Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   A6J49_RS14835 Genome accession   NZ_CP020421
Coordinates   2227403..2227777 (-) Length   124 a.a.
NCBI ID   WP_009348628.1    Uniprot ID   -
Organism   Neisseria meningitidis strain FDAARGOS_210     
Function   DNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 2214876..2234013 2227403..2227777 within 0


Gene organization within MGE regions


Location: 2214876..2234013
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J49_RS13000 (A6J49_12555) neuA 2214876..2215562 (+) 687 WP_002215295.1 N-acylneuraminate cytidylyltransferase -
  A6J49_RS13005 (A6J49_12560) siaC 2215563..2216612 (+) 1050 WP_002215299.1 polysialic acid capsule biosynthesis protein SiaC -
  A6J49_RS13010 (A6J49_12565) - 2216755..2218182 (+) 1428 WP_226892954.1 alpha-2,8-polysialyltransferase family protein -
  A6J49_RS13020 (A6J49_12575) - 2218678..2219631 (-) 954 WP_002224754.1 DUF6716 putative glycosyltransferase -
  A6J49_RS13025 (A6J49_12580) galE 2220014..2221033 (+) 1020 WP_002249104.1 UDP-glucose 4-epimerase GalE -
  A6J49_RS13030 (A6J49_12585) rfbB 2221149..2222216 (+) 1068 WP_002224748.1 dTDP-glucose 4,6-dehydratase -
  A6J49_RS13035 (A6J49_12590) rfbA 2222279..2223145 (+) 867 WP_002224747.1 glucose-1-phosphate thymidylyltransferase RfbA -
  A6J49_RS13040 (A6J49_12595) rfbC 2223199..2223756 (+) 558 WP_002220108.1 dTDP-4-dehydrorhamnose 3,5-epimerase -
  A6J49_RS13045 (A6J49_12600) - 2223799..2225817 (-) 2019 WP_002224746.1 OPT family oligopeptide transporter -
  A6J49_RS13050 (A6J49_12605) dnaJ 2226012..2227133 (-) 1122 WP_002215274.1 molecular chaperone DnaJ -
  A6J49_RS14835 comE 2227403..2227777 (-) 375 WP_009348628.1 ComEA family DNA-binding protein Machinery gene
  A6J49_RS13090 (A6J49_12650) dksA 2233597..2234013 (-) 417 WP_002215267.1 RNA polymerase-binding protein DksA -

Sequence

Protein


Download         Length: 124 a.a.        Molecular weight: 13444.25 Da        Isoelectric Point: 10.9392

>NTDB_id=222693 A6J49_RS14835 WP_009348628.1 2227403..2227777(-) (comE) [Neisseria meningitidis strain FDAARGOS_210]
MLCPEKMSVMAGRHPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASQQELEALPGIGPAVLAKLKDQASVGAPAPKGPAKPVLPADKK

Nucleotide


Download         Length: 375 bp        

>NTDB_id=222693 A6J49_RS14835 WP_009348628.1 2227403..2227777(-) (comE) [Neisseria meningitidis strain FDAARGOS_210]
TTGCTTTGCCCGGAAAAAATGTCGGTGATGGCGGGACGGCATCCGTACGGTGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACTCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCAGCAGGAGTTGGAGGCGCTGCCAGGCATAGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGGCTTCCGTCGG
CGCGCCCGCACCAAAAGGCCCAGCCAAACCAGTGCTGCCCGCGGATAAAAAATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Neisseria gonorrhoeae MS11

70.492

98.387

0.694
  comE Neisseria gonorrhoeae MS11

70.492

98.387

0.694
  comE Neisseria gonorrhoeae MS11

70.492

98.387

0.694
  comE Neisseria gonorrhoeae MS11

70.492

98.387

0.694

Multiple sequence alignment