Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   A6J31_RS11160 Genome accession   NZ_CP020431
Coordinates   2165487..2166806 (+) Length   439 a.a.
NCBI ID   WP_080611205.1    Uniprot ID   A0A1V0GGB7
Organism   Streptococcus sp. FDAARGOS_192     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2160487..2171806
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J31_RS11135 (A6J31_11075) - 2161325..2162089 (+) 765 WP_002883723.1 ABC transporter ATP-binding protein -
  A6J31_RS11140 (A6J31_11080) - 2162089..2162799 (+) 711 WP_080611202.1 ABC transporter ATP-binding protein -
  A6J31_RS11145 (A6J31_11085) - 2162934..2163593 (+) 660 WP_038675333.1 CBS and ACT domain-containing protein -
  A6J31_RS11150 (A6J31_11090) cysK 2163778..2164704 (-) 927 WP_002883742.1 cysteine synthase A -
  A6J31_RS11155 (A6J31_11095) - 2164806..2165432 (-) 627 WP_080611204.1 YigZ family protein -
  A6J31_RS11160 (A6J31_11100) comFA/cflA 2165487..2166806 (+) 1320 WP_080611205.1 DEAD/DEAH box helicase Machinery gene
  A6J31_RS11165 (A6J31_11105) - 2166787..2167449 (+) 663 WP_080611207.1 ComF family protein -
  A6J31_RS11170 (A6J31_11110) hpf 2167528..2168076 (+) 549 WP_080611208.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 50525.41 Da        Isoelectric Point: 8.8671

>NTDB_id=222918 A6J31_RS11160 WP_080611205.1 2165487..2166806(+) (comFA/cflA) [Streptococcus sp. FDAARGOS_192]
MVPKEYYGRLFTKEQLPVDYHSEASTLESMIKVDKQIRCKRCYSQIEEDWQLPEGQYYCRACIVFGRNQEGKELYYFPSK
TSEIEFPVLKWLGELTPYQAEVSENLLVTYQKQKDSLVHAVTGAGKTEMIYKIVAYVLENKGRVAIASPRVDVCRELFLR
MQGDFTCSISLLHAESEPYDGSPLVIATTHQLLKFYQNFDLVIVDEVDAFPFVGNVMLNHAVEQAKKETGRYIYLTATST
LSLEEQVRLGALEKHHLARRFHGNPLVLPKFFWQGRLQKSLMRGKLPRPLVYQIKKQRKSKFPLLIFFPNIAIGEKFTSI
LQNYLPDEKMGFVSSKSEERSATVEQFREKELSILVTTTILERGVTFPQVDVFVCMANHHLYTSSSLIQIGGRVGRSPDR
PTGKLYFFHEGLSKSMLRCREEIKVMNKKGGFNNEVSTM

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=222918 A6J31_RS11160 WP_080611205.1 2165487..2166806(+) (comFA/cflA) [Streptococcus sp. FDAARGOS_192]
ATGGTACCTAAAGAATATTATGGACGACTATTTACGAAAGAACAATTGCCAGTGGACTATCACTCAGAGGCATCAACATT
AGAAAGTATGATAAAGGTCGATAAACAAATTAGATGTAAAAGATGTTACAGTCAGATAGAGGAAGATTGGCAATTACCGG
AAGGTCAGTATTATTGCAGAGCGTGTATTGTCTTTGGCAGAAATCAAGAAGGAAAAGAACTTTATTATTTTCCTTCGAAA
ACATCTGAAATTGAATTTCCTGTTTTGAAGTGGTTGGGAGAACTGACTCCCTATCAAGCTGAGGTCTCAGAGAATCTTTT
AGTAACATATCAAAAACAGAAAGACAGTCTCGTACATGCTGTGACCGGTGCTGGTAAGACCGAGATGATTTATAAAATCG
TTGCCTATGTTCTTGAAAATAAAGGTCGTGTAGCTATTGCAAGTCCTCGGGTTGATGTTTGTCGAGAGTTATTTCTTCGT
ATGCAGGGGGATTTTACTTGTAGTATTTCTTTGCTTCATGCTGAGAGTGAACCATATGATGGAAGTCCGCTTGTAATAGC
TACCACCCATCAACTACTAAAGTTTTACCAGAACTTTGACCTAGTTATCGTTGATGAGGTTGATGCATTCCCTTTTGTAG
GAAATGTCATGTTAAATCATGCTGTGGAGCAGGCAAAGAAGGAAACTGGTCGATATATTTATTTAACAGCGACTTCTACA
TTATCTTTAGAGGAGCAAGTTCGACTTGGAGCTTTAGAAAAGCATCACCTTGCTAGACGTTTCCATGGAAATCCTTTAGT
ACTTCCCAAATTCTTTTGGCAGGGAAGACTACAAAAATCTCTAATGAGAGGCAAGCTTCCAAGACCTCTTGTTTATCAGA
TTAAAAAGCAACGTAAATCCAAATTCCCTCTATTAATCTTTTTTCCAAATATAGCGATAGGTGAAAAGTTCACTAGCATT
CTACAAAACTATCTTCCAGATGAAAAAATGGGCTTTGTTTCCTCAAAAAGTGAGGAGCGTTCAGCTACCGTAGAGCAGTT
CCGGGAAAAAGAGTTATCCATCTTAGTGACAACAACTATCCTTGAACGTGGTGTAACCTTTCCACAAGTAGATGTTTTTG
TTTGTATGGCAAATCATCACTTATACACTAGTTCGAGTCTTATTCAGATAGGAGGTCGAGTTGGAAGATCTCCAGATAGA
CCGACAGGGAAGCTTTATTTCTTTCATGAAGGACTATCCAAATCAATGCTTCGTTGCCGAGAAGAAATAAAAGTTATGAA
TAAAAAAGGAGGATTTAACAATGAAGTGTCTACTATGTAA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(291-396)

Type III restriction enzyme, res subunit (ResIII)

(94-167)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1V0GGB7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

56.381

98.178

0.554
  comFA/cflA Streptococcus pneumoniae D39

56.381

98.178

0.554
  comFA/cflA Streptococcus pneumoniae R6

56.381

98.178

0.554
  comFA/cflA Streptococcus pneumoniae TIGR4

56.381

98.178

0.554
  comFA/cflA Streptococcus mitis NCTC 12261

55.53

98.861

0.549
  comFA/cflA Streptococcus mitis SK321

54.756

98.178

0.538
  comFA Lactococcus lactis subsp. cremoris KW2

45.238

95.672

0.433
  comFA Latilactobacillus sakei subsp. sakei 23K

37.471

99.089

0.371

Multiple sequence alignment