Detailed information NTG0222566

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: A6J46_RS03335
• Genome accession: NZ_CP020419
• Coordinates: 542885..543745 (-)
• Length: 286 a.a.
• NCBI ID: WP_003689814.1
• Uniprot ID: A0AA44U9R8
• Organism: Neisseria gonorrhoeae strain FDAARGOS_207
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 537885..548745

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6J46_RS03290 (A6J46_03265)	rplU	537998..538306 (-)	309	WP_003691838.1	50S ribosomal protein L21	-
A6J46_RS03300 (A6J46_03275)	-	538530..539504 (+)	975	WP_003689819.1	polyprenyl synthetase family protein	-
A6J46_RS03305 (A6J46_03280)	-	539508..539954 (+)	447	WP_003689818.1	DUF441 domain-containing protein	-
A6J46_RS03320 (A6J46_03290)	pilF	540292..541968 (+)	1677	WP_003689817.1	type IV-A pilus assembly ATPase PilB	Machinery gene
A6J46_RS03325 (A6J46_03295)	-	542054..542263 (-)	210	WP_003696096.1	DNA gyrase inhibitor YacG	-
A6J46_RS03330 (A6J46_03300)	coaE	542256..542888 (-)	633	WP_003689816.1	dephospho-CoA kinase	-
A6J46_RS03335 (A6J46_03305)	pilD	542885..543745 (-)	861	WP_003689814.1	A24 family peptidase	Machinery gene
A6J46_RS03340 (A6J46_03310)	pilG	543819..545051 (-)	1233	WP_003689811.1	type 4 pilus assembly protein PilG	Machinery gene
A6J46_RS03350 (A6J46_03320)	pgi	545560..547203 (+)	1644	WP_082298666.1	glucose-6-phosphate isomerase	-
A6J46_RS03355 (A6J46_03325)	dapD	547413..548234 (+)	822	WP_003689804.1	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31332.34 Da
• Isoelectric Point: 8.9561

>NTDB_id=222566 A6J46_RS03335 WP_003689814.1 542885..543745(-) (pilD) [Neisseria gonorrhoeae strain FDAARGOS_207]
MSDLSVLSPFAVPLAAVLGLLVGSFLNVVIYRVPVMMERGWTVFAKEHLNLPLTDDESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYSSLWLLCAVYKLLTGKTGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGRHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVR

Nucleotide

• Length: 861 bp

>NTDB_id=222566 A6J46_RS03335 WP_003689814.1 542885..543745(-) (pilD) [Neisseria gonorrhoeae strain FDAARGOS_207]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCAGTTTTGGGGCTGCTGGTCGGCAGCTTCCTGAA
TGTCGTCATTTACCGCGTACCCGTTATGATGGAACGCGGCTGGACGGTATTTGCCAAAGAACATTTAAACCTGCCGCTGA
CCGACGATGAAAGCCGTACCTTCAACCTGATGAAGCCGGATTCCTGCTGTCCCAAATGCCGTGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGTTACCTGCTCCTGCGCGGCAAATGCGCTTCCTGCCAAACCAAAATCAGCATACGTTATCC
CTTAATCGAGCTGCTGACCGGCGTATTGTTCGGGCTGGTCGCCTGGCAATACGGCTGGTCTTGGATTACGCTGGGCGGTT
TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACATTACCC
TTGATCTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATAGTTCATTATGGCTCTTATGTGCAGTGTATAAACTGCTCACAGGAAAAACCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCTCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCGGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGAGATGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

• Type IV leader peptidase family (Peptidase_A24) (134-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	100	100	1
pilD	Vibrio cholerae strain A1552	44.792	100	0.451
pilD	Vibrio campbellii strain DS40M4	45.652	96.503	0.441
pilD	Acinetobacter baumannii D1279779	47.727	92.308	0.441
pilD	Acinetobacter nosocomialis M2	47.727	92.308	0.441