_11075)	-	1810861..1811718 (-)	858	WP_000364440.1	YitT family protein	-
A6J74_RS11070 (A6J74_11080)	-	1811819..1811950 (+)	132	WP_001120851.1	DUF3941 domain-containing protein	-
A6J74_RS11075 (A6J74_11085)	prsA	1812080..1812937 (+)	858	WP_001214219.1	peptidylprolyl isomerase PrsA	-
A6J74_RS11080 (A6J74_11090)	-	1813006..1813591 (-)	586	Protein_1847	hypothetical protein	-

Sequence

Protein

• Length: 866 a.a.
• Molecular weight: 97611.62 Da
• Isoelectric Point: 5.1950

>NTDB_id=223045 A6J74_RS11035 WP_000365397.1 1806100..1808700(-) (clpC) [Bacillus sp. FDAARGOS_235]
MDLNQMTTKTQEAIMSAQSLAVSHHHQEVDTVHLLLALLEEQDGLAVRIFQKMNVDIEALKQDVENVIKKKPSVTGSGAE
VGKLYITSNLQQLLVRAGKEAEKLQDDYISVEHVLLAFSEEKGDINHLFTRLHITKDNLLQSLMTVRGNQRVTSQNPEAT
YEALEKYGRDLVAEVRAGKIDPVIGRDSEIRRVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPEGLKDRTI
FALDMSALVAGAKFRGEFEERLQAVLNEIKKSEGRILLFIDELHTIVGAGKTEGAMDAGNMLKPMLARGELHCIGATTLD
EYRKYIEKDPALERRFQQVLAEEPTVEDTISILRGLKERFEIYHGVNIHDRAIVAASVLSDRYISDRFLPDKAIDLVDEA
CATIRTEIDSMPTELDEVTRRIMQLEIEEAALGKEKDFGSQERLKTLQRELSDLKEVASSMRAKWEKEKEDIHKVRDLRE
HLERLRRELEEAEGNYDLNKAAELRHGKIPAIEKELKEAEEMSAHNKQENRLLREEVSEEEIADIVSRWTGIPVAKLVEG
EREKLLRLEQILSERVIGQEEAVSLVSDAVLRARAGIKDPNRPIGSFIFLGPTGVGKTELAKTLAQSLFDSEEQMIRIDM
SEYMEKHAVSRLIGAPPGYVGYEEGGQLTEAVRRKPYSVILLDEIEKAHPEVFNILLQMLDDGRITDSQGRTVDFKNTVI
IMTSNIGSAHLLDGLEADGSIKEESRELVMGQLRGHFRPEFLNRVDEIILFKPLTTNEIKGIVDKIVKELQGRLADRHIT
VELTDSAKEFVVEAGFDPMYGARPLKRYVQRQVETKLARELIAGTITDNSHVVVDVENNELVVHVK

