Detailed information NTG0221817

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: THSYN_RS00910
• Genome accession: NZ_CP020370
• Coordinates: 211865..213211 (+)
• Length: 448 a.a.
• NCBI ID: WP_100917473.1
• Uniprot ID: A0A2K8U2A0
• Organism: Candidatus Thiodictyon syntrophicum strain Cad16T
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 206865..218211

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
THSYN_RS00895 (THSYN_00880)	sucD	207776..208651 (-)	876	WP_100917470.1	succinate--CoA ligase subunit alpha	-
THSYN_RS00900 (THSYN_00885)	sucC	208662..209831 (-)	1170	WP_100917471.1	ADP-forming succinate--CoA ligase subunit beta	-
THSYN_RS00905 (THSYN_00890)	-	210065..211723 (+)	1659	WP_100917472.1	sensor histidine kinase	-
THSYN_RS00910 (THSYN_00895)	pilR	211865..213211 (+)	1347	WP_100917473.1	sigma-54-dependent transcriptional regulator	Regulator
THSYN_RS00915 (THSYN_00900)	argA	213234..214622 (+)	1389	WP_100917474.1	amino-acid N-acetyltransferase	-
THSYN_RS00920 (THSYN_00905)	-	214731..216458 (+)	1728	WP_100917475.1	OmpA family protein	-

Sequence

Protein

• Length: 448 a.a.
• Molecular weight: 49023.28 Da
• Isoelectric Point: 6.2048

>NTDB_id=221817 THSYN_RS00910 WP_100917473.1 211865..213211(+) (pilR) [Candidatus Thiodictyon syntrophicum strain Cad16T]
MNKAHALVVDDEADILDLLKITLGRMDVQATTAMTVAEAKTALQARRYDLCLTDMNLPDGSGIDLVRFIVERHPDLPVAM
ITAHGSMESAVAAMKAGAFDFVSKPVDLQLLRRLVGSALKLRTHGGAAEARTESGTRLLGDSPKVEEIRRLVAKLARNQA
PVFITGESGTGKELAARLIHAQGPRAEGDFVAVNCGAIPQELVESELFGHKKGSFTGAVADKEGLFQAAEGGTLFLDEVA
DLPLPAQVKLLRAIQEKSVRPVGAQQELAVDVRIISASHRDLNEEVEKGRFRQDLFYRINVIEMRMPALREHPQDIPALA
ARIMERIARQHADREAMRLSEEAVEALARHPFPGNVRELENVLERATALCDGSIIGAHDLYLPQTEAQVAVGSHADPEVP
LEDYLGEIERHAILKALDDTRWNRTAAAKKLGMTLRALRYRLAKLGIE

Nucleotide

• Length: 1347 bp

>NTDB_id=221817 THSYN_RS00910 WP_100917473.1 211865..213211(+) (pilR) [Candidatus Thiodictyon syntrophicum strain Cad16T]
ATGAATAAGGCCCACGCCCTCGTCGTCGATGACGAGGCCGACATCCTCGACCTGCTCAAGATCACCTTGGGTCGCATGGA
CGTGCAGGCAACCACGGCCATGACGGTGGCCGAGGCCAAGACGGCGCTGCAGGCACGGCGCTACGACCTGTGCCTCACCG
ACATGAACCTGCCGGACGGCAGCGGGATCGATCTGGTGCGCTTCATCGTCGAGCGCCACCCCGATCTGCCGGTCGCCATG
ATCACTGCCCACGGCAGCATGGAATCGGCCGTCGCCGCGATGAAGGCCGGCGCCTTCGACTTCGTCTCCAAGCCGGTGGA
TTTGCAACTGCTGCGCCGCCTGGTGGGATCGGCGCTCAAGTTGCGCACCCACGGCGGCGCGGCGGAGGCGCGCACCGAGA
GCGGCACCCGCCTGCTCGGGGACTCCCCCAAGGTGGAGGAGATCCGCCGCCTCGTCGCCAAGCTGGCGCGCAATCAGGCG
CCGGTCTTCATTACCGGTGAGAGCGGCACCGGCAAGGAACTGGCGGCGCGCCTGATCCACGCCCAGGGCCCGCGGGCGGA
GGGCGATTTCGTGGCGGTCAACTGTGGTGCCATCCCCCAGGAGCTGGTGGAGAGCGAACTGTTCGGCCACAAGAAGGGCA
GCTTCACCGGTGCGGTGGCGGACAAGGAGGGGCTGTTCCAGGCGGCCGAGGGCGGCACCCTGTTTCTGGACGAGGTGGCT
GACCTGCCGCTGCCCGCCCAGGTCAAGCTCCTGCGGGCCATCCAGGAGAAGAGCGTGCGGCCGGTGGGGGCCCAGCAGGA
GCTGGCGGTGGATGTGCGCATCATCAGCGCGAGCCACCGGGATCTGAACGAGGAGGTGGAGAAGGGCCGCTTCCGTCAGG
ACCTCTTCTACCGCATCAATGTGATCGAGATGCGCATGCCCGCGCTGCGCGAACACCCCCAGGACATCCCGGCCCTGGCC
GCGCGCATCATGGAGCGCATCGCCCGCCAGCACGCCGACCGCGAGGCCATGAGGCTCTCGGAGGAGGCGGTGGAGGCGCT
CGCCCGTCACCCCTTCCCAGGCAATGTGCGCGAGTTGGAGAATGTGCTGGAGCGCGCCACCGCGCTCTGCGACGGCTCCA
TCATCGGCGCCCATGACCTCTACCTGCCGCAGACCGAGGCCCAGGTCGCGGTCGGGTCGCACGCGGACCCCGAGGTCCCC
CTGGAGGACTACCTGGGGGAGATCGAGCGCCATGCCATCCTCAAGGCCCTGGACGACACCCGCTGGAACCGCACCGCGGC
CGCCAAGAAGCTCGGCATGACGCTGCGTGCCTTGCGCTATCGCCTGGCCAAGCTCGGGATCGAATAG

Domains

Predicted by InterproScan.

• Sigma-54 interaction domain (Sigma54_activat) (139-304)

• Response regulator receiver domain (Response_reg) (7-113)

• Bacterial regulatory protein, Fis family (HTH_8) (405-445)

3D structure

• AlphaFold DB: A0A2K8U2A0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	61.024	100	0.612
pilR	Acinetobacter baumannii strain A118	48.366	100	0.496