Detailed information NTG0222466

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: A6J43_RS01130
• Genome accession: NZ_CP020415
• Coordinates: 185114..185974 (-)
• Length: 286 a.a.
• NCBI ID: WP_003689814.1
• Uniprot ID: A0AA44U9R8
• Organism: Neisseria gonorrhoeae strain FDAARGOS_204
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 180114..190974

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6J43_RS01085 (A6J43_01050)	rplU	180227..180535 (-)	309	WP_003691838.1	50S ribosomal protein L21	-
A6J43_RS01095 (A6J43_01060)	-	180759..181733 (+)	975	WP_003689819.1	polyprenyl synthetase family protein	-
A6J43_RS01100 (A6J43_01065)	-	181737..182183 (+)	447	WP_003689818.1	DUF441 domain-containing protein	-
A6J43_RS01115 (A6J43_01075)	pilF	182521..184197 (+)	1677	WP_003689817.1	type IV-A pilus assembly ATPase PilB	Machinery gene
A6J43_RS01120 (A6J43_01080)	-	184283..184492 (-)	210	WP_003696096.1	DNA gyrase inhibitor YacG	-
A6J43_RS01125 (A6J43_01085)	coaE	184485..185117 (-)	633	WP_003689816.1	dephospho-CoA kinase	-
A6J43_RS01130 (A6J43_01090)	pilD	185114..185974 (-)	861	WP_003689814.1	A24 family peptidase	Machinery gene
A6J43_RS01135 (A6J43_01095)	pilG	186048..187280 (-)	1233	WP_003689811.1	type 4 pilus assembly protein PilG	Machinery gene
A6J43_RS01145 (A6J43_01105)	pgi	187790..189433 (+)	1644	WP_003697594.1	glucose-6-phosphate isomerase	-
A6J43_RS01150 (A6J43_01110)	dapD	189643..190464 (+)	822	WP_003689804.1	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31332.34 Da
• Isoelectric Point: 8.9561

>NTDB_id=222466 A6J43_RS01130 WP_003689814.1 185114..185974(-) (pilD) [Neisseria gonorrhoeae strain FDAARGOS_204]
MSDLSVLSPFAVPLAAVLGLLVGSFLNVVIYRVPVMMERGWTVFAKEHLNLPLTDDESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYSSLWLLCAVYKLLTGKTGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGRHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVR

Nucleotide

• Length: 861 bp

>NTDB_id=222466 A6J43_RS01130 WP_003689814.1 185114..185974(-) (pilD) [Neisseria gonorrhoeae strain FDAARGOS_204]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCAGTTTTGGGGCTGCTGGTCGGCAGCTTCCTGAA
TGTCGTCATTTACCGCGTACCCGTTATGATGGAACGCGGCTGGACGGTATTTGCCAAAGAACATTTAAACCTGCCGCTGA
CCGACGATGAAAGCCGTACCTTCAACCTGATGAAGCCGGATTCCTGCTGTCCCAAATGCCGTGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGTTACCTGCTCCTGCGCGGCAAATGCGCTTCCTGCCAAACCAAAATCAGCATACGTTATCC
CTTAATCGAGCTGCTGACCGGCGTATTGTTCGGGCTGGTCGCCTGGCAATACGGCTGGTCTTGGATTACGCTGGGCGGTT
TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACATTACCC
TTGATCTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATAGTTCATTATGGCTCTTATGTGCAGTGTATAAACTGCTCACAGGAAAAACCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCTCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCGGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGAGATGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

• Type IV leader peptidase family (Peptidase_A24) (134-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	100	100	1
pilD	Vibrio cholerae strain A1552	44.792	100	0.451
pilD	Vibrio campbellii strain DS40M4	45.652	96.503	0.441
pilD	Acinetobacter baumannii D1279779	47.727	92.308	0.441
pilD	Acinetobacter nosocomialis M2	47.727	92.308	0.441