Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   BLMD_RS06645 Genome accession   NZ_CP020352
Coordinates   1331889..1332527 (+) Length   212 a.a.
NCBI ID   WP_003180627.1    Uniprot ID   A0A6I7TLB4
Organism   Bacillus paralicheniformis strain MDJK30     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1326889..1337527
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BLMD_RS06620 (BLMD_06620) - 1327537..1328604 (+) 1068 WP_020450934.1 ABC transporter ATP-binding protein -
  BLMD_RS06625 (BLMD_06625) - 1328606..1329529 (+) 924 WP_080131317.1 ABC transporter ATP-binding protein -
  BLMD_RS06630 (BLMD_06630) - 1329759..1330337 (+) 579 WP_003180619.1 GNAT family N-acetyltransferase -
  BLMD_RS06635 (BLMD_06635) spxA 1330515..1330910 (+) 396 WP_003180621.1 transcriptional regulator SpxA -
  BLMD_RS06640 (BLMD_06640) - 1330941..1331603 (-) 663 WP_020450936.1 TerC family protein -
  BLMD_RS21895 - 1331782..1331907 (+) 126 Protein_1250 hypothetical protein -
  BLMD_RS06645 (BLMD_06645) mecA 1331889..1332527 (+) 639 WP_003180627.1 adaptor protein MecA Regulator
  BLMD_RS06650 (BLMD_06650) - 1332765..1334069 (+) 1305 WP_080131318.1 glycosyl hydrolase family 8 -
  BLMD_RS06655 (BLMD_06655) - 1334292..1335308 (+) 1017 WP_023856657.1 tripartite tricarboxylate transporter substrate binding protein -
  BLMD_RS06660 (BLMD_06660) - 1335411..1335866 (+) 456 WP_048350052.1 tripartite tricarboxylate transporter TctB family protein -
  BLMD_RS06665 (BLMD_06665) - 1335889..1337394 (+) 1506 WP_020450940.1 tripartite tricarboxylate transporter permease -

Sequence

Protein


Download         Length: 212 a.a.        Molecular weight: 25044.99 Da        Isoelectric Point: 4.1840

>NTDB_id=221625 BLMD_RS06645 WP_003180627.1 1331889..1332527(+) (mecA) [Bacillus paralicheniformis strain MDJK30]
MEIERINEHTVKFYISYGDIEDRGFDREEIWYNRERSEELFWEMMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTRAQL
SKDGQKLELPIPEDKKQHVAEESLDALLDDFQKEEQAEEQKLQFVLKFDDFEDLISLSKMSISGCQTTLYSHENRYYLFV
DFSELPDEEVENQLSILLEYASESKTTIHMLKEYGTLIAADHALHTIKKHFA

Nucleotide


Download         Length: 639 bp        

>NTDB_id=221625 BLMD_RS06645 WP_003180627.1 1331889..1332527(+) (mecA) [Bacillus paralicheniformis strain MDJK30]
ATGGAAATCGAAAGAATAAACGAACATACGGTTAAGTTTTATATTTCCTACGGTGATATCGAAGACCGCGGGTTTGACAG
AGAAGAAATTTGGTACAATCGAGAACGCAGTGAAGAGCTTTTTTGGGAAATGATGGACGAAGTGCACGAAGAAGAAGAGT
TTGCCGTTGAAGGCCCCCTTTGGATTCAAGTGCAGGCCCTTGATAAGGGATTGGAAATCATTGTGACAAGAGCTCAGCTG
TCCAAAGACGGACAAAAGCTGGAACTGCCGATTCCTGAAGATAAAAAACAGCATGTAGCAGAAGAAAGCCTTGATGCTTT
GCTTGACGACTTTCAAAAAGAAGAGCAGGCAGAAGAGCAGAAACTGCAGTTTGTTTTAAAGTTTGACGATTTTGAGGATT
TAATCTCACTGTCAAAAATGTCTATCAGCGGCTGCCAAACGACATTGTACTCTCACGAGAACCGCTATTATTTATTCGTG
GATTTCAGTGAACTGCCCGATGAAGAGGTGGAAAACCAGCTGAGCATTCTGCTGGAGTATGCCTCAGAATCAAAGACGAC
GATTCATATGCTGAAAGAGTATGGAACACTGATTGCAGCGGATCATGCTCTTCATACAATAAAAAAGCACTTCGCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-207)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6I7TLB4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

82.028

100

0.84

Multiple sequence alignment