Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   A6J48_RS07885 Genome accession   NZ_CP020420
Coordinates   1329419..1329883 (+) Length   154 a.a.
NCBI ID   WP_010981060.1    Uniprot ID   -
Organism   Neisseria meningitidis strain FDAARGOS_209     
Function   DNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1329584..1348958 1329419..1329883 flank -299


Gene organization within MGE regions


Location: 1329419..1348958
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J48_RS07885 (A6J48_07775) comE 1329419..1329883 (+) 465 WP_010981060.1 ComEA family DNA-binding protein Machinery gene
  A6J48_RS07890 (A6J48_07780) dnaJ 1330152..1331273 (+) 1122 WP_002215274.1 molecular chaperone DnaJ -
  A6J48_RS07895 (A6J48_07785) - 1331469..1333487 (+) 2019 WP_002236572.1 OPT family oligopeptide transporter -
  A6J48_RS07900 (A6J48_07790) rfbC 1333531..1334088 (-) 558 WP_164732759.1 dTDP-4-dehydrorhamnose 3,5-epimerase -
  A6J48_RS07905 (A6J48_07795) rfbA 1334142..1335008 (-) 867 WP_002221803.1 glucose-1-phosphate thymidylyltransferase RfbA -
  A6J48_RS07910 (A6J48_07800) rfbB 1335113..1336138 (-) 1026 WP_002236574.1 dTDP-glucose 4,6-dehydratase -
  A6J48_RS07915 (A6J48_07805) galE 1336254..1337273 (-) 1020 WP_082308721.1 UDP-glucose 4-epimerase GalE -
  A6J48_RS07920 (A6J48_07810) - 1337318..1338181 (-) 864 WP_002236576.1 galactosyltransferase-related protein -
  A6J48_RS07925 (A6J48_07815) - 1338183..1338926 (-) 744 WP_002236577.1 YqiA/YcfP family alpha/beta fold hydrolase -
  A6J48_RS07930 (A6J48_07820) - 1338999..1340636 (-) 1638 WP_002236578.1 stealth family protein -
  A6J48_RS07935 (A6J48_07825) wecB 1340638..1341756 (-) 1119 WP_002236579.1 non-hydrolyzing UDP-N-acetylglucosamine 2-epimerase -
  A6J48_RS07940 (A6J48_07830) ctrA 1341975..1343138 (+) 1164 WP_002236580.1 capsule polysaccharide export outer membrane protein CtrA -
  A6J48_RS07945 (A6J48_07835) - 1343153..1344316 (+) 1164 WP_002236581.1 capsule polysaccharide export inner-membrane protein CtrB -
  A6J48_RS07950 (A6J48_07840) - 1344316..1345113 (+) 798 WP_002236582.1 ABC transporter permease -
  A6J48_RS07955 (A6J48_07845) - 1345110..1345760 (+) 651 WP_002218516.1 ABC transporter ATP-binding protein -
  A6J48_RS07960 (A6J48_07850) - 1345824..1348097 (+) 2274 WP_105182942.1 Tex family protein -
  A6J48_RS07965 (A6J48_07855) - 1348128..1348958 (+) 831 WP_002215283.1 DNA cytosine methyltransferase -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 16529.75 Da        Isoelectric Point: 10.6993

>NTDB_id=222628 A6J48_RS07885 WP_010981060.1 1329419..1329883(+) (comE) [Neisseria meningitidis strain FDAARGOS_209]
MLCPEKMSGMAGQYPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASQQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKGPAKPVLPADKK

Nucleotide


Download         Length: 465 bp        

>NTDB_id=222628 A6J48_RS07885 WP_010981060.1 1329419..1329883(+) (comE) [Neisseria meningitidis strain FDAARGOS_209]
TTGCTTTGCCCGGAAAAAATGTCGGGGATGGCGGGACAGTATCCGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACCCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCAGCAGGAGCTGGAGGCGCTGCCGGGCATAGGCCCTGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTAGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCTGTCGGTGCGCCCGCACCAAAAGGCCCAGCTAAACCAGTGCTGCCCGCGGATAAAAAATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(75-133)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Neisseria gonorrhoeae MS11

94.262

79.221

0.747
  comE Neisseria gonorrhoeae MS11

94.262

79.221

0.747
  comE Neisseria gonorrhoeae MS11

94.262

79.221

0.747
  comE Neisseria gonorrhoeae MS11

94.262

79.221

0.747

Multiple sequence alignment