Detailed information NTG0221597

Bioinformatically predicted

Overview

• Name: comQ
• Type: Regulator
• Locus tag: BS11774_RS00565
• Genome accession: NZ_CP026010
• Coordinates: 94966..95826 (-)
• Length: 286 a.a.
• NCBI ID: WP_128422373.1
• Uniprot ID: Q9R9J5
• Organism: Bacillus subtilis strain ATCC 11774
• Function: modification of ComX; production of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 89966..100826

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BS11774_RS00530 (BS11774_00525)	yuxO	89976..90356 (-)	381	WP_017695528.1	hotdog fold thioesterase	-
BS11774_RS00535 (BS11774_00530)	comA	90375..91019 (-)	645	WP_003220716.1	two-component system response regulator ComA	Regulator
BS11774_RS00540 (BS11774_00535)	-	91100..92788 (-)	1689	Protein_81	histidine kinase	-
BS11774_RS00545 (BS11774_00540)	-	92813..94060 (-)	1248	WP_031600262.1	IS256-like element ISBsu2 family transposase	-
BS11774_RS00555 (BS11774_00550)	-	94157..94777 (-)	621	Protein_83	PDZ domain-containing protein	-
BS11774_RS00560 (BS11774_00555)	comX	94789..94953 (-)	165	WP_015384519.1	competence pheromone ComX	-
BS11774_RS00565 (BS11774_00560)	comQ	94966..95826 (-)	861	WP_128422373.1	polyprenyl synthetase family protein	Regulator
BS11774_RS00570 (BS11774_00565)	degQ	96011..96151 (-)	141	WP_003220708.1	degradation enzyme regulation protein DegQ	Regulator
BS11774_RS00575	-	96373..96498 (+)	126	WP_128473219.1	hypothetical protein	-
BS11774_RS00580 (BS11774_00570)	-	96614..96982 (+)	369	WP_017695529.1	hypothetical protein	-
BS11774_RS00585 (BS11774_00575)	pdeH	96958..98187 (-)	1230	WP_024572553.1	cyclic di-GMP phosphodiesterase	-
BS11774_RS00590 (BS11774_00580)	pncB	98324..99796 (-)	1473	WP_003228788.1	nicotinate phosphoribosyltransferase	-
BS11774_RS00595 (BS11774_00585)	pncA	99812..100363 (-)	552	WP_014480709.1	isochorismatase family cysteine hydrolase	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 32618.54 Da
• Isoelectric Point: 4.8309

>NTDB_id=221597 BS11774_RS00565 WP_128422373.1 94966..95826(-) (comQ) [Bacillus subtilis strain ATCC 11774]
MKEIVSQKIMNQDLERYLQNFIESKDTFEFADLALHHYLAFNGQDQKAIEWLAAGIELLILSFDIYDDLEDQDNGSAVWM
KIDSSIALNAVTALYTLSIQVMCQASHEPEFSQEILNFALQSIQGQHDDIVNAPQTEEACLEMIKNKSGALTALPCVMGV
MLATGKYHPIVASYSYELGIIAQIENDYRGLYYLNNDFIQKKNTLAYLYLNKRFNAASAEILSWYENTELFLSLNSKQIK
EKLTEAGVVQYLLVMKHLSLQKLKKEIARLELQENKIKKLITGIIK

Nucleotide

• Length: 861 bp

>NTDB_id=221597 BS11774_RS00565 WP_128422373.1 94966..95826(-) (comQ) [Bacillus subtilis strain ATCC 11774]
ATGAAGGAGATTGTAAGCCAAAAAATAATGAATCAGGACTTGGAACGATATCTTCAGAATTTTATTGAGTCTAAGGATAC
GTTTGAGTTTGCCGATTTGGCTCTTCATCATTATTTAGCTTTTAACGGTCAGGACCAAAAAGCAATCGAATGGCTAGCTG
CCGGAATTGAATTGCTTATACTCTCATTCGATATTTATGATGACTTAGAGGATCAAGATAATGGAAGTGCTGTCTGGATG
AAGATTGACTCGTCAATCGCTTTAAATGCAGTTACAGCTCTTTACACCCTAAGTATACAAGTGATGTGTCAAGCTAGTCA
TGAACCAGAATTTTCACAAGAGATATTGAATTTTGCGTTACAATCAATTCAAGGCCAGCATGATGATATTGTGAATGCGC
CGCAAACGGAAGAAGCCTGTCTTGAAATGATCAAAAATAAATCAGGAGCGCTAACGGCATTGCCCTGTGTAATGGGAGTA
ATGCTGGCAACAGGCAAATACCATCCCATTGTAGCTTCTTATTCTTATGAACTTGGGATTATTGCACAAATCGAAAATGA
TTACCGAGGTTTATATTATCTAAATAACGATTTTATTCAGAAGAAAAACACATTGGCATACTTATACTTAAATAAACGTT
TTAATGCAGCTTCTGCAGAAATCTTGAGTTGGTATGAAAATACTGAGTTGTTCTTATCATTGAATTCCAAACAAATAAAA
GAAAAATTAACTGAGGCAGGCGTAGTGCAATATTTACTTGTAATGAAACACTTGTCATTACAAAAACTAAAGAAAGAAAT
TGCTAGATTAGAATTGCAAGAGAATAAAATAAAAAAATTAATAACAGGAATCATAAAATAA

Domains

Predicted by InterProScan.

• Polyprenyl synthetase (polyprenyl_synt) (40-197)

3D structure

• AlphaFold DB: Q9R9J5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comQ	Bacillus subtilis subsp. subtilis str. 168	45.423	99.301	0.451