Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   SAS_RS08500 Genome accession   NC_002953
Coordinates   1724814..1726076 (-) Length   420 a.a.
NCBI ID   WP_000472304.1    Uniprot ID   Q8NW72
Organism   Staphylococcus aureus subsp. aureus MSSA476     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1719814..1731076
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SAS_RS08475 (SAS1598) - 1720012..1720680 (-) 669 WP_000805950.1 uroporphyrinogen-III synthase -
  SAS_RS08480 (SAS1599) hemC 1720702..1721628 (-) 927 WP_001230226.1 hydroxymethylbilane synthase -
  SAS_RS08485 (SAS1600) ccsA 1721670..1722485 (-) 816 WP_001157329.1 cytochrome c biogenesis protein -
  SAS_RS08490 (SAS1601) hemA 1722507..1723853 (-) 1347 WP_000545451.1 glutamyl-tRNA reductase -
  SAS_RS08495 (SAS1602) yihA 1724070..1724660 (-) 591 WP_000867697.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  SAS_RS08500 (SAS1603) clpX 1724814..1726076 (-) 1263 WP_000472304.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  SAS_RS08505 (SAS1604) tig 1726227..1727528 (-) 1302 WP_000127573.1 trigger factor -
  SAS_RS08510 - 1727576..1727686 (-) 111 WP_001790560.1 hypothetical protein -
  SAS_RS08515 (SAS1605) - 1727691..1728620 (-) 930 WP_001280022.1 hypothetical protein -
  SAS_RS08520 (SAS1606) - 1728639..1729247 (-) 609 WP_000032650.1 NUDIX domain-containing protein -
  SAS_RS08530 (SAS1607) rplT 1729389..1729745 (-) 357 WP_001138360.1 50S ribosomal protein L20 -
  SAS_RS08535 (SAS1608) rpmI 1729792..1729992 (-) 201 WP_001125540.1 50S ribosomal protein L35 -
  SAS_RS08540 (SAS1609) infC 1730021..1730548 (-) 528 WP_001791162.1 translation initiation factor IF-3 -

Sequence

Protein


Download         Length: 420 a.a.        Molecular weight: 46296.49 Da        Isoelectric Point: 4.2827

>NTDB_id=22166 SAS_RS08500 WP_000472304.1 1724814..1726076(-) (clpX) [Staphylococcus aureus subsp. aureus MSSA476]
MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAMTELPTPKEIMDHLNEYVIGQEK
AKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENIL
LRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTN
ILFILGGAFDGIEEVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNIL
TQPKNALVKQYTKMLELDNVDLEFTEEALSAISEKAIERKTGARGLRSIIEESLIDIMFDVPSNENVTKVVITAQTINEE
TEPELYDAEGNLINNSKTSA

Nucleotide


Download         Length: 1263 bp        

>NTDB_id=22166 SAS_RS08500 WP_000472304.1 1724814..1726076(-) (clpX) [Staphylococcus aureus subsp. aureus MSSA476]
ATGTTTAAATTCAATGAAGATGAAGAAAATTTGAAATGCTCTTTCTGCGGAAAAGACCAAGATCAAGTAAAAAAACTTGT
AGCAGGAAGTGGTGTATATATTTGTAATGAGTGTATTGAATTATGCTCAGAAATCGTCGAAGAAGAATTAGCTCAAAACA
CTTCTGAAGCGATGACAGAATTACCTACTCCTAAAGAAATTATGGATCATTTAAACGAATATGTTATTGGTCAAGAAAAA
GCTAAAAAATCTTTAGCTGTAGCTGTTTATAACCACTATAAGCGTATTCAACAATTAGGACCAAAAGAAGATGATGTTGA
ATTACAAAAAAGTAACATTGCATTAATTGGGCCAACAGGTAGTGGTAAAACATTATTAGCTCAAACATTAGCCAAGACGT
TGAATGTACCATTTGCAATTGCAGATGCGACAAGTTTAACTGAAGCTGGTTATGTAGGCGATGATGTTGAAAATATCTTG
TTGAGATTAATTCAAGCAGCTGACTTTGACATTGATAAAGCCGAAAAAGGTATTATTTATGTAGATGAAATTGATAAAAT
TGCACGTAAATCTGAAAACACATCTATAACACGTGACGTTTCAGGTGAAGGTGTTCAACAAGCATTGCTTAAAATCTTAG
AAGGTACGACTGCAAGTGTTCCGCCACAAGGTGGACGCAAACATCCAAACCAAGAAATGATTCAAATTGATACAACAAAT
ATCTTATTTATTCTTGGTGGTGCCTTTGATGGTATTGAAGAAGTGATTAAGCGCCGTCTTGGTGAAAAAGTTATTGGTTT
CTCAAGCAATGAAGCTGATAAATATGACGAACAAGCATTATTAGCACAAATTCGCCCAGAAGATTTGCAAGCCTATGGTT
TGATTCCTGAATTTATCGGACGTGTGCCAATTGTAGCTAATTTAGAAACATTAGATGTAACTGCGTTGAAAAACATCTTA
ACGCAACCTAAAAATGCACTTGTGAAACAATATACTAAAATGCTGGAATTAGATAATGTGGATTTAGAGTTCACTGAAGA
AGCTTTATCAGCAATTAGTGAAAAAGCAATTGAAAGAAAAACAGGTGCGCGTGGTTTACGTTCAATCATAGAAGAATCGT
TAATCGATATTATGTTTGATGTGCCTTCTAACGAAAATGTAACGAAGGTAGTTATTACAGCACAAACAATTAATGAAGAA
ACTGAACCAGAACTATACGACGCAGAAGGCAATTTAATTAATAATAGTAAAACATCAGCTTAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-305)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8NW72

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

66.917

95

0.636
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.456

94.048

0.531

Multiple sequence alignment