Detailed information NTG0220907

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: B5D85_RS02280
• Genome accession: NZ_CP020082
• Coordinates: 416328..417329 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain STAB120304
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 411328..422329

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
B5D85_RS02255 (B5D85_02255)	-	412002..412685 (-)	684	WP_023078761.1	DUF969 domain-containing protein	-
B5D85_RS02260 (B5D85_02260)	-	412896..413822 (-)	927	WP_076639582.1	glycosyltransferase family 2 protein	-
B5D85_RS02265 (B5D85_02265)	-	413967..414344 (-)	378	WP_076639581.1	VOC family protein	-
B5D85_RS02270 (B5D85_02270)	-	414355..415020 (-)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
B5D85_RS02275 (B5D85_02275)	-	415069..416154 (-)	1086	WP_076639580.1	aminopeptidase P family protein	-
B5D85_RS02280 (B5D85_02280)	ccpA	416328..417329 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
B5D85_RS02285 (B5D85_02285)	-	417460..418458 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
B5D85_RS02290 (B5D85_02290)	-	418460..419794 (+)	1335	WP_076639579.1	glycosyltransferase family 4 protein	-
B5D85_RS02295 (B5D85_02295)	thrS	420216..422159 (+)	1944	WP_076639578.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=220907 B5D85_RS02280 WP_002985680.1 416328..417329(+) (ccpA) [Streptococcus pyogenes strain STAB120304]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=220907 B5D85_RS02280 WP_002985680.1 416328..417329(+) (ccpA) [Streptococcus pyogenes strain STAB120304]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACTAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559