Detailed information NTG0222968

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: A6J68_RS10720
• Genome accession: NZ_CP020432
• Coordinates: 2046722..2049169 (-)
• Length: 815 a.a.
• NCBI ID: WP_000020286.1
• Uniprot ID: -
• Organism: Streptococcus sp. 'group B' strain FDAARGOS_229
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 2041722..2054169

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6J68_RS10695 (A6J68_10585)	-	2042003..2043259 (+)	1257	WP_001285395.1	toxic anion resistance protein	-
A6J68_RS10700 (A6J68_10590)	hslO	2043399..2044274 (+)	876	WP_000357828.1	Hsp33 family molecular chaperone HslO	-
A6J68_RS10705 (A6J68_10595)	dusB	2044258..2045235 (+)	978	WP_000192729.1	tRNA dihydrouridine synthase DusB	-
A6J68_RS10710 (A6J68_10600)	-	2045356..2045997 (+)	642	WP_000909520.1	deoxynucleoside kinase	-
A6J68_RS10715 (A6J68_10605)	-	2046011..2046502 (+)	492	WP_000586900.1	GNAT family N-acetyltransferase	-
A6J68_RS10720 (A6J68_10610)	clpC	2046722..2049169 (-)	2448	WP_000020286.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
A6J68_RS10725 (A6J68_10615)	-	2049166..2049630 (-)	465	WP_000985641.1	CtsR family transcriptional regulator	-
A6J68_RS10730 (A6J68_10620)	-	2049803..2050264 (+)	462	WP_001106578.1	COG2426 family protein	-
A6J68_RS10735 (A6J68_10625)	tsf	2050423..2051463 (-)	1041	WP_000808080.1	translation elongation factor Ts	-
A6J68_RS10740 (A6J68_10630)	rpsB	2051557..2052327 (-)	771	WP_000268454.1	30S ribosomal protein S2	-
A6J68_RS10745 (A6J68_10635)	ahpC	2052604..2053164 (+)	561	WP_000060538.1	alkyl hydroperoxide reductase subunit C	-

Sequence

Protein

• Length: 815 a.a.
• Molecular weight: 90627.16 Da
• Isoelectric Point: 6.0379

>NTDB_id=222968 A6J68_RS10720 WP_000020286.1 2046722..2049169(-) (clpC) [Streptococcus sp. 'group B' strain FDAARGOS_229]
MSHYSIKLQEVFRLAQFQAARYESHYLESWHLLLAMVLVHDSVAGLTFAEYESEVAIEEYEAATILALGRAPKEEITNYQ
FLEQSPALKKILKLAENISIVVGAEDVGTEHVLLAMLVNKDLLATRILELVGFRGQDDGESVRMVDLRKALERHAGFTKD
DIKAIYELRNPKKAKSGASFSDMMKPPSTAGDLADFTRDLSQMAVDGEIEPVIGRDKEISRMVQVLSRKTKNNPVLVGDA
GVGKTALAYGLAQRIANGNIPYELRDMRVLELDMMSVVAGTRFRGDFEERMNQIIADIEEDGHIILFIDELHTIMGSGSG
IDSTLDAANILKPALARGTLRTIGATTQEEYQKHIEKDAALSRRFAKVLVEEPNLEDAYEILLGLKPAYEAFHNVTISDE
AVMTAVKVAHRYLTSKNLPDSAIDLLDEASATVQMMIKKNAPSLLTEVDQAILDDDMKSASKALKASHKDKKHKPIAVTE
DHIMATLSRLSGIPVEKLTQADSKKYLNLEKELHKRVIGQDDAVTAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKTE
LAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQV
LDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDISHDYTAMQKRIMEELKKAYRPEFINRIDEKVVFHS
LSQDNMREVVKIMVKPLILALKDKGMDLKFQPSALKHLAEDGYDIEMGARPLRRTIQTQVEDHLSELLLANQVKEGQVIK
IGVSKGKLKFDIAKS

