Detailed information    

insolico Bioinformatically predicted

Overview

Name   dsbA1   Type   Machinery gene
Locus tag   A6J51_RS02370 Genome accession   NZ_CP020423
Coordinates   406753..407451 (-) Length   232 a.a.
NCBI ID   WP_002223343.1    Uniprot ID   A0A422SVD5
Organism   Neisseria meningitidis strain FDAARGOS_212     
Function   DNA binding and uptake; interact with PilQ (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 401753..412451
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J51_RS02355 (A6J51_02285) - 401868..403109 (-) 1242 WP_080610935.1 peptidylprolyl isomerase -
  A6J51_RS02360 (A6J51_02290) - 403214..405622 (-) 2409 WP_192941132.1 LPS-assembly protein LptD -
  A6J51_RS02365 (A6J51_02295) amgK 405692..406696 (+) 1005 WP_002223344.1 N-acetylmuramate/N-acetylglucosamine kinase AmgK -
  A6J51_RS02370 (A6J51_02300) dsbA1 406753..407451 (-) 699 WP_002223343.1 thiol:disulfide interchange protein DsbA/DsbL Machinery gene
  A6J51_RS02375 (A6J51_02305) - 407478..407669 (+) 192 WP_002233473.1 hypothetical protein -
  A6J51_RS02380 (A6J51_02310) murJ 407669..409207 (+) 1539 WP_042743351.1 murein biosynthesis integral membrane protein MurJ -
  A6J51_RS14580 - 409211..409342 (+) 132 WP_255304562.1 hypothetical protein -
  A6J51_RS02385 (A6J51_02315) - 409339..410295 (+) 957 WP_080610937.1 YheT family hydrolase -
  A6J51_RS02390 (A6J51_02320) trpC 410344..411126 (+) 783 WP_002231636.1 indole-3-glycerol phosphate synthase TrpC -

Sequence

Protein


Download         Length: 232 a.a.        Molecular weight: 25251.84 Da        Isoelectric Point: 5.1392

>NTDB_id=222753 A6J51_RS02370 WP_002223343.1 406753..407451(-) (dsbA1) [Neisseria meningitidis strain FDAARGOS_212]
MKSRQLALGVAALFALAACDSKVQTSVPADSAPAASAAAAPAGLVEGQNYTVLANPIPQQQAGKVEVLEFFGYFCPHCAH
LEPVLSKHAKSFKDDMYLRTEHVVWQKEMLPLARLAAAVDMAAADSKDVANSHIFDAMVNQKIKLQEPEVLKKWLGEQTA
FDGKKVLAAYESPESQARADKMQELTETFQIDGTPTVIVGGKYKVEFADWESGMNTIDLLADKVREEQKAAQ

Nucleotide


Download         Length: 699 bp        

>NTDB_id=222753 A6J51_RS02370 WP_002223343.1 406753..407451(-) (dsbA1) [Neisseria meningitidis strain FDAARGOS_212]
ATGAAATCCAGACAACTCGCCCTCGGCGTTGCCGCCCTGTTCGCCCTTGCCGCGTGCGACAGCAAAGTCCAAACCAGCGT
CCCCGCCGACAGCGCGCCTGCCGCTTCGGCAGCCGCCGCCCCGGCAGGGCTGGTCGAAGGGCAAAACTATACCGTCCTTG
CCAACCCGATTCCCCAACAGCAGGCAGGCAAAGTCGAAGTCCTTGAGTTTTTCGGCTATTTCTGTCCGCACTGCGCCCAC
CTCGAACCTGTTTTGAGCAAACACGCCAAGTCTTTTAAAGACGATATGTACCTGCGTACCGAGCATGTCGTTTGGCAAAA
AGAAATGCTGCCGCTGGCACGCCTCGCCGCCGCCGTCGATATGGCTGCCGCCGACAGCAAAGATGTGGCGAACAGCCATA
TTTTCGATGCGATGGTCAACCAAAAAATCAAGCTGCAAGAGCCGGAAGTCCTCAAAAAATGGCTGGGCGAACAAACCGCC
TTTGACGGCAAAAAAGTCCTTGCCGCCTACGAGTCCCCCGAAAGCCAGGCGCGCGCCGACAAAATGCAGGAGCTGACCGA
AACCTTCCAAATCGACGGTACGCCCACGGTTATCGTCGGCGGTAAATATAAAGTTGAATTTGCCGACTGGGAGTCCGGTA
TGAACACCATCGACCTTTTGGCGGACAAAGTACGCGAAGAACAAAAAGCCGCGCAGTAA

Domains

Predicted by InterproScan.

Thioredoxin (Thioredoxin_4)

(63-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A422SVD5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dsbA1 Neisseria meningitidis MC58

98.707

100

0.987
  dsbA2 Neisseria meningitidis MC58

76.72

81.466

0.625

Multiple sequence alignment