Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   C2H95_RS19880 Genome accession   NZ_CP026037
Coordinates   3842983..3843618 (-) Length   211 a.a.
NCBI ID   WP_021480575.1    Uniprot ID   -
Organism   Bacillus subtilis strain PK5_17     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3837983..3848618
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C2H95_RS19860 (C2H95_19770) yvzF 3839040..3839225 (-) 186 WP_003244599.1 YvzF family protein -
  C2H95_RS19865 (C2H95_19775) gerAA 3839343..3840791 (+) 1449 WP_021480572.1 spore germination receptor protein GerAA -
  C2H95_RS19870 (C2H95_19780) gerAB 3840760..3841857 (+) 1098 WP_021480573.1 spore germination receptor protein GerAB -
  C2H95_RS19875 (C2H95_19785) gerAC 3841854..3842975 (+) 1122 WP_021480574.1 spore germination receptor protein GerAC -
  C2H95_RS19880 (C2H95_19790) vraR 3842983..3843618 (-) 636 WP_021480575.1 two-component system response regulator LiaR Regulator
  C2H95_RS19885 (C2H95_19795) liaS 3843596..3844678 (-) 1083 WP_038829325.1 two-component system sensor histidine kinase LiaS -
  C2H95_RS19890 (C2H95_19800) liaF 3844675..3845400 (-) 726 WP_003228510.1 LiaRS two-component regulatory system accessory protein LiaF -
  C2H95_RS19895 (C2H95_19805) liaG 3845434..3846306 (-) 873 WP_038829326.1 DUF4097 domain-containing protein -
  C2H95_RS19900 (C2H95_19810) liaH 3846407..3847084 (-) 678 WP_015714684.1 stress responsive protein LiaH -
  C2H95_RS19905 (C2H95_19815) liaI 3847111..3847491 (-) 381 WP_038829327.1 cell envelope stress-induced membrane anchor protein LiaI -

Sequence

Protein


Download         Length: 211 a.a.        Molecular weight: 23110.77 Da        Isoelectric Point: 5.0313

>NTDB_id=222731 C2H95_RS19880 WP_021480575.1 3842983..3843618(-) (vraR) [Bacillus subtilis strain PK5_17]
MIRVLLIDDHEMVRMGLAAFLEAQPDIEVIGEASDGSEGVRLAAELSPDVILMDLVMEGMDGIEATKQICRELSDPKIIV
LTSFIDDDKVYPVIEAGALSYLLKTSKAAEIADAIRAASKGEPKLESKVAGKVLSRLRHSGENALPHESLTKRELEILCL
IAEGKTNKEIGEELFITIKTVKTHITNILSKLDVSDRTQAAVYAHRNHLVK

Nucleotide


Download         Length: 636 bp        

>NTDB_id=222731 C2H95_RS19880 WP_021480575.1 3842983..3843618(-) (vraR) [Bacillus subtilis strain PK5_17]
GTGATTCGAGTATTATTGATTGATGATCATGAAATGGTCAGAATGGGGCTCGCGGCTTTTTTGGAGGCGCAGCCCGATAT
TGAAGTCATCGGCGAAGCATCGGACGGCAGCGAAGGTGTTCGGCTTGCTGCGGAACTGTCGCCGGATGTCATTTTAATGG
ACCTTGTCATGGAGGGCATGGATGGCATTGAAGCTACAAAGCAAATTTGCCGGGAGCTTTCCGACCCGAAAATTATTGTG
CTCACTAGCTTCATTGATGATGACAAAGTGTACCCGGTTATTGAAGCTGGCGCGCTCAGCTATCTGTTGAAAACCTCAAA
AGCGGCAGAAATCGCCGATGCCATCCGCGCCGCAAGCAAGGGAGAGCCGAAGCTGGAGTCAAAAGTGGCGGGAAAAGTAT
TATCCAGGCTGCGCCACTCAGGTGAAAACGCGCTCCCGCATGAATCGCTGACGAAACGGGAGCTCGAAATACTCTGCCTG
ATCGCAGAAGGAAAGACAAACAAAGAAATAGGCGAGGAACTGTTTATTACGATTAAAACAGTCAAAACACATATTACCAA
TATTTTATCAAAGCTGGATGTCAGTGACCGGACGCAGGCAGCGGTGTACGCGCATCGAAATCATCTCGTCAAATAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(148-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.857

99.526

0.526
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.408