Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   B4602_RS02645 Genome accession   NZ_CP020020
Coordinates   541878..542447 (+) Length   189 a.a.
NCBI ID   WP_000872874.1    Uniprot ID   -
Organism   Staphylococcus aureus strain ATCC 6538     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 536878..547447
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  B4602_RS02620 cysE 538091..538738 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  B4602_RS02625 cysS 538722..540122 (+) 1401 WP_000631974.1 cysteine--tRNA ligase -
  B4602_RS02630 - 540115..540519 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  B4602_RS02635 rlmB 540527..541273 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  B4602_RS02640 - 541273..541797 (+) 525 WP_000664738.1 NYN domain-containing protein -
  B4602_RS02645 sigH 541878..542447 (+) 570 WP_000872874.1 RNA polymerase sigma factor Regulator
  B4602_RS02650 rpmG 542562..542705 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  B4602_RS02655 secE 542761..542943 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  B4602_RS02660 nusG 542956..543504 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  B4602_RS02665 rplK 543685..544107 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  B4602_RS02670 rplA 544315..545007 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  B4602_RS02675 rplJ 545279..545779 (+) 501 WP_042727573.1 50S ribosomal protein L10 -
  B4602_RS02680 rplL 545822..546190 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  B4602_RS02685 - 546365..546973 (+) 609 WP_000020304.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23043.97 Da        Isoelectric Point: 9.6030

>NTDB_id=220222 B4602_RS02645 WP_000872874.1 541878..542447(+) (sigH) [Staphylococcus aureus strain ATCC 6538]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCKQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=220222 B4602_RS02645 WP_000872874.1 541878..542447(+) (sigH) [Staphylococcus aureus strain ATCC 6538]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTAAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

98.413

100

0.984
  sigH Staphylococcus aureus MW2

98.413

100

0.984

Multiple sequence alignment