Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrB   Type   Machinery gene
Locus tag   MW_RS00200 Genome accession   NC_003923
Coordinates   46367..47995 (-) Length   542 a.a.
NCBI ID   WP_001186600.1    Uniprot ID   Q4JFB1
Organism   Staphylococcus aureus subsp. aureus MW2     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 39602..54973 46367..47995 within 0


Gene organization within MGE regions


Location: 39602..54973
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MW_RS00165 (MW0031) mecA 39602..41611 (-) 2010 WP_001801873.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -
  MW_RS00170 (MW0032) - 41708..42694 (+) 987 WP_001549960.1 beta-lactam sensor/signal transducer MecR1 -
  MW_RS00175 - 42684..42926 (+) 243 Protein_32 type I restriction enzyme endonuclease domain-containing protein -
  MW_RS00180 (MW0034) - 42917..44527 (-) 1611 Protein_33 IS1182 family transposase -
  MW_RS00185 (MW0035) - 44576..45082 (-) 507 WP_001092189.1 DUF1643 domain-containing protein -
  MW_RS00190 (MW0036) - 45097..45408 (-) 312 WP_000700851.1 DUF960 family protein -
  MW_RS00195 (MW0037) - 45495..45845 (-) 351 WP_000849672.1 SAUGI family uracil-DNA glycosylase inhibitor -
  MW_RS00200 (MW0038) ccrB 46367..47995 (-) 1629 WP_001186600.1 cassette chromosome recombinase CcrB Machinery gene
  MW_RS00205 (MW0039) ccrA 48017..49366 (-) 1350 WP_000815641.1 cassette chromosome recombinase CcrA Machinery gene
  MW_RS00210 (MW0040) cch1 49600..51387 (-) 1788 WP_000122620.1 cassette chromosome replicative helicase -
  MW_RS00215 (MW0041) ssb 51387..51677 (-) 291 WP_001036438.1 cassette chromosome ssDNA-binding protein -
  MW_RS00220 (MW0042) - 51816..52865 (+) 1050 WP_000613248.1 hypothetical protein -
  MW_RS00225 (MW0043) - 53483..54973 (+) 1491 WP_000554504.1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 542 a.a.        Molecular weight: 62769.00 Da        Isoelectric Point: 9.8480

>NTDB_id=22079 MW_RS00200 WP_001186600.1 46367..47995(-) (ccrB) [Staphylococcus aureus subsp. aureus MW2]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKDGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRANVIEDYVMKQILEIVKSDKIIERVVARVNQENQVDCASLHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITYQINQLKNQQNEDKTLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI

Nucleotide


Download         Length: 1629 bp        

>NTDB_id=22079 MW_RS00200 WP_001186600.1 46367..47995(-) (ccrB) [Staphylococcus aureus subsp. aureus MW2]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTTTCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGATGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTGTCAGAGCGTATGGAAGTCAATACTTCTTCTGGTAAACTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGTAAC
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGACATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTGAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCTCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACCAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTAATGTGATTGAAGATTATGTGATGAAGCAAATACTCGAAATAGTCAAAAGTGATAAAATCATTGAACGTGTTG
TAGCACGTGTTAACCAAGAAAATCAAGTTGATTGTGCGTCACTTCATCACGATATCGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGTATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGACTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATTAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTATTTT
TGCCCCAAACACTATATCTTACTATTTAG

Domains

Predicted by InterproScan.

Ogr/Delta-like zinc finger (Ogr_Delta)

(301-356)

Resolvase, N terminal domain (Resolvase)

(11-156)

Recombinase (Recombinase)

(180-280)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4JFB1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrB Staphylococcus aureus N315

98.155

100

0.982

Multiple sequence alignment