Detailed information NTG0222969

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: C2I05_RS11530
• Genome accession: NZ_CP026039
• Coordinates: 2158877..2159959 (+)
• Length: 360 a.a.
• NCBI ID: WP_003225736.1
• Uniprot ID: P37573
• Organism: Bacillus subtilis strain PK1_2
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 2153877..2164959

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C2I05_RS11515 (C2I05_11490)	mcsB	2153885..2154976 (+)	1092	WP_003235007.1	protein arginine kinase	-
C2I05_RS11520 (C2I05_11495)	clpC	2154973..2157405 (+)	2433	WP_049140374.1	ATP-dependent protease ATP-binding subunit ClpC	Regulator
C2I05_RS11525 (C2I05_11500)	radA/sms	2157497..2158873 (+)	1377	WP_015252992.1	DNA repair protein RadA	Machinery gene
C2I05_RS11530 (C2I05_11505)	disA	2158877..2159959 (+)	1083	WP_003225736.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
C2I05_RS11535 (C2I05_11510)	yacL	2160075..2161175 (+)	1101	WP_003235014.1	PIN/TRAM domain-containing protein	-
C2I05_RS11540 (C2I05_11515)	ispD	2161190..2161888 (+)	699	WP_003235019.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
C2I05_RS11545 (C2I05_11520)	ispF	2161881..2162357 (+)	477	WP_014475594.1	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	-
C2I05_RS11550 (C2I05_11525)	gltX	2162448..2163899 (+)	1452	WP_014478617.1	glutamate--tRNA ligase	-
C2I05_RS11555 (C2I05_11535)	cysE	2164201..2164854 (+)	654	WP_003225749.1	serine O-acetyltransferase	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 40734.29 Da
• Isoelectric Point: 5.7343

>NTDB_id=222969 C2I05_RS11530 WP_003225736.1 2158877..2159959(+) (disA) [Bacillus subtilis strain PK1_2]
MEKEKKGAKHELDLSSILQFVAPGTPLRAGMENVLRANTGGLIVVGYNDKVKEVVDGGFHINTAFSPAHLYELAKMDGAI
ILSDSGQKILYANTQLMPDATISSSETGMRHRTAERVAKQTGCLVIAISERRNVITLYQENMKYTLKDIGFILTKANQAI
QTLEKYKTILDKTINALNALEFEELVTFSDVLSVMHRYEMVLRIKNEINMYIKELGTEGHLIKLQVIELITDMEEEAALF
IKDYVKEKIKDPFVLLKELQDMSSYDLLDDSIVYKLLGYPASTNLDDYVLPRGYRLLNKIPRLPMPIVENVVEAFGVLPR
IIEASAEELDEVEGIGEVRAQKIKKGLKRLQEKHYLDRQL

Nucleotide

• Length: 1083 bp

>NTDB_id=222969 C2I05_RS11530 WP_003225736.1 2158877..2159959(+) (disA) [Bacillus subtilis strain PK1_2]
ATGGAAAAAGAGAAAAAAGGGGCGAAACACGAGTTAGACCTGTCATCTATATTGCAGTTTGTTGCTCCGGGTACACCGCT
CAGAGCGGGGATGGAAAACGTCTTGAGAGCAAATACAGGCGGTCTGATTGTTGTTGGATATAATGATAAAGTAAAAGAAG
TGGTGGACGGCGGCTTTCACATAAACACGGCTTTTTCTCCGGCGCATTTATATGAGTTGGCTAAAATGGATGGAGCGATC
ATTTTAAGTGATTCGGGTCAAAAGATCCTCTACGCGAATACTCAGCTGATGCCGGATGCCACAATTTCTTCATCAGAAAC
AGGAATGCGGCACAGAACTGCCGAAAGAGTAGCTAAGCAAACTGGCTGTCTTGTAATCGCTATTTCTGAAAGAAGAAATG
TCATAACGTTATATCAGGAAAACATGAAGTATACACTAAAAGACATAGGATTTATTTTAACCAAGGCGAACCAAGCCATT
CAAACACTTGAAAAGTATAAGACAATCCTCGATAAAACGATTAATGCACTGAACGCGTTAGAGTTTGAGGAACTTGTTAC
CTTCAGTGATGTCTTGTCTGTCATGCATCGTTATGAAATGGTACTGAGAATCAAAAACGAAATTAATATGTATATCAAAG
AGCTGGGGACAGAAGGGCATCTGATCAAACTGCAAGTCATTGAATTGATTACGGATATGGAAGAAGAGGCCGCTTTATTT
ATTAAGGACTATGTAAAAGAAAAGATTAAAGATCCGTTTGTTCTCTTGAAGGAGCTGCAGGATATGTCCAGTTATGATCT
GCTGGATGATTCCATTGTGTATAAGCTTCTCGGTTACCCTGCTTCTACTAATCTTGATGATTATGTATTGCCGAGAGGAT
ACAGGCTGTTAAATAAGATACCGCGTCTTCCGATGCCGATTGTTGAAAATGTTGTAGAAGCATTTGGAGTCCTACCAAGG
ATTATTGAGGCGAGTGCAGAAGAATTAGATGAAGTAGAGGGAATCGGTGAAGTACGAGCCCAAAAAATCAAAAAAGGATT
AAAACGCCTGCAAGAGAAGCATTATTTAGACAGACAACTGTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (29-141)

• DisA bacterial checkpoint controller linker region (DisA-linker) (146-284)

3D structure

• AlphaFold DB: P37573

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	100	100	1