Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   C2I05_RS06780 Genome accession   NZ_CP026039
Coordinates   1231726..1232361 (-) Length   211 a.a.
NCBI ID   WP_021480575.1    Uniprot ID   -
Organism   Bacillus subtilis strain PK1_2     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1226726..1237361
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C2I05_RS06760 (C2I05_06730) yvzF 1227783..1227968 (-) 186 WP_003244599.1 YvzF family protein -
  C2I05_RS06765 (C2I05_06735) gerAA 1228086..1229534 (+) 1449 WP_014477941.1 spore germination receptor protein GerAA -
  C2I05_RS06770 (C2I05_06740) gerAB 1229503..1230600 (+) 1098 WP_021480573.1 spore germination receptor protein GerAB -
  C2I05_RS06775 (C2I05_06745) gerAC 1230597..1231718 (+) 1122 WP_021480574.1 spore germination receptor protein GerAC -
  C2I05_RS06780 (C2I05_06750) vraR 1231726..1232361 (-) 636 WP_021480575.1 two-component system response regulator LiaR Regulator
  C2I05_RS06785 (C2I05_06755) liaS 1232339..1233421 (-) 1083 WP_249847996.1 two-component system sensor histidine kinase LiaS -
  C2I05_RS06790 (C2I05_06760) liaF 1233418..1234143 (-) 726 WP_003228510.1 LiaRS two-component regulatory system accessory protein LiaF -
  C2I05_RS06795 (C2I05_06765) liaG 1234177..1235049 (-) 873 WP_120028557.1 DUF4097 domain-containing protein -
  C2I05_RS06800 (C2I05_06770) liaH 1235150..1235827 (-) 678 WP_249847994.1 stress responsive protein LiaH -
  C2I05_RS06805 (C2I05_06775) liaI 1235854..1236234 (-) 381 WP_003243447.1 cell envelope stress-induced membrane anchor protein LiaI -

Sequence

Protein


Download         Length: 211 a.a.        Molecular weight: 23110.77 Da        Isoelectric Point: 5.0313

>NTDB_id=222937 C2I05_RS06780 WP_021480575.1 1231726..1232361(-) (vraR) [Bacillus subtilis strain PK1_2]
MIRVLLIDDHEMVRMGLAAFLEAQPDIEVIGEASDGSEGVRLAAELSPDVILMDLVMEGMDGIEATKQICRELSDPKIIV
LTSFIDDDKVYPVIEAGALSYLLKTSKAAEIADAIRAASKGEPKLESKVAGKVLSRLRHSGENALPHESLTKRELEILCL
IAEGKTNKEIGEELFITIKTVKTHITNILSKLDVSDRTQAAVYAHRNHLVK

Nucleotide


Download         Length: 636 bp        

>NTDB_id=222937 C2I05_RS06780 WP_021480575.1 1231726..1232361(-) (vraR) [Bacillus subtilis strain PK1_2]
GTGATTCGAGTATTATTGATTGATGATCATGAAATGGTCAGAATGGGGCTCGCGGCTTTTTTGGAGGCGCAGCCCGATAT
TGAAGTCATCGGCGAAGCATCGGACGGCAGCGAAGGTGTTCGGCTTGCTGCGGAACTGTCGCCGGATGTCATTTTAATGG
ACCTTGTCATGGAGGGCATGGATGGCATTGAAGCTACAAAGCAAATTTGCCGGGAGCTTTCCGACCCGAAAATTATTGTG
CTCACTAGCTTCATTGATGATGACAAAGTGTACCCGGTTATTGAAGCTGGCGCGCTCAGCTATCTGTTGAAAACCTCAAA
AGCGGCAGAAATCGCCGATGCCATCCGCGCCGCAAGCAAGGGAGAGCCGAAGCTGGAGTCAAAAGTGGCGGGAAAAGTAT
TATCCAGGCTGCGCCACTCAGGTGAAAACGCGCTCCCGCATGAATCGCTGACGAAACGGGAGCTCGAAATACTCTGCCTG
ATCGCAGAAGGAAAGACAAACAAAGAAATAGGCGAGGAACTGTTTATTACGATTAAAACAGTCAAAACACATATTACCAA
TATTTTATCAAAGCTGGATGTCAGTGACCGGACGCAGGCGGCGGTGTACGCGCATCGAAATCATCTCGTCAAATAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(148-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.857

99.526

0.526
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.408