Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   A6J54_RS14535 Genome accession   NZ_CP020402
Coordinates   421240..421704 (-) Length   154 a.a.
NCBI ID   WP_172595944.1    Uniprot ID   -
Organism   Neisseria meningitidis strain FDAARGOS_215     
Function   DNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 408719..427917 421240..421704 within 0


Gene organization within MGE regions


Location: 408719..427917
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J54_RS02380 (A6J54_02325) neuA 408719..409405 (+) 687 WP_002215295.1 N-acylneuraminate cytidylyltransferase -
  A6J54_RS02385 (A6J54_02330) siaC 409406..410455 (+) 1050 WP_002215299.1 polysialic acid capsule biosynthesis protein SiaC -
  A6J54_RS02390 (A6J54_02335) - 410539..412026 (+) 1488 WP_002215303.1 alpha-2,8-polysialyltransferase family protein -
  A6J54_RS02400 (A6J54_02345) - 412522..413475 (-) 954 WP_002215304.1 DUF6716 putative glycosyltransferase -
  A6J54_RS02410 (A6J54_02355) galE 413858..414877 (+) 1020 WP_080541909.1 UDP-glucose 4-epimerase GalE -
  A6J54_RS02415 (A6J54_02360) rfbB 414993..416060 (+) 1068 WP_080541907.1 dTDP-glucose 4,6-dehydratase -
  A6J54_RS02420 (A6J54_02365) rfbA 416123..416989 (+) 867 WP_080541906.1 glucose-1-phosphate thymidylyltransferase RfbA -
  A6J54_RS02425 (A6J54_02370) rfbC 417034..417591 (+) 558 WP_080541910.1 dTDP-4-dehydrorhamnose 3,5-epimerase -
  A6J54_RS02430 (A6J54_02375) - 417635..419653 (-) 2019 WP_002216177.1 OPT family oligopeptide transporter -
  A6J54_RS02435 (A6J54_02380) dnaJ 419849..420970 (-) 1122 WP_002215274.1 molecular chaperone DnaJ -
  A6J54_RS14530 - 421052..421210 (-) 159 WP_002215272.1 hypothetical protein -
  A6J54_RS14535 comE 421240..421704 (-) 465 WP_172595944.1 ComEA family DNA-binding protein Machinery gene
  A6J54_RS02480 (A6J54_02425) dksA 427501..427917 (-) 417 WP_002238569.1 RNA polymerase-binding protein DksA -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 16592.89 Da        Isoelectric Point: 10.8773

>NTDB_id=222236 A6J54_RS14535 WP_172595944.1 421240..421704(-) (comE) [Neisseria meningitidis strain FDAARGOS_215]
MLYPEKMSGMAGRHLYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASLQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKGPAKPVLPADKK

Nucleotide


Download         Length: 465 bp        

>NTDB_id=222236 A6J54_RS14535 WP_172595944.1 421240..421704(-) (comE) [Neisseria meningitidis strain FDAARGOS_215]
TTGCTTTACCCGGAAAAAATGTCGGGGATGGCGGGACGGCATCTGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACTCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCTGCAGGAGTTGGAGGCGCTGCCGGGCATAGGCCCGGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTAGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCCGTCGGCGCGCCCGCACCAAAAGGCCCAGCCAAACCAGTGCTGCCCGCGGATAAAAAATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(75-133)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74

Multiple sequence alignment