Nucleotide

• Length: 2601 bp

>NTDB_id=223045 A6J74_RS11035 WP_000365397.1 1806100..1808700(-) (clpC) [Bacillus sp. FDAARGOS_235]
ATGGACTTAAATCAAATGACAACGAAAACACAAGAGGCGATTATGAGTGCCCAATCTTTAGCGGTATCTCATCATCACCA
AGAGGTGGATACTGTTCATCTATTACTTGCATTATTAGAGGAGCAAGATGGATTAGCAGTACGTATATTTCAAAAAATGA
ATGTTGATATAGAAGCATTGAAGCAAGATGTAGAAAATGTAATTAAAAAGAAACCTTCTGTAACGGGAAGCGGAGCAGAA
GTTGGGAAATTGTATATAACAAGCAATCTGCAGCAACTGCTTGTAAGAGCAGGGAAAGAAGCAGAAAAACTGCAGGATGA
TTACATTTCAGTAGAACATGTATTGCTTGCTTTTTCTGAAGAAAAAGGCGATATCAATCATTTATTTACAAGATTGCATA
TTACGAAAGATAACTTATTACAGTCTTTAATGACAGTTCGGGGGAATCAAAGAGTGACTAGTCAAAATCCAGAAGCAACT
TATGAAGCGTTAGAAAAATATGGCCGTGATTTAGTGGCGGAAGTGAGAGCAGGGAAAATTGATCCTGTTATCGGACGAGA
TAGTGAAATTCGCCGCGTTATTCGCATTCTTTCACGTAAAACGAAAAACAACCCTGTTTTAATTGGTGAGCCAGGTGTTG
GTAAAACAGCAATTGTTGAAGGATTAGCACAGCGTATCGTGAAAAAAGATGTACCAGAAGGGTTAAAAGATAGAACAATC
TTTGCATTAGATATGAGTGCACTTGTAGCCGGAGCAAAATTCCGTGGTGAATTTGAAGAGCGCCTGCAAGCTGTATTAAA
TGAAATTAAAAAGAGTGAAGGCCGTATTTTATTATTCATTGATGAACTTCATACAATCGTCGGTGCTGGTAAAACAGAAG
GTGCGATGGACGCAGGGAATATGTTAAAACCGATGCTTGCTCGTGGTGAACTGCATTGTATCGGGGCAACGACATTAGAT
GAATATCGTAAATATATTGAGAAAGACCCAGCGTTAGAAAGACGTTTCCAACAAGTATTAGCAGAGGAACCGACTGTTGA
AGATACAATCTCCATTTTACGTGGTTTAAAAGAGCGTTTTGAAATTTATCACGGTGTAAATATTCATGACCGCGCGATTG
TAGCAGCATCTGTTTTATCAGATCGATATATTTCAGATCGCTTCTTACCGGATAAAGCAATTGACCTTGTTGACGAAGCG
TGCGCAACAATTCGTACAGAAATTGATTCTATGCCAACAGAATTAGATGAAGTAACGCGCCGTATTATGCAGCTGGAAAT
TGAAGAAGCCGCTCTTGGAAAAGAGAAGGACTTTGGTAGCCAAGAACGTCTGAAAACATTGCAACGTGAATTATCGGATT
TAAAAGAAGTTGCAAGTAGCATGAGAGCGAAATGGGAGAAAGAAAAAGAAGATATTCACAAAGTTCGTGACTTACGTGAA
CATTTAGAGCGTCTGCGCCGTGAATTAGAAGAAGCAGAAGGTAATTACGATTTAAATAAAGCAGCTGAACTTCGTCACGG
AAAAATTCCTGCAATTGAAAAAGAATTAAAAGAAGCGGAAGAAATGAGCGCACATAATAAACAAGAAAATCGTTTATTAC
GCGAGGAAGTCAGTGAAGAAGAAATTGCTGATATCGTTTCACGCTGGACTGGTATTCCTGTCGCAAAACTCGTTGAGGGT
GAACGTGAGAAATTACTACGCTTAGAGCAAATTTTATCAGAGCGTGTCATCGGACAAGAGGAAGCGGTAAGTTTAGTATC
AGACGCAGTTCTTCGTGCACGCGCTGGTATTAAAGACCCGAACCGTCCAATTGGTTCCTTCATTTTCTTAGGACCGACAG
GTGTTGGTAAAACAGAACTTGCAAAAACGTTAGCGCAGTCTTTATTCGATAGTGAAGAGCAAATGATTCGCATCGACATG
TCTGAGTACATGGAGAAACATGCTGTGTCACGCTTAATTGGTGCACCTCCTGGATATGTTGGATATGAAGAGGGCGGTCA
ATTAACGGAAGCAGTAAGACGTAAACCGTATTCCGTTATTTTGTTAGACGAAATCGAAAAAGCGCATCCAGAAGTATTCA
ACATTTTATTACAAATGTTAGATGATGGACGCATTACAGATTCGCAAGGACGTACAGTAGACTTTAAAAACACGGTTATT
ATTATGACTTCAAATATTGGATCTGCTCATTTATTAGATGGATTAGAAGCAGATGGTTCCATTAAAGAGGAATCAAGAGA
ACTTGTCATGGGACAATTAAGAGGACATTTCCGACCAGAGTTTTTAAATCGTGTCGATGAAATTATTTTATTCAAGCCTC
TTACAACGAATGAAATTAAAGGTATTGTTGATAAAATTGTAAAAGAATTACAAGGTCGTTTAGCTGACCGTCATATTACG
GTAGAATTAACGGATTCTGCAAAAGAATTTGTTGTAGAAGCTGGCTTTGATCCGATGTACGGAGCTCGTCCATTAAAACG
ATACGTACAGCGTCAAGTGGAAACGAAATTAGCGAGAGAATTAATTGCAGGCACAATTACGGATAATAGTCACGTAGTTG
TTGATGTAGAAAATAACGAATTAGTTGTTCATGTGAAATGA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (602-768)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (774-854)

• AAA lid domain (AAA_lid_9) (345-447)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (97-148)

• ATPase family associated with various cellular activities (AAA) (AAA) (206-339)

3D structure

• AlphaFold DB: A0A2B6H9B6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	47.657	100	0.482
clpC	Lactococcus lactis subsp. cremoris KW2	46.704	82.333	0.385