Detailed information NTG0222625

Bioinformatically predicted

Overview

• Name: pilA
• Type: Machinery gene
• Locus tag: A6J48_RS07435
• Genome accession: NZ_CP020420
• Coordinates: 1252118..1253383 (-)
• Length: 421 a.a.
• NCBI ID: WP_002228837.1
• Uniprot ID: A0AB33TWV1
• Organism: Neisseria meningitidis strain FDAARGOS_209
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1247118..1258383

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6J48_RS07415 (A6J48_07290)	pilC	1247517..1250585 (-)	3069	Protein_1256	PilC family type IV pilus tip adhesin	-
A6J48_RS14300	pilC	1250558..1250683 (-)	126	WP_306807087.1	hypothetical protein	Machinery gene
A6J48_RS07420 (A6J48_07300)	-	1251245..1251529 (-)	285	WP_002246543.1	GIY-YIG nuclease family protein	-
A6J48_RS07435 (A6J48_07315)	pilA	1252118..1253383 (-)	1266	WP_002228837.1	signal recognition particle-docking protein FtsY	Machinery gene
A6J48_RS07445 (A6J48_07325)	msrAB	1253529..1255097 (+)	1569	WP_082308717.1	bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB	-
A6J48_RS07450 (A6J48_07330)	-	1255199..1255684 (-)	486	WP_002221794.1	CinA family protein	-
A6J48_RS07455 (A6J48_07335)	-	1255710..1256558 (-)	849	WP_002215243.1	mechanosensitive ion channel family protein	-
A6J48_RS07460 (A6J48_07340)	-	1256652..1257653 (-)	1002	WP_002220087.1	thiamine ABC transporter substrate-binding protein	-

Sequence

Protein

• Length: 421 a.a.
• Molecular weight: 45201.50 Da
• Isoelectric Point: 4.5585

>NTDB_id=222625 A6J48_RS07435 WP_002228837.1 1252118..1253383(-) (pilA) [Neisseria meningitidis strain FDAARGOS_209]
MFSFFRRKKKQETPAPEEAQVQETAAKAESEVTQIVENIKEEVESLTESVKGQVESAVETVSGAVEQVKETVAEMLSEAE
EAAEKAAEQVEAAKEAVAETVGEAVGQVQEAVATTEEHKLGWAARLKQGLTKSRDKMAKSLAGVFGGGQIDEDLYEELET
VLITSDMGMEATEYLMKDVRDRVSLKGLKDGNELRGALKEALYDLIKPLEKPLVLPETKEPFVIMLAGINGAGKTTSIGK
LAKYFQAQGKSVLLAAGDTFRAAAREQLQAWGERNNVTVISQTTGDSAAVCFDAVQAAKARGIDIVLADTAGRLPTQLHL
MEEIKKVKRVLQKAMPDAPHEIIVVLDANIGQNAVNQVKAFDDALGLTGLIVTKLDGTAKGGILAALASDRPVPVRYIGV
GEGIDDLRPFDARAFVDALLD

Nucleotide

• Length: 1266 bp

>NTDB_id=222625 A6J48_RS07435 WP_002228837.1 1252118..1253383(-) (pilA) [Neisseria meningitidis strain FDAARGOS_209]
ATGTTCAGCTTCTTCCGTCGCAAGAAAAAACAGGAAACGCCGGCTCCCGAGGAGGCTCAAGTTCAGGAAACTGCAGCAAA
AGCAGAATCCGAAGTTACTCAAATAGTTGAAAATATTAAAGAAGAAGTCGAATCTTTAACGGAAAGCGTCAAAGGGCAGG
TCGAATCGGCTGTTGAAACCGTCAGCGGTGCGGTTGAACAGGTAAAGGAAACCGTTGCCGAGATGCTGTCTGAAGCAGAG
GAAGCGGCGGAAAAAGCAGCGGAACAAGTCGAAGCGGCAAAAGAAGCCGTTGCCGAAACCGTCGGCGAGGCTGTCGGGCA
AGTTCAAGAAGCCGTTGCGACAACTGAAGAACACAAGCTCGGTTGGGCGGCGCGTTTGAAACAAGGTTTGACCAAATCGC
GCGACAAAATGGCGAAATCGCTGGCGGGCGTGTTCGGCGGCGGACAAATCGACGAAGATTTGTACGAAGAGCTGGAAACC
GTGCTGATTACCAGCGATATGGGCATGGAAGCCACCGAATACCTGATGAAAGACGTGCGCGACCGCGTCAGCCTCAAAGG
GCTGAAAGACGGCAACGAATTGCGCGGCGCGTTGAAAGAAGCCTTGTACGACCTGATTAAGCCTCTGGAGAAACCTTTGG
TTTTGCCCGAAACCAAAGAGCCGTTTGTCATCATGCTTGCCGGCATCAACGGCGCGGGCAAAACCACGTCTATCGGTAAA
CTCGCCAAATATTTCCAAGCGCAGGGCAAATCTGTGCTGCTTGCCGCCGGCGACACCTTCCGCGCCGCCGCCCGTGAGCA
GCTTCAAGCTTGGGGCGAACGCAACAACGTAACCGTGATTTCGCAAACCACGGGCGATTCCGCCGCCGTGTGCTTCGATG
CCGTCCAAGCCGCCAAAGCGCGCGGCATCGACATTGTGCTGGCCGACACCGCCGGCCGCCTGCCCACGCAGCTTCATTTG
ATGGAAGAAATCAAAAAAGTGAAACGCGTGCTGCAAAAAGCCATGCCCGACGCGCCGCACGAAATCATCGTCGTGCTTGA
TGCCAACATCGGGCAAAACGCCGTCAACCAAGTCAAAGCCTTTGACGACGCATTAGGGCTGACCGGTTTAATCGTGACCA
AACTCGACGGCACGGCAAAAGGCGGCATCCTCGCCGCGCTTGCCTCCGACCGCCCCGTCCCCGTCCGCTATATCGGCGTG
GGCGAAGGCATAGACGATTTGCGCCCGTTTGACGCGCGCGCGTTTGTGGACGCACTGCTGGATTGA

Domains

Predicted by InterproScan.

• SRP54-type protein, GTPase domain (SRP54) (221-420)

• SRP54-type protein, helical bundle domain (SRP54_N) (136-202)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilA	Neisseria gonorrhoeae MS11	94.537	100	0.945