Nucleotide

• Length: 2448 bp

>NTDB_id=222968 A6J68_RS10720 WP_000020286.1 2046722..2049169(-) (clpC) [Streptococcus sp. 'group B' strain FDAARGOS_229]
ATGAGTCATTATTCCATAAAATTACAAGAAGTATTCAGATTGGCGCAATTTCAAGCAGCACGCTATGAAAGTCACTATTT
AGAAAGCTGGCATCTTCTTTTAGCAATGGTTTTAGTTCATGATTCAGTAGCTGGTTTGACATTTGCTGAATATGAGTCTG
AAGTTGCAATTGAAGAGTACGAAGCAGCAACAATTTTAGCTTTAGGTAGAGCACCGAAAGAAGAGATTACCAATTATCAA
TTTTTAGAGCAATCACCAGCTTTGAAAAAGATCTTAAAGTTAGCAGAAAATATTAGTATCGTAGTAGGAGCTGAAGATGT
GGGTACTGAACATGTCTTGCTTGCTATGTTGGTTAATAAAGATTTATTAGCCACACGTATCTTAGAATTAGTTGGCTTTA
GAGGTCAAGACGATGGTGAATCAGTTCGTATGGTTGATTTACGTAAGGCTCTAGAACGTCATGCCGGTTTTACAAAAGAT
GATATCAAAGCAATTTATGAATTACGTAATCCTAAAAAAGCAAAGTCGGGTGCTTCTTTTTCTGATATGATGAAACCACC
AAGTACTGCTGGTGATTTAGCTGATTTCACACGTGATTTATCACAGATGGCGGTTGATGGGGAAATTGAACCTGTTATTG
GGCGTGATAAAGAAATTTCACGTATGGTCCAAGTCTTAAGTCGTAAAACAAAGAATAATCCTGTCTTAGTTGGAGATGCG
GGTGTCGGTAAAACAGCTTTGGCGTACGGTCTAGCACAACGTATTGCTAATGGAAATATTCCTTATGAGCTTAGAGATAT
GCGTGTTCTAGAGTTAGATATGATGAGCGTTGTTGCTGGAACTCGTTTTCGTGGTGATTTTGAGGAACGTATGAATCAAA
TCATTGCAGATATTGAAGAAGACGGTCATATTATTCTTTTCATTGATGAACTGCATACTATTATGGGTTCTGGCTCTGGT
ATTGATAGCACACTTGATGCTGCTAATATTTTAAAACCAGCTTTGGCTCGAGGCACTTTACGCACTATTGGAGCAACAAC
TCAAGAGGAATATCAAAAGCATATTGAAAAAGATGCTGCTTTATCTCGTCGCTTTGCAAAAGTTTTAGTAGAAGAACCAA
ATCTTGAAGACGCATATGAAATTCTACTTGGATTGAAGCCAGCGTATGAAGCCTTTCATAATGTTACCATTTCAGATGAA
GCAGTTATGACTGCTGTAAAAGTGGCTCATCGTTATTTGACAAGTAAGAATTTACCAGACTCAGCTATAGACTTACTTGA
TGAAGCTTCTGCCACTGTGCAAATGATGATTAAGAAAAATGCTCCATCGCTTTTAACAGAAGTTGACCAAGCTATTTTAG
ATGATGATATGAAATCTGCTTCTAAAGCTCTAAAAGCAAGTCATAAGGATAAAAAGCATAAGCCTATTGCCGTAACCGAA
GATCATATTATGGCAACTCTCAGCCGTCTATCTGGTATTCCTGTTGAAAAATTGACACAAGCTGATAGTAAAAAATACCT
CAATTTAGAAAAAGAATTGCATAAACGTGTTATCGGTCAAGATGATGCAGTTACTGCCATTAGTCGTGCTATCCGTCGCA
ATCAATCTGGCATTCGTACTGGTAAGCGTCCTATTGGTTCCTTTATGTTCTTGGGACCAACTGGTGTTGGTAAGACAGAG
TTAGCAAAAGCCTTGGCAGAAGTGTTGTTTGATGATGAATCAGCCCTAATTCGTTTTGATATGTCGGAATATATGGAAAA
ATTCGCAGCTTCTCGCCTGAATGGGGCACCTCCAGGTTATGTTGGTTATGATGAAGGAGGAGAGCTGACTGAAAAAGTAC
GCAATAAACCATATTCAGTTTTACTTTTTGATGAAGTTGAAAAAGCTCATCCAGATATTTTTAATGTATTATTACAAGTG
CTTGATGATGGCGTTTTAACAGATAGTCGAGGACGAAAAGTTGACTTTTCAAATACTATAATCATTATGACTTCTAATTT
AGGAGCAACTGCATTACGTGACGATAAAACAGTTGGTTTTGGAGCTAAGGATATCAGCCATGATTATACTGCTATGCAAA
AACGTATTATGGAGGAGCTTAAAAAAGCTTATCGACCAGAGTTTATCAATCGTATTGATGAGAAAGTTGTATTCCATAGT
CTCAGTCAAGATAATATGCGTGAAGTTGTGAAAATTATGGTTAAACCTTTAATTTTAGCGCTTAAAGATAAAGGTATGGA
TCTGAAATTCCAGCCTTCAGCCTTGAAACACTTGGCAGAGGATGGCTATGATATAGAAATGGGTGCTCGTCCACTGCGTA
GAACTATTCAAACGCAAGTAGAGGATCATTTATCAGAACTACTATTGGCAAATCAAGTGAAAGAGGGGCAAGTAATTAAG
ATTGGCGTATCCAAAGGCAAATTGAAATTTGATATTGCAAAATCATAA

Domains

Predicted by InterproScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (105-132)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-46)

• AAA lid domain (AAA_lid_9) (375-471)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (721-801)

• ATPase family associated with various cellular activities (AAA) (AAA) (235-367)

• AAA domain (Cdc48 subfamily) (AAA_2) (543-714)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	76.601	99.632	0.763
clpC	Streptococcus thermophilus LMG 18311	72.761	100	0.728
clpC	Streptococcus thermophilus LMD-9	72.638	100	0.726
clpC	Streptococcus pneumoniae Rx1	68.55	99.877	0.685
clpC	Streptococcus pneumoniae D39	68.55	99.877	0.685
clpC	Streptococcus pneumoniae TIGR4	68.55	99.877	0.685
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.434	100	0.493
clpC	Bacillus subtilis subsp. subtilis str. 168	45.683	100	0.467
clpE	Streptococcus mutans UA159	46.238	78.282	0.362