Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   BS21228_RS06490 Genome accession   NZ_CP020023
Coordinates   1188091..1188735 (-) Length   214 a.a.
NCBI ID   WP_003220716.1    Uniprot ID   -
Organism   Bacillus subtilis strain ATCC 21228     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 1183091..1193735
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BS21228_RS06455 (BS21228_06410) mrpB 1184283..1184714 (+) 432 WP_003228819.1 Na(+)/H(+) antiporter subunit B -
  BS21228_RS06460 (BS21228_06415) mrpC 1184714..1185055 (+) 342 WP_014480700.1 Na(+)/H(+) antiporter subunit C -
  BS21228_RS06465 (BS21228_06420) mrpD 1185048..1186529 (+) 1482 WP_033881486.1 Na+/H+ antiporter subunit D -
  BS21228_RS06470 (BS21228_06425) mrpE 1186535..1187011 (+) 477 WP_003228815.1 Na+/H+ antiporter subunit E -
  BS21228_RS06475 (BS21228_06430) mrpF 1187011..1187295 (+) 285 WP_003228814.1 Na(+)/H(+) antiporter subunit F1 -
  BS21228_RS06480 (BS21228_06435) mnhG 1187279..1187653 (+) 375 WP_014477830.1 monovalent cation/H(+) antiporter subunit G -
  BS21228_RS06485 (BS21228_06440) yuxO 1187692..1188072 (-) 381 WP_017695528.1 hotdog fold thioesterase -
  BS21228_RS06490 (BS21228_06445) comA 1188091..1188735 (-) 645 WP_003220716.1 two-component system response regulator ComA Regulator
  BS21228_RS06495 (BS21228_06450) comP 1188816..1191128 (-) 2313 WP_014480703.1 sensor histidine kinase Regulator
  BS21228_RS06500 (BS21228_06455) comX 1191144..1191365 (-) 222 WP_014480704.1 competence pheromone ComX -
  BS21228_RS06505 (BS21228_06460) - 1191367..1192230 (-) 864 WP_014480705.1 polyprenyl synthetase family protein -
  BS21228_RS06510 (BS21228_06465) degQ 1192415..1192555 (-) 141 WP_003220708.1 degradation enzyme regulation protein DegQ Regulator
  BS21228_RS22775 - 1192777..1192902 (+) 126 WP_003228793.1 hypothetical protein -
  BS21228_RS06515 (BS21228_06470) - 1193016..1193384 (+) 369 WP_014477834.1 hypothetical protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24128.51 Da        Isoelectric Point: 4.6857

>NTDB_id=220324 BS21228_RS06490 WP_003220716.1 1188091..1188735(-) (comA) [Bacillus subtilis strain ATCC 21228]
MKKILVIDDHPAVMEGTKTILETDSNLSVDCLSPEPSEQFIKQHDFSSYDLILMDLNLGGEVNGMELSKQILQENPHCKI
IVYTGYEVEDYFEEAIRAGLHGAISKTESKEKITQYIYHVLNGEILVDFAYFKQLMTQQKTKPAPSSQKEQDVLTPRECL
ILQEVEKGFTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDGVL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=220324 BS21228_RS06490 WP_003220716.1 1188091..1188735(-) (comA) [Bacillus subtilis strain ATCC 21228]
ATGAAAAAGATACTAGTGATTGATGACCATCCGGCTGTCATGGAAGGCACCAAGACAATTTTGGAAACGGATTCGAATTT
GTCTGTTGATTGTCTCAGTCCTGAACCGAGCGAACAGTTTATCAAGCAGCATGATTTCTCGTCATATGATCTCATTTTAA
TGGATCTGAATCTAGGCGGCGAGGTCAATGGGATGGAGCTTTCTAAACAGATTTTACAAGAGAATCCTCATTGTAAAATT
ATCGTGTATACCGGTTATGAGGTCGAGGATTATTTCGAGGAAGCGATTCGTGCGGGTCTGCACGGTGCCATCAGCAAAAC
GGAATCTAAAGAAAAGATCACCCAATACATATACCACGTACTCAATGGAGAAATTTTAGTCGATTTTGCTTACTTTAAAC
AGCTGATGACTCAGCAAAAAACAAAGCCGGCTCCTTCCTCTCAAAAAGAACAAGATGTGCTCACACCTAGAGAATGCCTG
ATTCTTCAAGAAGTTGAAAAAGGATTTACAAACCAAGAAATCGCAGATGCCCTTCATTTAAGCAAGCGGTCCATTGAATA
CAGCTTGACATCGATTTTCAATAAGCTGAATGTCGGTTCACGGACGGAAGCGGTTTTGATAGCGAAATCAGACGGTGTAC
TTTAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(152-208)

Response regulator receiver domain (Response_reg)

(4-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

100

100

1

Multiple sequence alignment