Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   C2H93_RS14630 Genome accession   NZ_CP026036
Coordinates   2854880..2855515 (-) Length   211 a.a.
NCBI ID   WP_021480575.1    Uniprot ID   -
Organism   Bacillus subtilis strain PK5_16     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2849880..2860515
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C2H93_RS14610 (C2H93_14610) yvzF 2850937..2851122 (-) 186 WP_003244599.1 YvzF family protein -
  C2H93_RS14615 (C2H93_14615) gerAA 2851240..2852688 (+) 1449 WP_021480572.1 spore germination receptor protein GerAA -
  C2H93_RS14620 (C2H93_14620) gerAB 2852657..2853754 (+) 1098 WP_021480573.1 spore germination receptor protein GerAB -
  C2H93_RS14625 (C2H93_14625) gerAC 2853751..2854872 (+) 1122 WP_021480574.1 spore germination receptor protein GerAC -
  C2H93_RS14630 (C2H93_14630) vraR 2854880..2855515 (-) 636 WP_021480575.1 two-component system response regulator LiaR Regulator
  C2H93_RS14635 (C2H93_14635) liaS 2855493..2856575 (-) 1083 WP_003244464.1 two-component system sensor histidine kinase LiaS -
  C2H93_RS14640 (C2H93_14640) liaF 2856572..2857297 (-) 726 WP_003228510.1 LiaRS two-component regulatory system accessory protein LiaF -
  C2H93_RS14645 (C2H93_14645) liaG 2857331..2858203 (-) 873 WP_120028557.1 DUF4097 domain-containing protein -
  C2H93_RS14650 (C2H93_14650) liaH 2858304..2858981 (-) 678 WP_015714684.1 stress responsive protein LiaH -
  C2H93_RS14655 (C2H93_14655) liaI 2859008..2859388 (-) 381 WP_003228504.1 cell envelope stress-induced membrane anchor protein LiaI -

Sequence

Protein


Download         Length: 211 a.a.        Molecular weight: 23110.77 Da        Isoelectric Point: 5.0313

>NTDB_id=222549 C2H93_RS14630 WP_021480575.1 2854880..2855515(-) (vraR) [Bacillus subtilis strain PK5_16]
MIRVLLIDDHEMVRMGLAAFLEAQPDIEVIGEASDGSEGVRLAAELSPDVILMDLVMEGMDGIEATKQICRELSDPKIIV
LTSFIDDDKVYPVIEAGALSYLLKTSKAAEIADAIRAASKGEPKLESKVAGKVLSRLRHSGENALPHESLTKRELEILCL
IAEGKTNKEIGEELFITIKTVKTHITNILSKLDVSDRTQAAVYAHRNHLVK

Nucleotide


Download         Length: 636 bp        

>NTDB_id=222549 C2H93_RS14630 WP_021480575.1 2854880..2855515(-) (vraR) [Bacillus subtilis strain PK5_16]
GTGATTCGAGTATTATTGATTGATGATCATGAAATGGTCAGAATGGGGCTCGCGGCTTTTTTGGAGGCGCAGCCCGATAT
TGAAGTCATCGGCGAAGCATCGGACGGCAGCGAAGGTGTTCGGCTTGCTGCGGAACTGTCGCCGGATGTCATTTTAATGG
ACCTTGTCATGGAGGGCATGGATGGCATTGAAGCTACAAAGCAAATTTGCCGGGAGCTTTCCGACCCGAAAATTATTGTG
CTCACTAGCTTCATTGATGATGACAAAGTGTACCCGGTTATTGAAGCTGGCGCGCTCAGCTATCTGTTGAAAACCTCAAA
AGCGGCAGAAATCGCCGATGCCATCCGCGCCGCAAGCAAGGGAGAGCCGAAGCTGGAGTCAAAAGTGGCGGGAAAAGTAT
TATCCAGGCTGCGCCACTCAGGTGAAAACGCGCTCCCGCATGAATCGCTGACGAAACGGGAGCTCGAAATACTCTGCCTG
ATCGCAGAAGGAAAGACAAACAAAGAAATAGGCGAGGAACTGTTTATTACGATTAAAACAGTCAAAACACATATTACCAA
TATTTTATCAAAGCTGGATGTCAGTGACCGGACGCAGGCGGCGGTGTACGCGCATCGAAATCATCTCGTCAAATAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(148-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.857

99.526

0.526
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.408