Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   A6J50_RS14630 Genome accession   NZ_CP020422
Coordinates   856630..857094 (-) Length   154 a.a.
NCBI ID   WP_172595944.1    Uniprot ID   -
Organism   Neisseria meningitidis strain FDAARGOS_211     
Function   DNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 844109..863307 856630..857094 within 0


Gene organization within MGE regions


Location: 844109..863307
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J50_RS04975 (A6J50_04900) neuA 844109..844795 (+) 687 WP_002215295.1 N-acylneuraminate cytidylyltransferase -
  A6J50_RS04980 (A6J50_04905) siaC 844796..845845 (+) 1050 WP_002215299.1 polysialic acid capsule biosynthesis protein SiaC -
  A6J50_RS04985 (A6J50_04910) - 845929..847416 (+) 1488 WP_002215303.1 alpha-2,8-polysialyltransferase family protein -
  A6J50_RS04995 (A6J50_04920) - 847912..848865 (-) 954 WP_002215304.1 DUF6716 putative glycosyltransferase -
  A6J50_RS05000 (A6J50_04930) galE 849248..850267 (+) 1020 WP_080541909.1 UDP-glucose 4-epimerase GalE -
  A6J50_RS05005 (A6J50_04935) rfbB 850383..851450 (+) 1068 WP_080541907.1 dTDP-glucose 4,6-dehydratase -
  A6J50_RS05010 (A6J50_04940) rfbA 851513..852379 (+) 867 WP_080541906.1 glucose-1-phosphate thymidylyltransferase RfbA -
  A6J50_RS05015 (A6J50_04945) rfbC 852424..852981 (+) 558 WP_080541910.1 dTDP-4-dehydrorhamnose 3,5-epimerase -
  A6J50_RS05020 (A6J50_04950) - 853025..855043 (-) 2019 WP_002216177.1 OPT family oligopeptide transporter -
  A6J50_RS05025 (A6J50_04955) dnaJ 855239..856360 (-) 1122 WP_002215274.1 molecular chaperone DnaJ -
  A6J50_RS14625 - 856442..856600 (-) 159 WP_002215272.1 hypothetical protein -
  A6J50_RS14630 comE 856630..857094 (-) 465 WP_172595944.1 ComEA family DNA-binding protein Machinery gene
  A6J50_RS05070 (A6J50_05000) dksA 862891..863307 (-) 417 WP_002238569.1 RNA polymerase-binding protein DksA -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 16592.89 Da        Isoelectric Point: 10.8773

>NTDB_id=222741 A6J50_RS14630 WP_172595944.1 856630..857094(-) (comE) [Neisseria meningitidis strain FDAARGOS_211]
MLYPEKMSGMAGRHLYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASLQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKGPAKPVLPADKK

Nucleotide


Download         Length: 465 bp        

>NTDB_id=222741 A6J50_RS14630 WP_172595944.1 856630..857094(-) (comE) [Neisseria meningitidis strain FDAARGOS_211]
TTGCTTTACCCGGAAAAAATGTCGGGGATGGCGGGACGGCATCTGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACTCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCTGCAGGAGTTGGAGGCGCTGCCGGGCATAGGCCCGGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTAGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCCGTCGGCGCGCCCGCACCAAAAGGCCCAGCCAAACCAGTGCTGCCCGCGGATAAAAAATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(75-133)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74

Multiple sequence alignment